TEST BANK
Essentials of Genetics 8th Editionby William S. Klug
St
oi
cn
ur
se
TEST BANK
,William: Essentials of Genetics
Multiple Choice
1) A protein is 300 amino acids long. Which of the following could be the number of nucleotides in
the section of DNA that codes for this protein? (Remember: DNA is double-stranded.)
E) 1800
2) A short segment of an mRNA molecule is shown below. The polypeptide it codes for is also
St
shown:
5′-AUGGUGCUGAAG : methionine-valine-leucine-lysine
oi
Assume that a mutation in the DNA occurs so that the fourth base (counting from the 5′ end) of the
messenger RNA now reads A rather than G. What sequence of amino acids will the mRNA now code
for? (You do not need a copy of the genetic code to answer the question.)
cn
E) methionine-methionine-leucine-lysine
ur
3) The term peptidyl transferase relates to .
B) peptide bond formation during protein synthesis
se
4) Which of the following are among the major components of prokaryotic ribosomes?
C) 16S rRNA, 5S rRNA, and 23S rRNA
5) The one-gene:one-enzyme hypothesis emerged from work on which two organisms?
1. A) coli and yeast
2. B) Drosophila and humans
3. C) Neurospora and Drosophila
4. D) coli and humans
5. E) All of the answers listed are correct.
6) By their experimentation using the Neurospora fungus, Beadle and Tatum were able to propose
,the far-reaching hypothesis that .
C) the role of a specific gene is to produce a specific enzyme
St
oi
cn
ur
se
, 7) The β chain of adult hemoglobin is composed of 146 amino acids of a known sequence. In
comparing the normal β chain with the β chain in sickle cell hemoglobin, what alteration is one likely
to find?
B) glutamic acid replacing valine in the first position
8) The primary structure of a protein is determined by .
A) the sequence of amino acids
9) Which protein class directly controls many of the metabolic reactions within a cell?
D) enzymes
St
10) The secondary structure of a protein includes .
C) α-helix and β-pleated sheet
oi
11) Side groups of amino acids are typically classified under which of the following?
cn
A) polar, nonpolar
12) Nutritional mutations can be defined as .
A) those mutations that do not allow a bacterium or fungus to grow on minimal medium but
ur
do allow growth on complete medium
se
2) Conditional mutations are more likely to result from a mutation caused by which of the following
alterations to the coding region of a gene?
E) tautomeric shift
3) A class of mutations that results in multiple contiguous amino acid changes in proteins is likely to
be which of the following?
D) frameshift
4) Two formal terms used to describe categories of mutational nucleotide substitutions in DNA are
.
Essentials of Genetics 8th Editionby William S. Klug
St
oi
cn
ur
se
TEST BANK
,William: Essentials of Genetics
Multiple Choice
1) A protein is 300 amino acids long. Which of the following could be the number of nucleotides in
the section of DNA that codes for this protein? (Remember: DNA is double-stranded.)
E) 1800
2) A short segment of an mRNA molecule is shown below. The polypeptide it codes for is also
St
shown:
5′-AUGGUGCUGAAG : methionine-valine-leucine-lysine
oi
Assume that a mutation in the DNA occurs so that the fourth base (counting from the 5′ end) of the
messenger RNA now reads A rather than G. What sequence of amino acids will the mRNA now code
for? (You do not need a copy of the genetic code to answer the question.)
cn
E) methionine-methionine-leucine-lysine
ur
3) The term peptidyl transferase relates to .
B) peptide bond formation during protein synthesis
se
4) Which of the following are among the major components of prokaryotic ribosomes?
C) 16S rRNA, 5S rRNA, and 23S rRNA
5) The one-gene:one-enzyme hypothesis emerged from work on which two organisms?
1. A) coli and yeast
2. B) Drosophila and humans
3. C) Neurospora and Drosophila
4. D) coli and humans
5. E) All of the answers listed are correct.
6) By their experimentation using the Neurospora fungus, Beadle and Tatum were able to propose
,the far-reaching hypothesis that .
C) the role of a specific gene is to produce a specific enzyme
St
oi
cn
ur
se
, 7) The β chain of adult hemoglobin is composed of 146 amino acids of a known sequence. In
comparing the normal β chain with the β chain in sickle cell hemoglobin, what alteration is one likely
to find?
B) glutamic acid replacing valine in the first position
8) The primary structure of a protein is determined by .
A) the sequence of amino acids
9) Which protein class directly controls many of the metabolic reactions within a cell?
D) enzymes
St
10) The secondary structure of a protein includes .
C) α-helix and β-pleated sheet
oi
11) Side groups of amino acids are typically classified under which of the following?
cn
A) polar, nonpolar
12) Nutritional mutations can be defined as .
A) those mutations that do not allow a bacterium or fungus to grow on minimal medium but
ur
do allow growth on complete medium
se
2) Conditional mutations are more likely to result from a mutation caused by which of the following
alterations to the coding region of a gene?
E) tautomeric shift
3) A class of mutations that results in multiple contiguous amino acid changes in proteins is likely to
be which of the following?
D) frameshift
4) Two formal terms used to describe categories of mutational nucleotide substitutions in DNA are
.
