MOLECULAR BIOLOGY EXAM: LATEST A+ QUESTIONS
AND ANSWERS BREAKDOWN
Nucleotide
Monomer of DNA
Nucleoside
Molecule of ribose plus base
2-deoxyribose
sugar that has a H at the 2' C
Ribose
Name of five carbon sugar that is found in RNA
Basepair
Two nucleotides, one with a purine & one with a pyrimidine, connected by H bonds
Antiparallel means
the two polynucleotide chains/strands run in opposite directions
What two factors are the main determination of the Tm of DNA
Amount of G:C's & overall strand length
How many rings do purines & pyrimidines have?
Purines: 2
Pyrimidines:1
The DNA from two different species can often be distinguished by a difference in the____.
Ratio of A+T to G+C
What is the difference between Uracil & Thymine
Thymine has a methyl group
What did the X-ray diffraction patterns produced by Rosalind Franklin initially reveal about
the DNA molecule?
It is a helical structure with distinct regularities
You have 340 nm of double stranded B form DNA. How many 360 degree turns are present in
the double helix?
, 100
You have 340 nm of double stranded B form DNA. How many nucleotides are present? Be
careful!
2000
DNA and RNA both contain phosphate and deoxyribose. (True or False)
False
In general, the keto form of thymine is more abundant than the enol form. (True or False)
True
Left-Handed helical form of DNA
Z-DNA
DNA that results from reduced humidity around the DNA and is more tightly wound
A-DNA
DNA that most closely resembles the Watson & Crick model
B-DNA
Term used to describe the amount of the double helix crossing over itself
Writhe
Number of helical turns in a given space
Twist
What are the main RNA secondary structures?
Bulge-loop, hairpin, pseudoknot, internal loop, and double helix
A closer association between DNA and histones most likely causes___.
repression in gene expression
Which amino acids of histone N-termini can be acetylated and deacetylated?
Lysines
RNA can form Beta Sheets (True or False)
False
What technique is most commonly used to study the secondary structure of RNA?
AND ANSWERS BREAKDOWN
Nucleotide
Monomer of DNA
Nucleoside
Molecule of ribose plus base
2-deoxyribose
sugar that has a H at the 2' C
Ribose
Name of five carbon sugar that is found in RNA
Basepair
Two nucleotides, one with a purine & one with a pyrimidine, connected by H bonds
Antiparallel means
the two polynucleotide chains/strands run in opposite directions
What two factors are the main determination of the Tm of DNA
Amount of G:C's & overall strand length
How many rings do purines & pyrimidines have?
Purines: 2
Pyrimidines:1
The DNA from two different species can often be distinguished by a difference in the____.
Ratio of A+T to G+C
What is the difference between Uracil & Thymine
Thymine has a methyl group
What did the X-ray diffraction patterns produced by Rosalind Franklin initially reveal about
the DNA molecule?
It is a helical structure with distinct regularities
You have 340 nm of double stranded B form DNA. How many 360 degree turns are present in
the double helix?
, 100
You have 340 nm of double stranded B form DNA. How many nucleotides are present? Be
careful!
2000
DNA and RNA both contain phosphate and deoxyribose. (True or False)
False
In general, the keto form of thymine is more abundant than the enol form. (True or False)
True
Left-Handed helical form of DNA
Z-DNA
DNA that results from reduced humidity around the DNA and is more tightly wound
A-DNA
DNA that most closely resembles the Watson & Crick model
B-DNA
Term used to describe the amount of the double helix crossing over itself
Writhe
Number of helical turns in a given space
Twist
What are the main RNA secondary structures?
Bulge-loop, hairpin, pseudoknot, internal loop, and double helix
A closer association between DNA and histones most likely causes___.
repression in gene expression
Which amino acids of histone N-termini can be acetylated and deacetylated?
Lysines
RNA can form Beta Sheets (True or False)
False
What technique is most commonly used to study the secondary structure of RNA?
