MED 118: CHAPTER 9. AN ULTIMATE A+ QUESTIONS AND
ANSWERS BREAKDOWN
Which of the following medications is a selective COX-2 inhibitor?
A. Acetaminophen (Tylenol)
B. Ibuprofen (Advil, Motrin)
C. Celecoxib (Celebrex)
D. Meloxicam (Mobic)
C. celecoxib (Celebrex)
To which DEA schedule do fentanyl, oxycodone, and morphine belong?
C-II
To which opioid side effect would a patient likely not develop tolerance over
time?
Miosis or constipation
Opioid Antagonist drug
naloxone (Narcan)
Which medicine(s) may help with an acute attack of migraines?
NSAIDs or serotonin receptor agonists (triptans)
Which OTC supplement combination would benefit an osteoporosis patient the
most?
Calcium and Vitamin D
NSAIDs
nonsteroidal anti-inflammatory drugs
Enzyme that most NSAIDs inhibit?
COX (cyclooxygenase)
"Bad COX", causes many of the effects involved with inflammatory and pain
process, inhibition of this leads to suppression of inflammation, a reduction in
pain and fever, colorectal protection
COX-2
"Good COX", involved in the stomach lining, kidneys, and a response to bleeding.
Helps control gastric erosion and ulcers, kidney impairment and bleeding. When
inhibited, causes these problems
, COX-1
COX inhibitors that inhibit both COX-1 and COX-2 (ex:ibuprofen, naproxen and
meloxicam)
Nonselective COX inhibitor
COX inhibitor that inhibits only COX-2
celecoxib (Celebrex)
First of the NSAID class, old medicine, irreversible, non-selective COX inhibitor
(effects on platelets last for days)
aspirin (ASA)
Reye syndrome
encephalopathy and liver damage in children following an acute viral illness; linked to
aspirin use
2nd generation NSAID
Which generation of nonaspirin NSAIDs will show a preference for COX-2 inhibition?
Cardiovascular risks
Why is celecoxib (Celebrex) the last choice drug for long term pain management?
Inflammation
acetaminophen (Tylenol) is used for mild to moderate pain and fever. To which does it
have no effect on?
mu, kappa, and delta
opioid receptors (3)
delta receptor
Which opioid receptor do opioids not interact with?
morphine (Kadian, MS Contin)
opioid analgesic; schedule II; Kadian is extended-release morphine; MS Contin is
continuous release. Strong agonist for mu and kappa receptors. All other opioids are
measured against this opioid
Miosis
constricted pupils. In toxic doses of opioids, the pupils may constrict to pinpoint size
Tolerance
ANSWERS BREAKDOWN
Which of the following medications is a selective COX-2 inhibitor?
A. Acetaminophen (Tylenol)
B. Ibuprofen (Advil, Motrin)
C. Celecoxib (Celebrex)
D. Meloxicam (Mobic)
C. celecoxib (Celebrex)
To which DEA schedule do fentanyl, oxycodone, and morphine belong?
C-II
To which opioid side effect would a patient likely not develop tolerance over
time?
Miosis or constipation
Opioid Antagonist drug
naloxone (Narcan)
Which medicine(s) may help with an acute attack of migraines?
NSAIDs or serotonin receptor agonists (triptans)
Which OTC supplement combination would benefit an osteoporosis patient the
most?
Calcium and Vitamin D
NSAIDs
nonsteroidal anti-inflammatory drugs
Enzyme that most NSAIDs inhibit?
COX (cyclooxygenase)
"Bad COX", causes many of the effects involved with inflammatory and pain
process, inhibition of this leads to suppression of inflammation, a reduction in
pain and fever, colorectal protection
COX-2
"Good COX", involved in the stomach lining, kidneys, and a response to bleeding.
Helps control gastric erosion and ulcers, kidney impairment and bleeding. When
inhibited, causes these problems
, COX-1
COX inhibitors that inhibit both COX-1 and COX-2 (ex:ibuprofen, naproxen and
meloxicam)
Nonselective COX inhibitor
COX inhibitor that inhibits only COX-2
celecoxib (Celebrex)
First of the NSAID class, old medicine, irreversible, non-selective COX inhibitor
(effects on platelets last for days)
aspirin (ASA)
Reye syndrome
encephalopathy and liver damage in children following an acute viral illness; linked to
aspirin use
2nd generation NSAID
Which generation of nonaspirin NSAIDs will show a preference for COX-2 inhibition?
Cardiovascular risks
Why is celecoxib (Celebrex) the last choice drug for long term pain management?
Inflammation
acetaminophen (Tylenol) is used for mild to moderate pain and fever. To which does it
have no effect on?
mu, kappa, and delta
opioid receptors (3)
delta receptor
Which opioid receptor do opioids not interact with?
morphine (Kadian, MS Contin)
opioid analgesic; schedule II; Kadian is extended-release morphine; MS Contin is
continuous release. Strong agonist for mu and kappa receptors. All other opioids are
measured against this opioid
Miosis
constricted pupils. In toxic doses of opioids, the pupils may constrict to pinpoint size
Tolerance
