COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE
Basic premise of signal transduction
Trying to get a message from outside the cell to generate a response inside the cell
What does CDK stand for
cyclin dependent kinase
what is the basic premise of cyclins
To cycle proteins during the cell cycle.
what is the basic premise of CDKs
Proteins that depend on cyclins
Universal requirement of somatic cells
must divide, producing one copy of their entire genome (with no mutations), as well as 2
daughter cells (critical point)
what are the key points of the cell cycle
1. Interphase
2. M phase
Features of interphase
- Longest phase in cycle
- 90% of a cell's life
- Chromosomes elongated - chromatin
- Cells very active
, - includes G1 ( 1st growth phase) , S (time when DNA is synthesised to produce
another copy) and G2 phase (2nd growth phase)
What must happen during G1 phase
cells must express all proteins necessary for metabolism, and duplicate all organelles in
cells
What happens during S phase
cells must replicate DNA and all of the chromosomes present within the cell must be
replicated.
What happens during G2 phase
another period of cell growth, were the cell needs to prepare for mitosis (duplication and
separation of chromosomes)
Features of M phase
-Mitosis (segregation of duplicate chromosomes)
-cytokines (division of entire cell into 2 daughter cells. with chromosomes being passed
to 2 daughter cells)
- relatively short (1 hour)
Purpose of the Cell cycle
use checkpoints to act as integrity checkers to stop the passing on of mutations to
daughter cells= stoping the passing of catastrophic effects on the cell.
Two Main checkpoints
G1--> S transition point (restriction point or start)
G2--> M transition
G1--> S transition point