Exam 4: AMLS, Lymphoid Neoplasms, & Cytochemical Stains Questions and Answers 2025/2026( A+ GRADED 100% VERIFIED).

Exam 4: AMLS, Lymphoid Neoplasms, &
Cytochemical Stains
All of the following are general characteristics of acute myeloid leukemias except:
a.
Thrombocytosis
b.
Normocytic, normochromic anemia
c.
Neoplastic proliferation and accumulation of immature and non-functional cells in the
bone marrow
d.
Myelodysplasia of neutrophils
Thrombocytosis


Which of the following CD markers would you expect to see on the lymphocytes from a
patient with Chronic Lymphocytic Leukemia (CLL)?
a.
CD2
b.
CD19
c.
CD13
d.
CD34
CD19


Auer rods are composed of:
a.
Fused primary granules
b.
Fused secondary granules
c.
Fused DNA remnants
d.
Fused RNA remnants
Fused primary granules

,The diagnostic chromosomal abnormality t(8:21)(q22;q22.3) resulting in the RUNX1 gene
rearrangement is associated with which of the following FAB classes of leukemia?
a.
AML M1
b.
AML M2
c.
AML M3
d.
ALL L3
AML M2


The diagnostic chromosomal abnormality t(8:14)(q24;q32) resulting in the cMYC gene
rearrangement is associated with which of the following FAB classes of leukemia?
a.
AML M1
b.
AML M2
c.
AML M3
d.
ALL L3
ALL L3


The diagnostic chromosomal abnormality t(15:17)(q22;q12) resulting in the PML/RARα
gene is associated with which of the following FAB classes of leukemia?
a.
AML M1
b.
AML M2
c.
AML M3
d.
ALL L3
AML M3


Which AML FAB subgroup is treated with Retinoic Acid?
a.
AML M1

, b.
AML M2
c.
AML M3
d.
AML M5
AML M3


What enzymatic cytochemical stain reacts with the primary granules of neutrophils,
basophils and eosinophils?
a.
Myeloperoxidase (MPO)
b.
Sudan Black B (SBB)
c.
Leukocyte Alkaline Phosphatase (LAP)
d.
Periodic Acid-Schiff (PAS)
Myeloperoxidase (MPO)


Which of the following cytochemical pairings is incorrect?

a.

AML M0: MPO(+), SE(+)

b.

AML M2: MPO(+), SBB(+)

c.

AML M4: SE(+), NSE(+)

d.

AML M6: MPO(=), PAS(+)

e.

All of the above cytochemical pairings are correct