Pharmacotherapeutics for Advanced Practice
Nurse Prescribers 6th (All Chapters, 100%
Original Verified, A+ Grade) Brand New!!!
_____________________________________________________________________________________
What is a schedule V drug?
Same as all prescription drugs, and may be dispensed without a prescription unless state
regulated. Texas law requires a prescription for Schedule V drugs.
What are examples of schedule V drugs?
Loperamide, diphenoxylate, pregabalin, cough medications with less than 200mg/100ml
T/F, some state practice acts may be more stringent than federal laws.
True, THE STRICTER ACT OR LAW IS DOMINANT.
A practitioner prescribes codeine for a patient who is postoperative following knee surgery. What
schedule drug is being prescribed?
A. Schedule 1
B. Schedule 2
C. Schedule 3
D. Schedule 4
E. Schedule 5
C. Schedule 3
Rationale: Examples of Schedule 3 drugs are certain narcotics such as codeine and
nonbarbiturate sedatives.
What is part A of the Texas BON rule 222.8 Authority to Order and Prescribe Controlled Substances?
Comply with all federal and state laws and regulations including United States Drug Enforcement
Administration.
NEED DEA #
What is part B of the Texas BON rule 222.8 Authority to Order and Prescribe Controlled Substances?
Orders and prescriptions for controlled substances in Schedules III through V may be authorized,
provided certain requirements are met.
What is part C of the Texas BON rule 222.8 Authority to Order and Prescribe Controlled Substances?
Orders and prescriptions for controlled substances in Schedule II may be authorized only in
hospital setting, admitted to hospital, in ED, or terminal illness (hospice).
,What is the Prescription Monitoring Program of Texas?
Collects and monitors prescription data for all Schedule II, III, IV, and V Controlled Substances
(CS) dispensed by a pharmacy in Texas or to a Texas resident from a pharmacy located in
another state.
When do pharmacies need to report dispensed controlled substance records according to the PMP?
No later than next business day.
What does the PMP require as of 3/1/2020?
Pharmacists and prescribers (other than a veterinarian) will be required to check the patient's
PMP history before dispensing or prescribing opioids, benzodiazepines, barbiturates, or
carisoprodol.
What is the National Provider Identifier (NPI)?
Consists of 10 digits, and each health care provider and practitioner who bills for services must
obtain one.
What are Pharmacodynamics?
Relationship between the drug concentration and the patient's response to the drug... it is what
the drug does to the body.
What is the variation in drug response explained by?
By variations in environmental and genetic factors.
How do most drugs work?
By binding to receptors.
What is the receptor theory?
Drugs act by binding to receptors.
What happens once drugs are bound to receptors?
Initiates biochemical & physiological changes characteristic of the response to the drug,
hormone, or neurotransmitter.
What does the receptor theory require?
Affinity and efficacy.
What is affinity?
Attraction between a drug and its receptor.
What is efficacy?
Ability of a drug to activate a receptor and produce an effect.
, What is the lock and key mechanism of receptors in receptor theory?
The drug molecule must "fit" into the receptor like a lock and key mechanism (not always this
simplistic).
What is the dose-response curve?
Intensity of response produced by a drug is related to the number of receptors occupied thus is
proportional to the dose/ concentration of the drug.
What occurs at 50% max response during the dose-response curve?
50% of the max response occurs at a dose/ concentration at which a drug occupies 50% of its
receptors.
What happens if a dose is below the curve in dose-response?
Do not produce pharmacological response.
What happens if a dose is above the curve in dose-response?
Do not produce additional pharmacological response, may have toxicity.
What is efficacy in regards to dose-response?
Maximum effect that a drug can produce regardless of dose (e.g., drugs used to treat mild pain
will not work on severe pain no matter the dose.)
What is potency in regards to dose-response?
The difference in concentration or dosage of different drugs required to produce similar effect.
Based on the graph, which medication is most potent and which is least?
Red is most potent, green is least.
What is ED50?
Dose required to produce a specific effect in 50% of patients.
What is LD50?
Lethal dose for 50% of the population.
Is drug-receptor binding reversible?
Yes, almost always.
What are the two types of drug responses (curves)?
Graded and quantal.
What are graded responses?
Nurse Prescribers 6th (All Chapters, 100%
Original Verified, A+ Grade) Brand New!!!
_____________________________________________________________________________________
What is a schedule V drug?
Same as all prescription drugs, and may be dispensed without a prescription unless state
regulated. Texas law requires a prescription for Schedule V drugs.
What are examples of schedule V drugs?
Loperamide, diphenoxylate, pregabalin, cough medications with less than 200mg/100ml
T/F, some state practice acts may be more stringent than federal laws.
True, THE STRICTER ACT OR LAW IS DOMINANT.
A practitioner prescribes codeine for a patient who is postoperative following knee surgery. What
schedule drug is being prescribed?
A. Schedule 1
B. Schedule 2
C. Schedule 3
D. Schedule 4
E. Schedule 5
C. Schedule 3
Rationale: Examples of Schedule 3 drugs are certain narcotics such as codeine and
nonbarbiturate sedatives.
What is part A of the Texas BON rule 222.8 Authority to Order and Prescribe Controlled Substances?
Comply with all federal and state laws and regulations including United States Drug Enforcement
Administration.
NEED DEA #
What is part B of the Texas BON rule 222.8 Authority to Order and Prescribe Controlled Substances?
Orders and prescriptions for controlled substances in Schedules III through V may be authorized,
provided certain requirements are met.
What is part C of the Texas BON rule 222.8 Authority to Order and Prescribe Controlled Substances?
Orders and prescriptions for controlled substances in Schedule II may be authorized only in
hospital setting, admitted to hospital, in ED, or terminal illness (hospice).
,What is the Prescription Monitoring Program of Texas?
Collects and monitors prescription data for all Schedule II, III, IV, and V Controlled Substances
(CS) dispensed by a pharmacy in Texas or to a Texas resident from a pharmacy located in
another state.
When do pharmacies need to report dispensed controlled substance records according to the PMP?
No later than next business day.
What does the PMP require as of 3/1/2020?
Pharmacists and prescribers (other than a veterinarian) will be required to check the patient's
PMP history before dispensing or prescribing opioids, benzodiazepines, barbiturates, or
carisoprodol.
What is the National Provider Identifier (NPI)?
Consists of 10 digits, and each health care provider and practitioner who bills for services must
obtain one.
What are Pharmacodynamics?
Relationship between the drug concentration and the patient's response to the drug... it is what
the drug does to the body.
What is the variation in drug response explained by?
By variations in environmental and genetic factors.
How do most drugs work?
By binding to receptors.
What is the receptor theory?
Drugs act by binding to receptors.
What happens once drugs are bound to receptors?
Initiates biochemical & physiological changes characteristic of the response to the drug,
hormone, or neurotransmitter.
What does the receptor theory require?
Affinity and efficacy.
What is affinity?
Attraction between a drug and its receptor.
What is efficacy?
Ability of a drug to activate a receptor and produce an effect.
, What is the lock and key mechanism of receptors in receptor theory?
The drug molecule must "fit" into the receptor like a lock and key mechanism (not always this
simplistic).
What is the dose-response curve?
Intensity of response produced by a drug is related to the number of receptors occupied thus is
proportional to the dose/ concentration of the drug.
What occurs at 50% max response during the dose-response curve?
50% of the max response occurs at a dose/ concentration at which a drug occupies 50% of its
receptors.
What happens if a dose is below the curve in dose-response?
Do not produce pharmacological response.
What happens if a dose is above the curve in dose-response?
Do not produce additional pharmacological response, may have toxicity.
What is efficacy in regards to dose-response?
Maximum effect that a drug can produce regardless of dose (e.g., drugs used to treat mild pain
will not work on severe pain no matter the dose.)
What is potency in regards to dose-response?
The difference in concentration or dosage of different drugs required to produce similar effect.
Based on the graph, which medication is most potent and which is least?
Red is most potent, green is least.
What is ED50?
Dose required to produce a specific effect in 50% of patients.
What is LD50?
Lethal dose for 50% of the population.
Is drug-receptor binding reversible?
Yes, almost always.
What are the two types of drug responses (curves)?
Graded and quantal.
What are graded responses?
