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Viruses
Require host to replicate
Viroids
Small RNA molecules that catalyze replication steps
RNA viruses
Depend on RNA polymerases from host or helper viruses
DNA-based world
Transition from self-replicating RNA molecules to DNA production
Reverse transcriptase
Enzyme that makes DNA copies of RNA
DNA stability
Advantage of DNA over RNA
RNA-dependent RNA polymerases
Enzymes for RNA replication
RNA-dependent DNA polymerases
Enzymes for reverse transcription (RNA to DNA)
DNA-dependent RNA polymerases
Enzymes for transcription (DNA to mRNA)
DNA-dependent DNA polymerases
, Enzymes for DNA replication
Small and medium-sized DNA viruses
Arise as independently replicating genetic elements in cells
Large DNA viruses
Evolve from cellular forms that became intracellular parasites
Viral genes
Encode for structural proteins, DNA replication enzymes, and assembly machinery
Seven Major Virus Groups
Classifications based on genome type and characteristics
Group 1
Viruses with small ssDNA genomes, without envelopes
Group 2
Viruses with widespread dsDNA genomes, can be very large
Group 3
Viruses with + strand RNA genomes, common in plants and vertebrates
Group 4
Viruses with - strand RNA genomes, major infectious diseases in humans
Group 5
Viruses with dsRNA genomes, mostly in fungi
Group 6
Viruses that use reverse transcriptase (DNA or RNA)
Group 7
Satellite viruses, nucleic acids, and viroids with small genomes