BIOC20 LECTURE 8 EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS LATEST UPDATE
Filoviridae
Family of filamentous, enveloped RNA viruses.
Negative sense ssRNA
Single-stranded RNA with reverse transcription.
Marburg virus
First identified in 1967, causes severe disease.
Ebolavirus
Emerging virus causing hemorrhagic fever.
Zaire ebolavirus (ZEBOV)
Most fatal ebolavirus species known.
Sudan ebolavirus (SEBOV)
Ebolavirus species with no vaccine available.
Cote d'Ivoire ebolavirus (CIEBOV)
Third ebolavirus species identified in 1994.
Reston ebolavirus (REBOV)
Non-pathogenic ebolavirus variant in humans.
Bundibugyo Ebola virus (BEBOV)
Ebolavirus discovered in Uganda in 2007.
Hemorrhagic fever
, Severe illness with high mortality rate.
Transmission
Spread through close contact with bodily fluids.
RNA polymerase
Enzyme responsible for RNA synthesis.
Genome size
Filovirus genome length is ~15-19 kb.
Viral proteins
Proteins include GP, NP, VP35, VP40, and more.
RNA editing
Process creating multiple proteins from one gene.
sGP
Secreted glycoprotein produced by RNA editing.
Inclusion bodies
Aggregates of viral proteins/nucleic acids in cells.
Epidemic
Rapid spread of disease in a population.
Vaccination
Preventative measure, ZEBOV vaccine available.
Zoonotic spread
Transmission from animals to humans.
Filamentous structure
Characteristic shape of filovirus particles.
WITH COMPLETE SOLUTIONS LATEST UPDATE
Filoviridae
Family of filamentous, enveloped RNA viruses.
Negative sense ssRNA
Single-stranded RNA with reverse transcription.
Marburg virus
First identified in 1967, causes severe disease.
Ebolavirus
Emerging virus causing hemorrhagic fever.
Zaire ebolavirus (ZEBOV)
Most fatal ebolavirus species known.
Sudan ebolavirus (SEBOV)
Ebolavirus species with no vaccine available.
Cote d'Ivoire ebolavirus (CIEBOV)
Third ebolavirus species identified in 1994.
Reston ebolavirus (REBOV)
Non-pathogenic ebolavirus variant in humans.
Bundibugyo Ebola virus (BEBOV)
Ebolavirus discovered in Uganda in 2007.
Hemorrhagic fever
, Severe illness with high mortality rate.
Transmission
Spread through close contact with bodily fluids.
RNA polymerase
Enzyme responsible for RNA synthesis.
Genome size
Filovirus genome length is ~15-19 kb.
Viral proteins
Proteins include GP, NP, VP35, VP40, and more.
RNA editing
Process creating multiple proteins from one gene.
sGP
Secreted glycoprotein produced by RNA editing.
Inclusion bodies
Aggregates of viral proteins/nucleic acids in cells.
Epidemic
Rapid spread of disease in a population.
Vaccination
Preventative measure, ZEBOV vaccine available.
Zoonotic spread
Transmission from animals to humans.
Filamentous structure
Characteristic shape of filovirus particles.
