STUDYING FOR PCEUT EXAM EVALUATION QUESTIONS
WITH ANSWERS 2025/2026 GRADED A+
The colligative properties of a solution are related to the total number of solute particles
in the solution. - True
Bacteriostatic water for injection, USP, cannot be used for direct injection in neonates. -
True
The solubility of a solute is classified as a colligative property. - False
Elixirs usually contain 50 - 90% alcohol. - False
EDTA could be used as an antioxidant because it is easily oxidized. - False
Ophthalmic solutions are usually buffered to maintain pH, improve stability and/or
solubility of the drug substance, and/or maximize the effectiveness of the preservative. -
True
A surfactant must be an amphiphile with both a hydrophilic group and a hydrophobic
part. - True
The higher the HLB value of a surfactant, the more hydrophobic the surfactant is. -
False
Boric acid cannot be used in ophthalmic solutions as it can penetrate into the eye,
leading to a hypotonic situation for the eye. - False
Capsules of size 2 are larger than those of size 1. - False
Armour thyroid 1 grain is equivalent to 120 mg. - False
Readings are made at the top of the meniscus when one measures aqueous or
alcoholic liquids. - False
The rate of dissolution of a drug from a tablet can be increased by increasing the drug's
particle size. - False
An example of colloid IV solution is normal saline 0.9%. - True
Lipid membrane permeability of a molecule is related to its hydrophobicity. - True
The route of drug administration is dependent on the physical form of drug formulation. -
True
,The concentration unit % (w/v) is defined as milligrams of solute in 100 ml of solution. -
False
Among non-covalent interactions, hydrogen bonds are the strongest interactions. -
False
Cyclosporine readily dissolves in polyoxyethylated castor oil because of strong
electrostatic interactions. - False
According to the Bronsted-Lowry theory, an acid is defined as a substance which is
capable of accepting a proton. - False
The anti-diabetic drug glyburide is a weak acid with a pKa value of approximately 5.
Therefore, glyburide will be nearly 100% ionized in the blood at normal physiological
pH. - True
Buffers are always mixtures of weak acids and their conjugate bases or weak bases
and their conjugate acids. - True
Buffer capacity is determined by both the total buffer concentration and the
concentration ratio of conjugate base to weak acid or weak base to conjugate acid. -
True
The osmolarity of 1/2 Normal Saline is approximately 308 mOsm/L. - False
A patient has severe diarrhea, and his skin and mucous membranes are dry. The
patient could be given oral hypertonic solutions so that the body can become more
hydrated. - False
By definition, the V-value is the volume of sterile water to be added to dissolve 0.3 g of
a drug and make the solution isotonic. - True
Sterile membrane filtration of ophthalmic solutions under aseptic conditions is the
preferred method of sterilization. - True
Parabens could be used as antimicrobial preservatives in ophthalmic solutions. - True
The main mechanism of sodium bisulfite to be used as an antioxidant is that it can
directly reduce already oxidized drugs. - False
A solution that passes a pyrogen test will also pass a test for sterility. - False
One of the main purposes of adding one or more surfactants in dispersed systems is to
reduce interfacial tension and stabilize the system. - True
The higher the HLB value of a surfactant, the more hydrophobic the surfactant. - False
, Tween 80 is derived from Span 80 by adding polar polyoxyethylene groups to non-
esterified hydroxyls, and therefore Tween 80 is more hydrophilic than Span 80. - True
Approximately 15 mg of phenobarbital is to be dispensed when filling a prescription for
Phenobarbital 1/4 grain. - True
Porcelain pestle and glass mortar are the proper tools for reducing a coarse powder into
fine particle-sized powder because glass mortar provides a smooth surface for the
porcelain pestle. - False
Capsules of size 1 are smaller than those of size 3. - False
Sterile water for injection is considered as a hypotonic solution. When given IV, it will
cause cell lysis. - True
In lab, a USP standard sieve is used to obtain the desired particle size of the powder.
The larger the number of the sieve, the larger the particle size. - False
The number of dissolved solute particles in a solution is one of the factors that
determines colligative properties of the solution. - False
For an aqueous pharmaceutical solution at a very low drug concentration, its molarity is
close to its molality. - True
Cyclosporine readily dissolves in castor oil due to van der Waals interactions. - True
If heat of a solution in the process of solubilization of a particle drug (ΔH) is negative, an
increase in temperature will result in an increase in solubility of the drug. - False
Direction of osmosis is the same as the direction of osmotic pressure. - False
Salting out effect has a greater effect on aqueous solubility of electrolytes than non-
electrolytes. - False
The increased aqueous solubility of prenisolone succinate compared to prednisolone is
due to strong hydrogen bonding interactions between the succinate group and water. -
False
The most stable pH range of a buffer containing weak acid and its salt is around its pKa
value. - True
Decision on the right dose and dosing frequency of a medication relies on a thorough
knowledge of its pharmacokinetics, which are quite predictable from patient to patient;
hence, standard dosage regimen works well for majority of patients, even for drugs that
have narrow therapeutic window. - False
WITH ANSWERS 2025/2026 GRADED A+
The colligative properties of a solution are related to the total number of solute particles
in the solution. - True
Bacteriostatic water for injection, USP, cannot be used for direct injection in neonates. -
True
The solubility of a solute is classified as a colligative property. - False
Elixirs usually contain 50 - 90% alcohol. - False
EDTA could be used as an antioxidant because it is easily oxidized. - False
Ophthalmic solutions are usually buffered to maintain pH, improve stability and/or
solubility of the drug substance, and/or maximize the effectiveness of the preservative. -
True
A surfactant must be an amphiphile with both a hydrophilic group and a hydrophobic
part. - True
The higher the HLB value of a surfactant, the more hydrophobic the surfactant is. -
False
Boric acid cannot be used in ophthalmic solutions as it can penetrate into the eye,
leading to a hypotonic situation for the eye. - False
Capsules of size 2 are larger than those of size 1. - False
Armour thyroid 1 grain is equivalent to 120 mg. - False
Readings are made at the top of the meniscus when one measures aqueous or
alcoholic liquids. - False
The rate of dissolution of a drug from a tablet can be increased by increasing the drug's
particle size. - False
An example of colloid IV solution is normal saline 0.9%. - True
Lipid membrane permeability of a molecule is related to its hydrophobicity. - True
The route of drug administration is dependent on the physical form of drug formulation. -
True
,The concentration unit % (w/v) is defined as milligrams of solute in 100 ml of solution. -
False
Among non-covalent interactions, hydrogen bonds are the strongest interactions. -
False
Cyclosporine readily dissolves in polyoxyethylated castor oil because of strong
electrostatic interactions. - False
According to the Bronsted-Lowry theory, an acid is defined as a substance which is
capable of accepting a proton. - False
The anti-diabetic drug glyburide is a weak acid with a pKa value of approximately 5.
Therefore, glyburide will be nearly 100% ionized in the blood at normal physiological
pH. - True
Buffers are always mixtures of weak acids and their conjugate bases or weak bases
and their conjugate acids. - True
Buffer capacity is determined by both the total buffer concentration and the
concentration ratio of conjugate base to weak acid or weak base to conjugate acid. -
True
The osmolarity of 1/2 Normal Saline is approximately 308 mOsm/L. - False
A patient has severe diarrhea, and his skin and mucous membranes are dry. The
patient could be given oral hypertonic solutions so that the body can become more
hydrated. - False
By definition, the V-value is the volume of sterile water to be added to dissolve 0.3 g of
a drug and make the solution isotonic. - True
Sterile membrane filtration of ophthalmic solutions under aseptic conditions is the
preferred method of sterilization. - True
Parabens could be used as antimicrobial preservatives in ophthalmic solutions. - True
The main mechanism of sodium bisulfite to be used as an antioxidant is that it can
directly reduce already oxidized drugs. - False
A solution that passes a pyrogen test will also pass a test for sterility. - False
One of the main purposes of adding one or more surfactants in dispersed systems is to
reduce interfacial tension and stabilize the system. - True
The higher the HLB value of a surfactant, the more hydrophobic the surfactant. - False
, Tween 80 is derived from Span 80 by adding polar polyoxyethylene groups to non-
esterified hydroxyls, and therefore Tween 80 is more hydrophilic than Span 80. - True
Approximately 15 mg of phenobarbital is to be dispensed when filling a prescription for
Phenobarbital 1/4 grain. - True
Porcelain pestle and glass mortar are the proper tools for reducing a coarse powder into
fine particle-sized powder because glass mortar provides a smooth surface for the
porcelain pestle. - False
Capsules of size 1 are smaller than those of size 3. - False
Sterile water for injection is considered as a hypotonic solution. When given IV, it will
cause cell lysis. - True
In lab, a USP standard sieve is used to obtain the desired particle size of the powder.
The larger the number of the sieve, the larger the particle size. - False
The number of dissolved solute particles in a solution is one of the factors that
determines colligative properties of the solution. - False
For an aqueous pharmaceutical solution at a very low drug concentration, its molarity is
close to its molality. - True
Cyclosporine readily dissolves in castor oil due to van der Waals interactions. - True
If heat of a solution in the process of solubilization of a particle drug (ΔH) is negative, an
increase in temperature will result in an increase in solubility of the drug. - False
Direction of osmosis is the same as the direction of osmotic pressure. - False
Salting out effect has a greater effect on aqueous solubility of electrolytes than non-
electrolytes. - False
The increased aqueous solubility of prenisolone succinate compared to prednisolone is
due to strong hydrogen bonding interactions between the succinate group and water. -
False
The most stable pH range of a buffer containing weak acid and its salt is around its pKa
value. - True
Decision on the right dose and dosing frequency of a medication relies on a thorough
knowledge of its pharmacokinetics, which are quite predictable from patient to patient;
hence, standard dosage regimen works well for majority of patients, even for drugs that
have narrow therapeutic window. - False
