b Focusb onbNursingbPharmacologyb 6ebInstructorb TestbBank
Chapter 1- Introduction to Drugs
b b b b
Abnursebworkingbinbradiologybadministersbiodinebtobabpatientbwhobisbhavingbabcomputed
b tomographyb(CT)bscan.bThebnursebworkingbonbtheboncologybunitbadministersb chemot
herapybtobpatientsbwhobhavebcancer.bAtbthebPublicbHealthbDepartment,babnurseb admini
stersbabmeasles-mumps-rubellab(MMR)bvaccinebtobab14-month-oldbchildbasba
routinebimmunization. bWhichbbranchbofbpharmacologybbestbdescribesbthebactionsbofball
1.
threebnurses?
A)
Pharmacoeconomics
B)
Pharmacotherapeutics
C)
Pharmacodynamics
D)
Pharmacokinetics
Ans: B
Feedback:
Pharmacologybisbthebstudybofbthebbiologicbeffectsbofbchemicals.bNursesbarebinvolvedbw
ithb clinicalbpharmacologyborbpharmacotherapeutics,bwhichbisbabbranchbofbpharmacolog
ybthatb dealsbwithbthebusesbofbdrugsbtobtreat,bprevent,bandbdiagnosebdisease.bThebradiolo
gybnursebisb administeringbabdrugbtobhelpbdiagnosebabdisease.bTheboncologybnursebisbad
ministeringba
drugbtobhelpbtreatbabdisease.bPharmacoeconomicsbincludesbanybcostsbinvolvedbinbdrug
b therapy.bPharmacodynamics binvolvesbhowbabdrugbaffectsbthebbodybandbpharmacokine
ticsb isbhowbthebbodybactsbonbthebbody.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarcotic, beveryb4
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b Focusb onbNursingbPharmacologyb 6ebInstructorb TestbBank
drugbtobhelpbtreatbabdisease.bPharmacoeconomicsbincludesbanybcostsbinvolvedbinbdrug
b therapy.bPharmacodynamics binvolvesbhowbabdrugbaffectsbthebbodybandbpharmacokine
ticsb isbhowbthebbodybactsbonbthebbody.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarcotic, beveryb4
hoursbasbneededbforbpainbinbabmotorbvehiclebaccidentbvictim.bThebnursebisbawarebthisbdrug
2.
hasbabhighbabusebpotential.bUnderbwhatbcategorybwouldbmorphinebbebclassified?
A)
SchedulebI
B)
SchedulebII
C)
SchedulebIII
D)
SchedulebIV
Ans: B
Feedback:
NarcoticsbwithbabhighbabusebpotentialbarebclassifiedbasbSchedulebIIbdrugsbbecausebofbsev
ereb dependencebliability.bSchedulebIbdrugsbhavebhighbabusebpotentialbandbnobacceptedb
medicalb use.bSchedulebIIIbdrugsbhavebablesserbabusebpotentialbthanbIIbandbanbacceptedb
medicalbuse.b SchedulebIVbdrugsbhaveblowbabusebpotentialbandblimitedbdependencebliab
ility.
WhenbinvolvedbinbphasebIIIbdrugbevaluationbstudies,bwhatbresponsibilities bwouldbthebnurse
3.
have?
A)
Workingbwithbanimalsbwhobarebgivenbexperimentalbdrugs
B)
Choosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugbstudy
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b Focusb onbNursingbPharmacologyb 6ebInstructorb TestbBank
A)
Workingbwithbanimalsbwhobarebgivenbexperimentalbdrugs
B)
Choosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugbstudy
C)
Monitoringbandbobservingbpatientsbcloselybforbadversebeffects
D)
Conductingbresearchbtobdeterminebeffectiveness bofbthebdrug
Ans: C
Feedback:
PhasebIIIbstudiesbinvolvebusebofbabdrugbinbabvastbclinicalbpopulationbinbwhichbpatientsb
areb askedbtobrecordbanybsymptomsbtheybexperiencebwhilebtakingbthebdrugs.bNursesb
maybbeb responsiblebforbhelpingbcollectbandbanalyzebthebinformationbtobbebsharedbwit
hbthebFoodb andbDrugbAdministrationb(FDA)bbutbwouldbnotbconductbresearchbindepen
dentlybbecauseb nursesbdobnotbprescribebmedications.bUsebofbanimalsbinbdrugbtestingbi
sbdonebinbtheb preclinicalbtrials.bSelectbpatientsbwhobarebinvolvedbinbphasebIIbstudies bt
obparticipatebin
studiesbwherebthebparticipantsbhavebthebdiseasebthebdrugbisbintendedbtobtreat.bThesebpati
entsb arebmonitoredbcloselybforbdrugbactionbandbadversebeffects.bPhasebIbstudiesbinvolve
bhealthyb humanbvolunteersbwhobarebusuallybpaidbforbtheirbparticipation.bNursesbmaybo
bservebforb adversebeffectsbandbtoxicity.
4.
Whatbconceptbisbconsideredbwhenbgenericbdrugsbarebsubstitutedbforbbrandbnamebdrugs?
A)
Bioavailability
B)
Criticalbconcentration
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A)
Bioavailability
B)
Criticalbconcentration
C)
Distribution
D)
Half-life
Ans: A
Feedback:
Bioavailabilitybisbthebportionbofbabdosebofbabdrugbthatbreachesbthebsystemicbcirculationb
andb isbavailablebtobactbonbbodybcells.bBindersbusedbinbabgenericbdrugbmaybnotbbebthebs
amebasb thosebusedbinbthebbrandbnamebdrug.bTherefore,bthebwaybthebbodybbreaksbdownb
andbusesbtheb drugbmaybdiffer,bwhichbmaybeliminatebabgenericbdrugbsubstitution. bCritical
bconcentrationbisb thebamountbofbabdrugbthatbisbneededbtobcausebabtherapeuticbeffectband
bshouldbnotbdifferb betweenbgenericbandbbrandbnamebmedications. bDistributionbisbthebph
asebofb pharmacokinetics,bwhichbinvolvesbthebmovementbofbabdrugbtobthebbody’sbtissues
bandbisbthe b samebinbgenericbandbbrandbnamebdrugs.bAbdrug’sbhalf-
lifebisbthebtimebitbtakesbforbtheb amountbofbdrugbtobdecreasebtobhalfbthebpeakblevel, bwhi
chbshouldbnotbchangebwhen
substitutingbabgenericbmedication.
Abnursebisbassessingbthebpatient’sbhomebmedicationbuse.bAfterblisteningbtobthebpatientblist
5.
currentbmedications, bthebnursebasksbwhatbprioritybquestion?
A)
“Dobyoubtakebanybgenericbmedications?”
B)
“Arebanybofbthesebmedicationsborphanbdrugs?”
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