520 Final Exam Questions With
Complete Solved Solutions.
overall acceptance of the dosage form regardless of the mode of it's administration - Answer
acceptability
overall acceptance of the taste, flavor, smell, dose, volume, or size and texture of a medicine to be
administered by mouth or to be swallowed - Answer palatability
t or f: the incidence of dysphagia increases with age - Answer t
t or f: if a patient is unable to take a solid oral dosage form, you will need to manipulate the mediation or
compound it - Answer f - may have to do this but you can also look into commercially available
alternatives
which organization posts real-time information about drug shortages? - Answer ASHP
what resources can you use to find alternative available dosage forms - Answer monographs (how
supplied/dosage forms)
guidelines
other reputable tertiary resources like clin pharm
t or f: a product that is available in a liquid formulation may still legally be extemporaneously
compounded if it is very expensive - Answer t - the law stating that extemporaneous compounding can
only be done if a product is not available can be extrapolated to mean that a product may not be
"available" due to costs prohibitions
define extemporaneous - Answer impromptu
prepared without a standard formula from an official compendium
prepared as required for a specific patient
,which is the best reference to use when determining information about extemporaneous formulations -
Answer ASHP 3rd edition extemporaneous formulations
35 year old female living with HIV presents to the infectious disease clinic with a two week history of
white plaques in her mouth and painful swallowing. She has a history of poor adherence to
antiretrovirals the doctor would like to prescribe fluconazole 100 milligrams daily for esophageal
Candidiasis and asks you, the clinical pharmacist, if tablets are the only option. You check the fluconazole
monograph:
solution, IV: 100mg, 200mg, 400mg
suspension reconstituted, oral: 10mg/mL, 40mg/mL
tablet, oral: 50mg, 100mg, 150mg, 200mg
Your recommendation is
A. she will just have to deal with swallowing tablets
B. only alternative is IV solution so she will have to be admitted to the hospital
C. the pharmacy can compound an extemporaneous suspension
D. prescribe 2.5 mL of the 40 mg/mL oral suspension daily to equate 100 mg
E. prescribe 100 mL of the 10 mg/mL oral suspension daily to equate 100 mg - Answer D
You are a pharmacist practicing in a community dispensing pharmacy. A parent drops off a prescription
for captopril oral solution for her five year old daughter. You discover the drug is only available in tablet
form. You will have to compound the oral solution. To learn how to prepare the solution you grab this
book from the pharmacy reference shelf
A. Teddy bear book
B. extemporaneous formulations
C. red book
D. yellow book - Answer B
t or f: atypical oral dosage forms are usually ones that are meant to be swallowed directly - Answer f -
not to be swallowed directly
t or f: if a tablet or capsule contents have poor taste, it cannot ever be made into an extemporaneous
formulation - Answer f - if no pK alteration expected, this is not always a complete contraindication
, t or f: if there is no pK alteration expected, drugs with an exposure risk can sometimes still be crushed
and given in extemporaneous solutions - Answer t - some times the healthcare worker/caregiver can
avoid risk by wearing gloves
what resource can be used to see if a drug can be crushed - Answer ISMP "do not crush" list
t or f: if a medication is not found on the ISMP "do not crush" list, it is safe to be crushed and
administered - Answer f - not an exhaustive list
You are a clinical pharmacist an ambulatory care general medicine clinic. A 79 year old male patient
presents as a walk-in stating he is having increasing difficulty swallowing his medications. You suggest he
make an appointment with the doctor for a full evaluation. In the meantime, you evaluate his medication
list to see if any can be crushed for easier administration. Medications with this/these general
property/properties are generally unsuitable for crushing:
A. Extended release formulation
B. enteric coated
C. mucosal irritant
D. all of the above - Answer D
A 65 year old male with a history of diabetes and hypertension is in the neurology intensive care unit for
observation following a cerebral vascular incident. He was given tissue plasminogen activator TPA
alteplase upon presentation to the emergency Department. He regained a significant amount of
functioning but is still experiencing dysphasia. The team asks you, the clinical pharmacist, if his
medications can be crushed and mixed with applesauce for administration. The first stop on your
literature search is the do not crush list. The organization that maintains this list is the:
A. Institute for safe medication practices
B. Food and Drug administration
C. United States pharmacopoeia
D. American Heart Association - Answer A
t or f: medications that require an acidic environment for full absorption can be given through a g - tube -
Answer t - cannot be given through something that bypasses the stomach like a j - tube
Complete Solved Solutions.
overall acceptance of the dosage form regardless of the mode of it's administration - Answer
acceptability
overall acceptance of the taste, flavor, smell, dose, volume, or size and texture of a medicine to be
administered by mouth or to be swallowed - Answer palatability
t or f: the incidence of dysphagia increases with age - Answer t
t or f: if a patient is unable to take a solid oral dosage form, you will need to manipulate the mediation or
compound it - Answer f - may have to do this but you can also look into commercially available
alternatives
which organization posts real-time information about drug shortages? - Answer ASHP
what resources can you use to find alternative available dosage forms - Answer monographs (how
supplied/dosage forms)
guidelines
other reputable tertiary resources like clin pharm
t or f: a product that is available in a liquid formulation may still legally be extemporaneously
compounded if it is very expensive - Answer t - the law stating that extemporaneous compounding can
only be done if a product is not available can be extrapolated to mean that a product may not be
"available" due to costs prohibitions
define extemporaneous - Answer impromptu
prepared without a standard formula from an official compendium
prepared as required for a specific patient
,which is the best reference to use when determining information about extemporaneous formulations -
Answer ASHP 3rd edition extemporaneous formulations
35 year old female living with HIV presents to the infectious disease clinic with a two week history of
white plaques in her mouth and painful swallowing. She has a history of poor adherence to
antiretrovirals the doctor would like to prescribe fluconazole 100 milligrams daily for esophageal
Candidiasis and asks you, the clinical pharmacist, if tablets are the only option. You check the fluconazole
monograph:
solution, IV: 100mg, 200mg, 400mg
suspension reconstituted, oral: 10mg/mL, 40mg/mL
tablet, oral: 50mg, 100mg, 150mg, 200mg
Your recommendation is
A. she will just have to deal with swallowing tablets
B. only alternative is IV solution so she will have to be admitted to the hospital
C. the pharmacy can compound an extemporaneous suspension
D. prescribe 2.5 mL of the 40 mg/mL oral suspension daily to equate 100 mg
E. prescribe 100 mL of the 10 mg/mL oral suspension daily to equate 100 mg - Answer D
You are a pharmacist practicing in a community dispensing pharmacy. A parent drops off a prescription
for captopril oral solution for her five year old daughter. You discover the drug is only available in tablet
form. You will have to compound the oral solution. To learn how to prepare the solution you grab this
book from the pharmacy reference shelf
A. Teddy bear book
B. extemporaneous formulations
C. red book
D. yellow book - Answer B
t or f: atypical oral dosage forms are usually ones that are meant to be swallowed directly - Answer f -
not to be swallowed directly
t or f: if a tablet or capsule contents have poor taste, it cannot ever be made into an extemporaneous
formulation - Answer f - if no pK alteration expected, this is not always a complete contraindication
, t or f: if there is no pK alteration expected, drugs with an exposure risk can sometimes still be crushed
and given in extemporaneous solutions - Answer t - some times the healthcare worker/caregiver can
avoid risk by wearing gloves
what resource can be used to see if a drug can be crushed - Answer ISMP "do not crush" list
t or f: if a medication is not found on the ISMP "do not crush" list, it is safe to be crushed and
administered - Answer f - not an exhaustive list
You are a clinical pharmacist an ambulatory care general medicine clinic. A 79 year old male patient
presents as a walk-in stating he is having increasing difficulty swallowing his medications. You suggest he
make an appointment with the doctor for a full evaluation. In the meantime, you evaluate his medication
list to see if any can be crushed for easier administration. Medications with this/these general
property/properties are generally unsuitable for crushing:
A. Extended release formulation
B. enteric coated
C. mucosal irritant
D. all of the above - Answer D
A 65 year old male with a history of diabetes and hypertension is in the neurology intensive care unit for
observation following a cerebral vascular incident. He was given tissue plasminogen activator TPA
alteplase upon presentation to the emergency Department. He regained a significant amount of
functioning but is still experiencing dysphasia. The team asks you, the clinical pharmacist, if his
medications can be crushed and mixed with applesauce for administration. The first stop on your
literature search is the do not crush list. The organization that maintains this list is the:
A. Institute for safe medication practices
B. Food and Drug administration
C. United States pharmacopoeia
D. American Heart Association - Answer A
t or f: medications that require an acidic environment for full absorption can be given through a g - tube -
Answer t - cannot be given through something that bypasses the stomach like a j - tube
