NSG520 Module 3: Inflammation &
Wound Healing (MSN-DE) Herzing
University Knowledge Test Questions
And Verified Answers.
The inflammatory response is a nonspecific response to local vasodilation (T or F) - Answer FALSE: The
inflammatory response is a nonspecific response to any tissue injury.
Chemical mediator released during the inflammatory response include which of the following?
1. Histamine and prostaglandins
2. Growth factors and cell enzymes
3. Macrophages and neutrophils
4. Albumin and fibrinogen - Answer Histamine and prostaglandins
Pain and increased capillary permeability are the result from the release of chemical mediators following
a moderate burn injury. T or F. - Answer TRUE
Migration of leukocytes to the area is the last step in the inflammatory response after a tissue injury. T or
F. - Answer TRUE
Macrophages are nonspecific agents that protect uninfected cells against viruses. T or F. - Answer FALSE
The process of phagocytosis involves which of the following?
1. Shift of fluid and protein out of capillaries
2. Movement of erythrocytes through the capillary wall
3. Formation of a fibrin mesh around the infected area
4. Ingestion of foreign material and cell debris by leukocytes - Answer Ingestion of foreign material and
cell debris by leukocytes
,_______ inflammation occurs rapidly in reaction to cell injury. - Answer ACUTE
A polyp is a small mass of cells with a necrotic center and covered by connective tissue. T or F. - Answer
FALSE (a granuloma is a small mass of cells with a necrotic center and covered by connective tissue)
The body's _____ (first, second, or third) line of immune defense is nonspecific, or a general defense
mechanism, including a mechanical barrier such as the skin or mucous membrane that blocks entry of
bacteria or harmful substances into the tissues - Answer FIRST
The body's second line of defense includes the nonspecific processes of phagocytosis and inflammation.
T or F. - Answer TRUE
The body's second line of defense is the specific mechanism that provides protection by stimulating the
production of unique antibodies or sensitized lymphocytes following exposure to specific substances. T
or F. - Answer FALSE
______ arrive first to the site of cell injury, are the most numerous of all WBCs, and are part of the innate
immune system (hint: type of WBC) - Answer Neutrophils
Allergic Responses: antibodies of the immunoglobulin E (IgE) class bind to basophil receptors, causing
them to release their stores of inflammatory chemicals, including histamine, serotonin, and leukotrienes
(QUESTION: What type of WBC responds?) - Answer Basophils (Remember: Basophils respond to
basophil receptors!)
What type of WBC is active in larger parasitic infections, allergy responses, and some cancers? - Answer
Eosinophil (THINK: Old MacDonald had a farm; EIEIO - E is for eosinophil and there are PARASITES on the
farm!)
Largest WBC is ______; these differentiates into macrophages that clean up cellular debris in the
inflammatory process - Answer Monocytes (THINK: Mmmonocytes differentiate into Mmmacrophages -
both start with letter M)
Fatigue, anorexia, and mild fever are systemic effects of severe inflammation. T or F. - Answer TRUE
, Which of the following statements applies to fever? CHOOSE ONE.
1. It is caused by a signal to the thalamus
2. Viral infection is usually present
3. It results from release of pyrogens into circulation
4. Heat-loss mechanisms have been stimulated - Answer It results from release of pyrogens into
circulation (THINK: anti-PYRETICS treat fever)
An increased heart rate is a mechanism to bring an elevated body temperature down to the normal
level.
True/False - Answer FALSE: General cutaneous vasodilation is a mechanism to bring an elevated body
temperature down to the normal level.
Patients taking glucocorticoids for long periods of time are likely to develop all of the following except?
1. Opportunistic infections
2. Decreased bone density
3. Wasting of skeletal muscle
4. Increased leukocyte production - Answer Increased leukocyte production
Tylenol is an anti-inflammatory agent.
True/False - Answer FALSE (Tylenol is an antipyretic and analgesic)
Systemic manifestations of an inflammatory response include which of the following? CHOOSE ONE.
1. Edema and erythema
2. Pain and tenderness
3. Area of necrosis and loss of function
4. Fever and malaise - Answer Fever & malaise
Which of the following statements is true about COX-1 inhibitors?
1. "COX-1 inhibitors protect against myocardial infarction and stroke."
2."COX-1 inhibitors reduce fever."
Wound Healing (MSN-DE) Herzing
University Knowledge Test Questions
And Verified Answers.
The inflammatory response is a nonspecific response to local vasodilation (T or F) - Answer FALSE: The
inflammatory response is a nonspecific response to any tissue injury.
Chemical mediator released during the inflammatory response include which of the following?
1. Histamine and prostaglandins
2. Growth factors and cell enzymes
3. Macrophages and neutrophils
4. Albumin and fibrinogen - Answer Histamine and prostaglandins
Pain and increased capillary permeability are the result from the release of chemical mediators following
a moderate burn injury. T or F. - Answer TRUE
Migration of leukocytes to the area is the last step in the inflammatory response after a tissue injury. T or
F. - Answer TRUE
Macrophages are nonspecific agents that protect uninfected cells against viruses. T or F. - Answer FALSE
The process of phagocytosis involves which of the following?
1. Shift of fluid and protein out of capillaries
2. Movement of erythrocytes through the capillary wall
3. Formation of a fibrin mesh around the infected area
4. Ingestion of foreign material and cell debris by leukocytes - Answer Ingestion of foreign material and
cell debris by leukocytes
,_______ inflammation occurs rapidly in reaction to cell injury. - Answer ACUTE
A polyp is a small mass of cells with a necrotic center and covered by connective tissue. T or F. - Answer
FALSE (a granuloma is a small mass of cells with a necrotic center and covered by connective tissue)
The body's _____ (first, second, or third) line of immune defense is nonspecific, or a general defense
mechanism, including a mechanical barrier such as the skin or mucous membrane that blocks entry of
bacteria or harmful substances into the tissues - Answer FIRST
The body's second line of defense includes the nonspecific processes of phagocytosis and inflammation.
T or F. - Answer TRUE
The body's second line of defense is the specific mechanism that provides protection by stimulating the
production of unique antibodies or sensitized lymphocytes following exposure to specific substances. T
or F. - Answer FALSE
______ arrive first to the site of cell injury, are the most numerous of all WBCs, and are part of the innate
immune system (hint: type of WBC) - Answer Neutrophils
Allergic Responses: antibodies of the immunoglobulin E (IgE) class bind to basophil receptors, causing
them to release their stores of inflammatory chemicals, including histamine, serotonin, and leukotrienes
(QUESTION: What type of WBC responds?) - Answer Basophils (Remember: Basophils respond to
basophil receptors!)
What type of WBC is active in larger parasitic infections, allergy responses, and some cancers? - Answer
Eosinophil (THINK: Old MacDonald had a farm; EIEIO - E is for eosinophil and there are PARASITES on the
farm!)
Largest WBC is ______; these differentiates into macrophages that clean up cellular debris in the
inflammatory process - Answer Monocytes (THINK: Mmmonocytes differentiate into Mmmacrophages -
both start with letter M)
Fatigue, anorexia, and mild fever are systemic effects of severe inflammation. T or F. - Answer TRUE
, Which of the following statements applies to fever? CHOOSE ONE.
1. It is caused by a signal to the thalamus
2. Viral infection is usually present
3. It results from release of pyrogens into circulation
4. Heat-loss mechanisms have been stimulated - Answer It results from release of pyrogens into
circulation (THINK: anti-PYRETICS treat fever)
An increased heart rate is a mechanism to bring an elevated body temperature down to the normal
level.
True/False - Answer FALSE: General cutaneous vasodilation is a mechanism to bring an elevated body
temperature down to the normal level.
Patients taking glucocorticoids for long periods of time are likely to develop all of the following except?
1. Opportunistic infections
2. Decreased bone density
3. Wasting of skeletal muscle
4. Increased leukocyte production - Answer Increased leukocyte production
Tylenol is an anti-inflammatory agent.
True/False - Answer FALSE (Tylenol is an antipyretic and analgesic)
Systemic manifestations of an inflammatory response include which of the following? CHOOSE ONE.
1. Edema and erythema
2. Pain and tenderness
3. Area of necrosis and loss of function
4. Fever and malaise - Answer Fever & malaise
Which of the following statements is true about COX-1 inhibitors?
1. "COX-1 inhibitors protect against myocardial infarction and stroke."
2."COX-1 inhibitors reduce fever."
