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DPT 708 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED

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DPT 708 FINAL EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED motor unit LMN and all the muscle fibers it innervates afferent neurons sensory neurons traveling to spinal cord/brain efferent neurons motor neurons sending signal to muscles what do muscle spindles and golgi tendon organs provide speed and size of muscle length change muscle position muscle tension limb orientation with respect to gravity (proprioception) membrane potential concentration of difference of ions across membranes can create potential What is the resting membrane potential? [Na+] outside [Na+] inside more permeable to movement of K+ can vary from -20 to -200 mV nerst potential Na+ diffuses into cell making the potential (-) and more (+) on the inside - membrane potential rises high enough to block further diffusion of Na+ = +60mV inside cell what does it mean for nerve and muscle cells to be excitable they are capable of generating rapid electrochemical impulses at membranes how do other cells control cell function with membrane potential they use local changes in MP and signal downstream within the cell membrane potential unequal distribution of ions across membrane electrical dipole layer charge along membrane outside is (+) and inside is (-) due to ratio of ions outside vs inside the cell RMP of large nerve cells -80 to -90 mV the electric potential inside the cell is 80 to 90mV more negative than the charge outside the cell what is the origin of the RMP

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DPT 708 FINAL EXAM QUESTIONS AND ANSWERS WITH

COMPLETE SOLUTIONS VERIFIED

motor unit

LMN and all the muscle fibers it innervates

afferent neurons

sensory neurons traveling to spinal cord/brain

efferent neurons

motor neurons sending signal to muscles

what do muscle spindles and golgi tendon organs provide

speed and size of muscle length change



muscle position



muscle tension



limb orientation with respect to gravity (proprioception)

membrane potential

concentration of difference of ions across membranes can create potential

What is the resting membrane potential?

[Na+] outside > [Na+] inside

,more permeable to movement of K+



can vary from -20 to -200 mV

nerst potential

Na+ diffuses into cell making the potential (-) and more (+) on the inside -> membrane

potential rises high enough to block further diffusion of Na+ = +60mV inside cell

what does it mean for nerve and muscle cells to be excitable

they are capable of generating rapid electrochemical impulses at membranes

how do other cells control cell function with membrane potential

they use local changes in MP and signal downstream within the cell

membrane potential

unequal distribution of ions across membrane

electrical dipole layer

charge along membrane



outside is (+) and inside is (-) due to ratio of ions outside vs inside the cell

RMP of large nerve cells

-80 to -90 mV



the electric potential inside the cell is 80 to 90mV more negative than the charge outside

the cell

what is the origin of the RMP

, diffusion of K+ out and minimal Na+ in (leaky channels)



Na+/K+ pump

what does Na+/K+ pump do

maintains concentration gradient by rapid movement of Na+ to the outside of the cell to

make the inside more (-)



3 Na+ OUT for every 2 K+ IN



more (+) ions pumped out develops a (-) charge along the inside of the cell membrane

RMP of Na+ only

+65 mV

RMP of K+ only

-94 mV

action potentials

rapid changes in local membrane potential that spread rapidly along nerve

membrane threshold

potential it takes to activate voltage gated sodium channels to discharge AP across

entire cell

3 stages of APs

resting = RMP is -90 mV (polarized)



depolarization: inside becomes less (-) Na+/K+ pump turns on

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