MMSC 423 Hematology Final Exam
Questions & Answers 2025/2026
a prolonged PT, APT, TT, undetectable fibrinogen by the class method would be seen in -
ANSWERSafibrinogenemia
in this sex-linked recessive disorder, a common clinical finding is hemarthrosis, normal platelet
count, normal RIPA - ANSWERShemophilia A
In this type of vWD, pt count is normal, PTT is prolonged, vwF antigen is very low or absent,
RIPA is absent and all vWF multimers are absent: - ANSWERStype 3
which of the following is recognized as viable treatment for TTP - ANSWERSplasma exchange
all of the following may be seen in HUS - ANSWERSdecreased reticulocyte count
all of the following are associated with HELLP syndrome except: - ANSWERSabsence of
schistocytes
In this rare recessive disorder, patients are missing the radius bone and present with an elevated
WBC count and decreased platelet count - ANSWERSTAR syndrome
In this syndrome platelets are lacking dense granules, and present with oculocutaneous
albinism, bleeding gums, and excessive bleeding after surgery: - ANSWERShermansky-pullak
which TEG parameter should let the clinical know a platelet transfusion is indicated -
ANSWERSdecreased MA
,in this autosomal disorder clot extraction is abnormal - ANSWERSglanzmanns thromboasthenia
what is considered normal range for bleeding time - ANSWERS2-9 minutes
which of the following disorders charactered by lack of alpha granules - ANSWERSgray platelet
test measured for platelet plug to occlude the area - ANSWERSPFA-100
When running TEG, what reagent will be unemployed in the test system for a pt on
unfractionated heparin? - ANSWERSHeparinase
all of the following coagulation factor are measured in the prothrombin complex time test
except - ANSWERSFactor 13 (XIII)
what does ISI stand for - ANSWERSinternational sensitivity index
all of the following are measured by the APTT except - ANSWERSFactor 7 (VII)
This screening test for factor V involves adding a standard amount of activated protein C for
both patient plasma and normal plasma - ANSWERSAPTT
what test is elevated in uncompensated DIC - ANSWERSd-dimer
light transmittance is increased in platelet aggregation studies where the platelet agonist
employed is ADP - ANSWERStrue
,Patients who have deficiency in GP1B have a deficiency in adhesion - ANSWERStrue
oral anticoagulant - ANSWERSvitamin k
which of the following is decreased in uncompensated DIC - ANSWERSfibrinogen
DDVAP is an effective treatment of - ANSWERSvWD type 1
what would mixing studies reveal in a patient with an inhibitor to factor VIII - ANSWERSAPPTT
would not correct with absorbed plasma or normal plasma
which of the following tests is increased in a patient with severe hemophilia A - ANSWERSPTT
a patient presents with a PT of 17 seconds, PTT of 31, and TT of 16, what factor deficiency is
most likely - ANSWERSVII
what subtype of vWD gives a positive response - ANSWERS2b
what molecule does unfractionated heparin bind to in precipitating its anticoagulation -
ANSWERSantithrombin
what efficacy would IVIG serve in treatment of ITP - ANSWERSkeeps IgG coated platelets in
circulation
Which of the following is disorder of aggregation? - ANSWERSglanzmanns thromboasthenia
A female patient, 45 yrs old, comes into the Emergency Room complaining of bruises on their
forearm and epistaxis. Lab results showed a PT of 16 seconds, APTT of 30 seconds, platelet
, count of 140,000/µL, and hemoglobin of 14.4 g/dL. A mixing study was done to try and correct
the PT with both aged serum and adsorbed plasma. With aged serum in the mixing study with
patient plasma, the PT was 11 seconds; however with adsorbed plasma it was 16 seconds. What
could be the factor deficiency? - ANSWERSFVII
this abnormal red cell can be found in a patient with DIC - ANSWERSschistocyte
which of the following is vitamin k antagonist - ANSWERSWarfarin
what is the target anticoagulant mechanism of unfractionated heparin - ANSWERSthrombin
inhibition
what coagulation factor is the first to decrease when the patient place on warfarin -
ANSWERSVII
what of the following can reverse affects of warfarin - ANSWERSvitamin k
blood to anticoagulant ratio - ANSWERS9:1
what test is usually employed in detecting the presence of lupus anticoagulant - ANSWERSdilute
russels viper test
which of the following test would be unaffected by the presence of heparin to patient plasma -
ANSWERSretipilase time
the extrinsic pathway of coagulation if monitored by - ANSWERSprothrombin
what anticoagulant is used to collect patient blood specimens in coagulation/hemosstasis
testing - ANSWERSsodium citrate
Questions & Answers 2025/2026
a prolonged PT, APT, TT, undetectable fibrinogen by the class method would be seen in -
ANSWERSafibrinogenemia
in this sex-linked recessive disorder, a common clinical finding is hemarthrosis, normal platelet
count, normal RIPA - ANSWERShemophilia A
In this type of vWD, pt count is normal, PTT is prolonged, vwF antigen is very low or absent,
RIPA is absent and all vWF multimers are absent: - ANSWERStype 3
which of the following is recognized as viable treatment for TTP - ANSWERSplasma exchange
all of the following may be seen in HUS - ANSWERSdecreased reticulocyte count
all of the following are associated with HELLP syndrome except: - ANSWERSabsence of
schistocytes
In this rare recessive disorder, patients are missing the radius bone and present with an elevated
WBC count and decreased platelet count - ANSWERSTAR syndrome
In this syndrome platelets are lacking dense granules, and present with oculocutaneous
albinism, bleeding gums, and excessive bleeding after surgery: - ANSWERShermansky-pullak
which TEG parameter should let the clinical know a platelet transfusion is indicated -
ANSWERSdecreased MA
,in this autosomal disorder clot extraction is abnormal - ANSWERSglanzmanns thromboasthenia
what is considered normal range for bleeding time - ANSWERS2-9 minutes
which of the following disorders charactered by lack of alpha granules - ANSWERSgray platelet
test measured for platelet plug to occlude the area - ANSWERSPFA-100
When running TEG, what reagent will be unemployed in the test system for a pt on
unfractionated heparin? - ANSWERSHeparinase
all of the following coagulation factor are measured in the prothrombin complex time test
except - ANSWERSFactor 13 (XIII)
what does ISI stand for - ANSWERSinternational sensitivity index
all of the following are measured by the APTT except - ANSWERSFactor 7 (VII)
This screening test for factor V involves adding a standard amount of activated protein C for
both patient plasma and normal plasma - ANSWERSAPTT
what test is elevated in uncompensated DIC - ANSWERSd-dimer
light transmittance is increased in platelet aggregation studies where the platelet agonist
employed is ADP - ANSWERStrue
,Patients who have deficiency in GP1B have a deficiency in adhesion - ANSWERStrue
oral anticoagulant - ANSWERSvitamin k
which of the following is decreased in uncompensated DIC - ANSWERSfibrinogen
DDVAP is an effective treatment of - ANSWERSvWD type 1
what would mixing studies reveal in a patient with an inhibitor to factor VIII - ANSWERSAPPTT
would not correct with absorbed plasma or normal plasma
which of the following tests is increased in a patient with severe hemophilia A - ANSWERSPTT
a patient presents with a PT of 17 seconds, PTT of 31, and TT of 16, what factor deficiency is
most likely - ANSWERSVII
what subtype of vWD gives a positive response - ANSWERS2b
what molecule does unfractionated heparin bind to in precipitating its anticoagulation -
ANSWERSantithrombin
what efficacy would IVIG serve in treatment of ITP - ANSWERSkeeps IgG coated platelets in
circulation
Which of the following is disorder of aggregation? - ANSWERSglanzmanns thromboasthenia
A female patient, 45 yrs old, comes into the Emergency Room complaining of bruises on their
forearm and epistaxis. Lab results showed a PT of 16 seconds, APTT of 30 seconds, platelet
, count of 140,000/µL, and hemoglobin of 14.4 g/dL. A mixing study was done to try and correct
the PT with both aged serum and adsorbed plasma. With aged serum in the mixing study with
patient plasma, the PT was 11 seconds; however with adsorbed plasma it was 16 seconds. What
could be the factor deficiency? - ANSWERSFVII
this abnormal red cell can be found in a patient with DIC - ANSWERSschistocyte
which of the following is vitamin k antagonist - ANSWERSWarfarin
what is the target anticoagulant mechanism of unfractionated heparin - ANSWERSthrombin
inhibition
what coagulation factor is the first to decrease when the patient place on warfarin -
ANSWERSVII
what of the following can reverse affects of warfarin - ANSWERSvitamin k
blood to anticoagulant ratio - ANSWERS9:1
what test is usually employed in detecting the presence of lupus anticoagulant - ANSWERSdilute
russels viper test
which of the following test would be unaffected by the presence of heparin to patient plasma -
ANSWERSretipilase time
the extrinsic pathway of coagulation if monitored by - ANSWERSprothrombin
what anticoagulant is used to collect patient blood specimens in coagulation/hemosstasis
testing - ANSWERSsodium citrate
