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A short class notes on Immune Sytem

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Comprehensive notes on the immune system, covering both innate and adaptive immunity, their components, and functions. Includes explanations of key cells like T-cells, B-cells, and macrophages, along with processes such as inflammation and antigen-antibody interaction. Simplified discussions on common immune disorders like autoimmune diseases and allergies are also included. These notes are well-organized, easy to understand, and perfect for quick reviews or exam preparation. Ideal for nursing or medical students, with diagrams and flowcharts to enhance learning. Available in digital PDF or print format at an affordable price.

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Immune system These cells surround and
absorb pathogens and
 Our immune system is essential for break them down,
our survival. Without an immune effectively eating them.
system, our bodies would be open to  Neutrophils
attack from bacteria, viruses,  These are the most
parasites, and more. common type of
 It is our immune system that keeps phagocyte and tend
us healthy as we drift through a sea to attack bacteria.
of pathogens. Numerous
 If the immune system encounters a  Monocytes
pathogen, for instance, a bacterium,  These are the largest
virus, or parasite, it mounts a so- type and have
called immune response. several roles.
 Macrophages
 These patrol for
White Blood Cells pathogens and also
 White blood cells are also called remove dead and
leukocytes. Greek; leucko-white and dying cells.
cyte- cell  Mast cells
 They circulate in the body in blood  They have many jobs,
vessels and the lymphatic vessels including helping to
that parallel the veins and arteries. heal wounds and
 A type of blood cell that is made in defend against
the bone marrow and found in the pathogens.
blood and lymph tissue.
 White blood cells are part of the 2. Lymphocytes
body's immune system.  Help the body to remember
previous invaders and
 WBC's are stored in different recognize them if they
places in the body come back to attack again.
 Our white blood cells are  Lymphocytes begin their
stored in different places in life in bone marrow. Some
the body, which are referred to stay in the marrow and
as Lymphoid organs. The develop into B
organs and tissues of the lymphocytes (B cells),
immune system are referred to others head to the thymus
as lymphoid and become T lymphocytes
 Thymus- A gland (T cells). These two cell
between the lungs and types have different roles
just below the neck  B and T cells are the 2
 Spleen- An organ that major types of
filters the blood. It sits lymphocytes and belong to
in the upper left of the same family which is the
abdomen. Hemocytoblast/
 Bone marrow - Found in Multipotential (many
the center of the bones, forms) Hematopoietic Stem
it also produces red Cells
blood cells. Myelos is
Greek for “marrow”  B Lymphocytes
 Lymph nodes- Small  They produce antibodies
glands positioned and help alert the T
throughout the body, lymphocytes, Antibodies
linked by lymphatic attach to a specific antigen
vessels. Kulani and make it easier for the
immune cells to destroy the
antigen.
2 main types of Leukocyte:  Shields of the immunity
1. Phagocytes (Immunoglobulins)
 Role

,  Once B lymphocytes have been extensively studied
spot the antigen, they in CD8+ T cells, very little is
begin to secrete known about NK cells.
antibodies (antigen is
short for "antibody  Regulatory T cells
generators").  Suppress your immunity or
 Antibodies are special increase the immunity.
proteins that lock on to Prevent auto immune
specific antigens. disease
 Each B cell makes one
specific antibody. ANTIBODIES (GAMED)
 For instance, one might  Part of a large family of chemicals
make an antibody called immunoglobulins, which
against the bacteria play many roles in the immune
that cause pneumonia, response:
and another might GAMED → mnemonic
recognize the common  IgG
cold virus.  Most common antibody and
marks microbes so other cells
can recognize and deal with
 T lymphocytes them.
 They destroy compromised  Attached in memory B- cell
cells in the body and help  If you are positive IgG during
alert other leukocytes. They the antigen test definitely it is
also release chemicals, known an old infection
as cytokines, which control  Major antibody secreted
the entire immune response during the secondary
 The attackers response; neutralizes antigens
and promotes their
phagocytosis and activates
Distinct Types complement
 Helper T cells (Th cells / CD4)
 They coordinate the immune  The most abundant class of
response. Some communicate antibodies in the bloodstream and
with other cells, and some tissues (If you are old)
stimulate B cells to produce  It provides long-lasting immunity
more antibodies. Others against Infections and can cross the
attract more T cells or cell- placenta, offering passive Immunity
eating phagocytes. to the fetus.
 IgG antibodies are involved in
 Killer T cells (CD8+ cytotoxic T opsonization (marking pathogens for
lymphocytes) destruction by phagocytes) and
 As the name suggests, these T neutralization of toxins.
cells attack other cells. They
are particularly useful for  IgM
fighting viruses. They work by  Is expert at killing bacteria
recognizing small parts of the  M- Malaki (Very large
virus on the outside of Immunoglobulin)
infected cells and destroy  If you are positive in IgM
the infected cells. during the antigen test
Phagocytose therefore it is the first/new
 CD8+ T cells and NK cells are infection
both cytotoxic effector cells of  First antibody secreted during
the immune system, but the the primary immune response;
recognition, specificity, promotes agglutination and
sensitivity, and memory precipitation reactions and
mechani activates complement

 sms are drastically different.  The first antibody class produced in
While many of these topics response to an infection.

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