FINAL BIOL3003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE

FINAL BIOL3003 EXAM QUESTIONS AND ANSWERS

WITH COMPLETE SOLUTIONS VERIFIED LATEST UPDATE


Function of CD8 Tcell

Kill virally infected cell

Functions of CD4 Th1 cell

Activate macrophage and help B cells produce antibody

Functions of CD4 Th2 cells

Help B cells switch antibodies (especially to IgE)

Functions of Th17 cells

Enhance neutrophile response

Promote epithelial barrier integrity

Functions of TfH cells

Help B cells to perform isotype switching

Help B cells produce antibody

CD4 reg cells

Suppress T cells

Pathogens targeted by CD8 T cells

Viruses, and some intracellular bacteria

Pathogens targeted by CD4 Th1 cells

Microbes that persist in macrophage vesicles and extracellular bacteria

Pathogens targeted by CD4 Th2 cells

, Helminth parasites

Pathogens targeted by CD4 Th17 cells

Fungi and klebsiella pneumoniae (an intestinal bacteria)

Natural killer T cells

COME

MAIT cells

mucosal associated invariant T cells

Recognised by mucosal associated invariant T cells

Vitamin B metabolites

Gamma delta T cells

COME BACK

Recognised by iNKT cells

Glycolipids loaded in CD1d

Receptor of a iNKT cell

Semi invariant (alpha chain is conserved, beta chain is variable)

5 features of MAIT cells

1. TCR alpha chain is highly conserved

2. Recognise microbial Vitamin B metabolites presented on MR1

3. Reside in mucosal compartments, liver and blood

4. Immunity to bacteria and yeast

5. Produce IFN-g, TNF-a, and IL-17

5 features of iNKT cells