Summary THE NUCLEUS

The cytosol is the largest single cellular compartment (a little
>50% of cell volume). It can be described as a concentrated
aqueous gel. It is the main site of protein synthesis, protein
degradation, and intermediary metabolism.




• Cytoplasm + nucleus have distinct functions, but work in concert to
maintain cellular viability

,The cytosol is the largest single cellular compartment (a little
>50% of cell volume). It can be described as a concentrated
aqueous gel. It is the main site of protein synthesis, protein
degradation, and intermediary metabolism.
• Intermediary metabolism involves the synthesis and degradation of small molecules to
provide the building blocks for biomolecules

• Molecules in the cytoplasmic matrix include
• Inorganic solutes
• Intermediate metabolites
• Carbohydrates
• Lipids
• Proteins
• RNAs


• Solute concentration in the matrix is tightly controlled and influences the rate of metabo
activity

,ANATOMY OF THE NUCLEUS
Dr. N. Mutuku

, IN THIS LECTURE WE WILL DISCUSS THE
STRUCTURE OF THE FOLLOWING AND ITS
ROLE IN THEIR FUNCTION:
• The eukaryote cell nucleus
• The nuclear envelope
• Chromatin
• The nucleolus
• The nuclear cytoskeleton