Advanced Human Bioscience (HUBS1416) is an in-depth exploration of human biology, integrating
advanced concepts from physiology, molecular biology, biochemistry, immunology, genetics, and
pathology. This course is essential for students in biomedical sciences, health sciences, and related
fields, providing them with a strong foundation in the biological mechanisms underlying human health
and disease.
1. Cellular and Molecular Biology
This module explores the fundamental building blocks of life, focusing on cellular structures, functions,
and molecular interactions.
Key Concepts:
Cell Structure & Function: Detailed study of eukaryotic cells, organelles, and their specialized
functions.
DNA & RNA: Mechanisms of replication, transcription, and translation, including the regulation
of gene expression.
Cell Cycle & Division: Phases of the cell cycle, mitosis, meiosis, and their regulatory checkpoints.
Apoptosis & Necrosis: Programmed cell death vs. accidental cell death and their implications in
disease.
Cell Communication: Signal transduction pathways, including G-protein coupled receptors and
second messengers.
2. Human Physiology and Homeostasis
This module focuses on how different organ systems work together to maintain homeostasis.
Key Concepts:
Homeostatic Mechanisms: Negative and positive feedback loops regulating body functions.
Nervous System Regulation: Structure and function of the central (CNS) and peripheral nervous
systems (PNS).
Autonomic Nervous System: Sympathetic and parasympathetic responses.
Endocrine System: Hormonal signaling and regulation of metabolism, growth, and stress
responses.
Cardiovascular & Respiratory Integration: Blood circulation, oxygen transport, and acid-base
balance.