C HAPTER 6: M ICROBIAL R EGULATORY
S YSTEMS
Test Bank for Brock Biology of Microorganism 16th Edition by Michael T.
Madigan
6.1 Multiple Choice Questions
1. Regulation of enz yme activit y occurs
A) at the start of transcription.
B) at the start of translation.
C) posttranslationall y.
D) at any point on the enzymatic production pathway.
2. A protein region with a specific function and structure is called a
A) conserved site.
B) domain.
C) locale.
D) motif.
3. Transcriptional regulators bind most f requentl y at the site of DNA.
A) major groove
B) minor groove
C) histone complex
D) primary supercoil
4. Which t ype of regulator(s) specificall y binds to operator regions of DNA?
A) activators
B) activators and inducers
, C) repressors
D) repressors and corepressors
5. The function of a kinase is
A) methylation.
B) response regulation.
C) phosphorylation.
D) gl ycosylation.
6. Infection by the foodborne pathogen E coli O157:H7 involves all of the
following host and pathogen signaling molecules EXCEPT
A) AI-3.
B) MCP.
C) epinephrine.
D) norepinephrine.
7. Regulatory proteins
A) are influenced by small molecules.
B) bind to specific DNA sites.
C) regulate transcription.
D) regulate transcription, bind specific DNA sites, and can be influenced
by small molecules.
8. The lac operon is an example of _______ control in which the presence of
an ______ is required for transcription to occur.
A) negative / activator
B) negative / inducer
C) positive / activator
D) positive / inducer
9. Enz yme induction occurs
A) when the substrate is present.
, B) when the organism is environment all y stressed.
C) continuousl y.
D) when the substrate is depleted.
10.Considering the catabolite repression mechanism, which observation
would make you suspect it IS occurring?
A) CRP bound to promoter sites
B) elevated levels of transcripts for maltose and sucrose catabolism
C) relativel y low intracellular cyclic AMP levels
D) RNA pol ymerase bound to biosynthetic promoter sequences
11.Which of the following do NOT bind to the promoter sequence during
regulation?
A) activators
B) inducers
C) repressors
D) None of these bind dire ctl y to the promoter sequence.
12.Cyclic AMP is synthesized from ATP by an enz yme called _____ which is
involved in ______.
A) adenylate cyclase / catabolite repression
B) adenylate cyclase / transcriptional activation
C) cAMP receptor protein (CRP) synthase / ca tabolite repression
D) cAMP receptor protein (CRP) synthase / transcriptional activation
13.In negative control of transcription by the lac operon, how does the
presence of an inducer affect transcription?
A) The inducer binds to the operator.
B) The inducer does not bind to the operator.
C) The inducer causes the repressor to bind to the operator.
D) The inducer prevents the repressor from binding to the operator.
S YSTEMS
Test Bank for Brock Biology of Microorganism 16th Edition by Michael T.
Madigan
6.1 Multiple Choice Questions
1. Regulation of enz yme activit y occurs
A) at the start of transcription.
B) at the start of translation.
C) posttranslationall y.
D) at any point on the enzymatic production pathway.
2. A protein region with a specific function and structure is called a
A) conserved site.
B) domain.
C) locale.
D) motif.
3. Transcriptional regulators bind most f requentl y at the site of DNA.
A) major groove
B) minor groove
C) histone complex
D) primary supercoil
4. Which t ype of regulator(s) specificall y binds to operator regions of DNA?
A) activators
B) activators and inducers
, C) repressors
D) repressors and corepressors
5. The function of a kinase is
A) methylation.
B) response regulation.
C) phosphorylation.
D) gl ycosylation.
6. Infection by the foodborne pathogen E coli O157:H7 involves all of the
following host and pathogen signaling molecules EXCEPT
A) AI-3.
B) MCP.
C) epinephrine.
D) norepinephrine.
7. Regulatory proteins
A) are influenced by small molecules.
B) bind to specific DNA sites.
C) regulate transcription.
D) regulate transcription, bind specific DNA sites, and can be influenced
by small molecules.
8. The lac operon is an example of _______ control in which the presence of
an ______ is required for transcription to occur.
A) negative / activator
B) negative / inducer
C) positive / activator
D) positive / inducer
9. Enz yme induction occurs
A) when the substrate is present.
, B) when the organism is environment all y stressed.
C) continuousl y.
D) when the substrate is depleted.
10.Considering the catabolite repression mechanism, which observation
would make you suspect it IS occurring?
A) CRP bound to promoter sites
B) elevated levels of transcripts for maltose and sucrose catabolism
C) relativel y low intracellular cyclic AMP levels
D) RNA pol ymerase bound to biosynthetic promoter sequences
11.Which of the following do NOT bind to the promoter sequence during
regulation?
A) activators
B) inducers
C) repressors
D) None of these bind dire ctl y to the promoter sequence.
12.Cyclic AMP is synthesized from ATP by an enz yme called _____ which is
involved in ______.
A) adenylate cyclase / catabolite repression
B) adenylate cyclase / transcriptional activation
C) cAMP receptor protein (CRP) synthase / ca tabolite repression
D) cAMP receptor protein (CRP) synthase / transcriptional activation
13.In negative control of transcription by the lac operon, how does the
presence of an inducer affect transcription?
A) The inducer binds to the operator.
B) The inducer does not bind to the operator.
C) The inducer causes the repressor to bind to the operator.
D) The inducer prevents the repressor from binding to the operator.
