What are the four examples of intracellular accumulations
abnormal metabolism, defect in protein folding or transport, lack of enzymes, and
ingestion of indigestible materials
Atrophy
cells shrink and reduce their differentiated functions in response to normal and injurious
factors
Hypertrophy
increase in cell mass accompanied by an augmented functional capacity in response to
physiological and pathophysiological demands
Hyperplasia
increase in functional capacity related to an increase in cell number because of mitotic
division
Metaplasia
replacement of one differentiated cell type with another
Dysplasia
disorganized appearance of cells because of abnormal variations in size, shape, and
arrangement
What are the different types of necrosis?
coagulative, liquefactive, fat necrosis, and caseous necrosis
Coagulative necrosis
most common type; process begins with ischemia and ends with degradation of plasma
membrane
Liquifactive necrosis
dissolution of dead cells; formation of abscess or cyst from dissolved dead tissue
Fat necrosis
death of the adipose tissue that is the result of trauma or pancreatitis; chalky white area
of tissue
caseous necrosis