Etiology
study of the cause of disease
idiopathic
unknown cause
iatrogenic
caused by unintended or unwanted medical treatment
risk factor
increases likelihood of disease
Pathogenesis
development of disease
Clinical Manifestations
signs and symptoms
Stages and Clinical Course
-latent period
-prodromal period
-subclinical stage
-acute clinical course
-chronic clinical course
-exacerbation
-remission
-convalescence
-sequela
latent period
time between exposure of tissue to injurious agent and first appearance of signs and/or
symptoms
prodromal period
time during which first signs and/or symptoms appear/ onset of disease occurs
acute phase
disease/illness reaches its full intensity
, Acute clinical course
short-lived; may have severe manifestation
Chronic clinical course
may last months to years
exacerbation
increase in the severity of a disease or its symptoms
remission
decrease in severity, signs, or symptoms; may indicate disease is cured
convalescence
gradual recovery after an illness
Epidemiology
study of patterns of disease in populations
endemic disease
native to a local region
epidemic disease
spread to many people at the same time
pandemic disease
spread to large geographic areas
primary prevention
altering susceptibility or reducing exposure for susceptible persons
secondary prevention
early detection, screening, and management of disease
tertiary prevention
rehabilitation, supportive care, reducing disability, and restoring effective functioning
Homeostasis
state in which all symptoms are in balance
Homeostasis response
mechanistic, predictable series of orchestrated internal events
Allostasis
ability to successfully adapt to challenges
Stressors