BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION K
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ATZUNG TREVOR TEST BANK
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INCLUSIVEmOFmCHAPTERSm1-66 mCOMPLETEmWITHmEXPLAINEDmANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapterm1.mIntroduction:mThemNaturemof mDrugsm&mDrugmDevelopmentm&mRegulation
1.
Amnursemworkingmin mradiology madministersmiodine mto mampatientmwho mismhavi
ngmamcomputed mtomography m(CT)mscan.mThemnursemworkingmon mthemoncology
munitmadministers mchemotherapy mto mpatients mwho mhave mcancer. mAtmthe mPublic m
Health mDepartment,mamnursemadministersmammeasles-mumps-
rubellam(MMR)mvaccinemto mam14-month-
old mchild masmamroutinemimmunization. mWhich mbranch mofmpharmacology mbestmd
escribesmthemactionsmof mallmthreem nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology mismthemstudy mof mthembiologicmeffectsmofmchemicals.mNursesmarem
involved mwith mclinicalmpharmacology mormpharmacotherapeutics, mwhich mismamb
ranch mof mpharmacology mthatmdealsmwith mthemusesmof mdrugsmto mtreat,mprevent,m
and mdiagnose mdisease.mThemradiology mnursemismadministeringmamdrugmto mhelp m
diagnose mamdisease.mThemoncology mnursemismadministeringmamdrugmto mhelp mtrea
tmamdisease.mPharmacoeconomics mincludesmany mcostsminvolved min mdrugmtherap
y.
Pharmacodynamics minvolvesmhowmamdrugmaffectsmthembody mand mpharmacokine
ticsmismhowmthembody mactsmon mthembody.
2.
When minvolved min mphasemIIImdrugmevaluation mstudies,m
whatmresponsibilitiesmwould mthemnurse mhave?
A) Workingmwith manimalsmwho maremgiven mexperimentalm drugs
B) Choosingmappropriate mpatientsmto mbeminvolved min mthemdrugm study
C) Monitoringmand mobservingmpatientsmclosely mformadverse m effects
D) Conductingmresearch mto mdetermine meffectivenessmof mthem drug
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Ans: C
Feedback:
PhasemIIImstudiesminvolve musemof mamdrugmin mamvastmclinicalmpopulation min mwhic
h mpatientsmaremasked mto mrecord many msymptomsmtheymexperience mwhilemtakingm
themdrugs.mNursesmmay mbemresponsible mformhelpingmcollectmand manalyze mthemi
nformation mto mbemsharedmwith mthemFood mand mDrugmAdministration m(FDA)mbut
mwould mnotmconductmresearch mindependently mbecause mnurses mdo mnotmprescrib
emmedications.mUsemof manimalsmin mdrugmtestingmismdonemin mthempreclinicalmtria
ls.mSelectmpatientsmwho mareminvolved min mphasemIImstudiesmto mparticipate min mstu
diesmwhere mthemparticipantsmhavemthemdiseasemthemdrugmismintended mto mtreat.m
Thesempatientsmaremmonitored mclosely mformdrugmaction mand madverse meffects.mP
hasemImstudiesminvolve mhealthy mhuman mvolunteersmwho maremusually mpaid mformt
heirmparticipation.mNursesmmay mobserve mformadverse meffectsmand mtoxicity.
3.
Amphysician mhasmordered mintramuscularm(IM)minjectionsmof mmorphine,mamna
rcotic,mevery m4 mhoursmasmneeded mformpain min mammotormvehiclemaccidentmvictim
.mThemnurse mismaware mthismdrugmhasmamhigh mabusempotential.mUndermwhatmcate
gory mwould mmorphine mbemclassified?
A) Schedule mI
B) Schedule mII
C) Schedule mIII
D) Schedule mIV
Ans: B
Feedback:
Narcoticsmwith mamhigh mabusempotentialmaremclassified masmSchedule mIImdrugsm
because mof mseveremdependence mliability.mSchedule mImdrugsmhavemhigh mabuse
mpotentialmand mno maccepted mmedicalmuse. mSchedule mIIImdrugs mhave ma mlesserm
abusempotentialmthan mIImand man maccepted mmedicalmuse.mSchedule mIVmdrugsmha
vemlowmabusempotentialmand mlimited mdependence mliability.
4.
Whatmconceptmismconsidered mwhen mgenericmdrugsmaremsubstituted mformbr
and mnamemdrugs?
A) Bioavailability
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