Test Bank for Introductory
Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 06-10
C HAPTER 06: A NTIBACTERIAL D RUGS :
S ULFONAMIDES
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. A client, diagnosed with a urinary tract infection, indicates the use of an herbal
product to help prevent and relieve the symptoms. Which herb has the client
most likel y been using?
A) Ginger
B) Feverfew
C) Saw palmetto
D) Cranberry
Answer: D
Rationale: Cranberries and cranberry juice are commonl y used remedies for
preventing and relieving symptoms of UTIs. However, if an individual
suspects a UTI, medical attention is necessary.
Question Format: Multiple Choice
, Chapter: 6
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 72, Herbal Considerations
2. The nurse is preparing to administer sulfadiazi ne to a client who is also taking
warfarin. The nurse would be alert for which potential adverse effect?
A) Prolonged clotting times
B) Increased risk of infection
C) Decreased antibiotic effect
D) Decreased white blood cell count
Answer: A
Rationale: When war farin and sulfonamides are given concomitantl y, an
increase in action of the anticoagulant is seen, leading to an increase in
clotting time, such as PT/ INR, and an increased risk of bleeding. An
increased risk of infection and a decrease in the white blood cell count would
occur when a sulfonamide is given with methotrexate. The combination of
warfarin and sulfonamide does not impact the effect of the antibiotic.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 71, Interactions
3. A nurse is to administer sulfasalazine to a client with ulcerative colitis. Which
interventions would be most important while caring for this client?
A) Stop dosage if skin turns orange -yellow color.
B) Regularl y inspect client's stool samples.
, C) Give the drug on an empt y stomach.
D) Administer cranberry juice to the client.
Answer: B
Rationale: While providing care to a client receiving sulfasalazine therapy
for ulcerative colitis, the nurse should regularl y inspect all stool samples and
record their number and appearance. Yellow skin or urine in clients receiving
sulfasalazine is normal, and the nurse should not stop the dosage.
Sulfasalazine is administered with meals or immediatel y afterward, not on an
empt y stomach.
Administering cranberry juice is helpfu l for clients with urinary tract
infections, but not for clients with ulcerative colitis.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 72, Ongoing Assessment
4. An elderl y client receiving treatment for a urinary tract infection is now
reporting diarrhea. On assessment, the nurse notes the client has been recei ving
the appropriate medication as well as drinking cranberry juice. Which factor is
most likel y the cause of the client's condition?
A) Extremel y large dosage of cranberry juice
B) Lack of activit y or exercise
C) Occurrence of crystalluria
D) Minimized food and fluid intake
Answer: A
Rationale: Clients may develop gastrointestinal distress such as diarrhea if
they have consumed extremel y large doses of cranberry juice. The
recommended dose is 6 oz of juice twice dail y. Cranberry juice on an empt y
, stomach or immediatel y after dosage will not lead to diarrhea if taken in the
recommended amount.
Minimized food and fluid intake or lack of exercise does not increase the
chances of diarrhea. Crystalluria does not cause diarrhea.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 72, Herbal Considerations
5. A nurse is about to administer mafenide to a client. The nurse would be alert for
which possible reaction?
A) Rash, itching, or other allergic reactions
B) Crystals in the urine sample
C) Inflammation of the mouth
D) Loss of appetite
Answer: A
Rationale: The nurse should assess for allergic reactions such as rash,
itching, edema, and urticaria when administering mafenide. Topical
sulfonamides like mafenide do not cause crystalluria, inflammation of the
mouth, or loss of appetite.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 7
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 71, Other R eactions
Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 06-10
C HAPTER 06: A NTIBACTERIAL D RUGS :
S ULFONAMIDES
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. A client, diagnosed with a urinary tract infection, indicates the use of an herbal
product to help prevent and relieve the symptoms. Which herb has the client
most likel y been using?
A) Ginger
B) Feverfew
C) Saw palmetto
D) Cranberry
Answer: D
Rationale: Cranberries and cranberry juice are commonl y used remedies for
preventing and relieving symptoms of UTIs. However, if an individual
suspects a UTI, medical attention is necessary.
Question Format: Multiple Choice
, Chapter: 6
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 72, Herbal Considerations
2. The nurse is preparing to administer sulfadiazi ne to a client who is also taking
warfarin. The nurse would be alert for which potential adverse effect?
A) Prolonged clotting times
B) Increased risk of infection
C) Decreased antibiotic effect
D) Decreased white blood cell count
Answer: A
Rationale: When war farin and sulfonamides are given concomitantl y, an
increase in action of the anticoagulant is seen, leading to an increase in
clotting time, such as PT/ INR, and an increased risk of bleeding. An
increased risk of infection and a decrease in the white blood cell count would
occur when a sulfonamide is given with methotrexate. The combination of
warfarin and sulfonamide does not impact the effect of the antibiotic.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 71, Interactions
3. A nurse is to administer sulfasalazine to a client with ulcerative colitis. Which
interventions would be most important while caring for this client?
A) Stop dosage if skin turns orange -yellow color.
B) Regularl y inspect client's stool samples.
, C) Give the drug on an empt y stomach.
D) Administer cranberry juice to the client.
Answer: B
Rationale: While providing care to a client receiving sulfasalazine therapy
for ulcerative colitis, the nurse should regularl y inspect all stool samples and
record their number and appearance. Yellow skin or urine in clients receiving
sulfasalazine is normal, and the nurse should not stop the dosage.
Sulfasalazine is administered with meals or immediatel y afterward, not on an
empt y stomach.
Administering cranberry juice is helpfu l for clients with urinary tract
infections, but not for clients with ulcerative colitis.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 72, Ongoing Assessment
4. An elderl y client receiving treatment for a urinary tract infection is now
reporting diarrhea. On assessment, the nurse notes the client has been recei ving
the appropriate medication as well as drinking cranberry juice. Which factor is
most likel y the cause of the client's condition?
A) Extremel y large dosage of cranberry juice
B) Lack of activit y or exercise
C) Occurrence of crystalluria
D) Minimized food and fluid intake
Answer: A
Rationale: Clients may develop gastrointestinal distress such as diarrhea if
they have consumed extremel y large doses of cranberry juice. The
recommended dose is 6 oz of juice twice dail y. Cranberry juice on an empt y
, stomach or immediatel y after dosage will not lead to diarrhea if taken in the
recommended amount.
Minimized food and fluid intake or lack of exercise does not increase the
chances of diarrhea. Crystalluria does not cause diarrhea.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 72, Herbal Considerations
5. A nurse is about to administer mafenide to a client. The nurse would be alert for
which possible reaction?
A) Rash, itching, or other allergic reactions
B) Crystals in the urine sample
C) Inflammation of the mouth
D) Loss of appetite
Answer: A
Rationale: The nurse should assess for allergic reactions such as rash,
itching, edema, and urticaria when administering mafenide. Topical
sulfonamides like mafenide do not cause crystalluria, inflammation of the
mouth, or loss of appetite.
Question Format: Multiple Choice
Chapter: 6
Learning Objective: 7
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 71, Other R eactions
