Test Bank for Introductory
Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 21-25
C HAPTER 21: A NTIDEPRESSANT D RUGS
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. The nurse is assessing a client for depression. Which sym ptom would the nurse
prioritize?
A) Drowsiness
B) Extreme sadness
C) Severe headache
D) Dilated pupils
Answer: B
Rationale: The nurse should monitor the client for extreme sadness
becausethis is a symptom of depression. Drowsiness is an adverse effect of
most antidepressants. Severe headache and dilated pupils are symptoms of
hypertensive crisis which can occur when MAOIs are combined with
tyramine, tryptophan, and meperidine.
Question Format: Multiple Choice
Chapter: 21
, Learning Objective: 1
Cognitive Level: Appl y
Client Needs: Psychosocial Integrit y
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 251, Introduction
2. A client with depression has been prescribed amitript yline. Which drug action
should the nurse integra te into the teaching session for the client?
A) Decreased reuptake of norepinephrine
B) Increased serotonin in the nervous system
C) Increased endogenous norepinephrine
D) Increased endogenous epinephrine
Answer: A
Rationale: The nurse should identify decrease d reuptake of norepinephrine as
the effect of the tricyclic antidepressant on the client's body. Increased
serotonin in the nervous system, increased endogenous norepinephrine, and
increased endogenous epinephrine are effects of monoamine oxidase
inhibitors.
Question Format: Multiple Choice
Chapter: 21
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 255, T ricyclic Antidepressants
3. A nurse is caring for an older adult client who has been prescribed amoxapine
for depression accompanied by anxiet y. After administration of the drug, the
nurse observes muscle rigidit y and sweating. Which action should the nurse
prioritize?
A) Suggest the client engage in exercise.
B) Get the client to drink a glass of cold water.
C) Encourage the client to breathe deepl y.
, D) Stop the drug and contact the health care provider.
Answer: D
Rationale: The nurse should identify these as s ymptoms of neuroleptic
malignant syndrome and discontinue the drug administration and contact the
health care provider. Exercising, drinking cold water, and encouraging deep
breaths will not help the client with these symptoms.
Question Format: Multiple C hoice
Chapter: 21
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 255, Tricyclic Antidepressants
4. A nurse is preparing to teach a client and caregiver about the antidepressant
therapy which will be continued at home. Which precaution should the nurse
suggest if the client experiences dizziness when getting out of bed?
A) Strictl y avoid movements if dizziness occurs.
B) Rise slowl y when getting out of bed.
C) Have breakfast before getting out of bed.
D) Have a glass of water to overcome dizziness.
Answer: B
Rationale: The nurse should instruct the client to rise slowl y when getting
out of bed. Strictl y avoiding m ovements will restrict the client's mobilit y,
which is unadvisable. Having breakfast or a glass of water before getting out
of bed will not help the client to overcome dizziness because the dizziness is
not due to lack of nourishment.
Question Format: Mul tiple Choice
Chapter: 21
Learning Objective: 6
, Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Potential
Integrated Process: Teaching/Learning
Reference: p. 261, Educating the Client and Famil y
5. A nurse is caring for a client with suicidal tendencies. Which action would be
most important for the nurse to do after administering the drug orall y?
A) Inspect the oral cavity to ensure that the drug is swallowed.
B) Monitor body temperature for changes.
C) Monitor blood pressure f or unusual changes.
D) Inspect pulse rate for unusual changes.
Answer: A
Rationale: The immediate nursing intervention is to inspect the oral cavit y to
ensure that the client swallowed the drug. Assessment for changes in body
temperature, blood pressure, and pulse rate should be completed once the
nurse ensures that the client has swallowed the drug.
Question Format: Multiple Choice
Chapter: 21
Learning Objective: 6
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Poten tial
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 260, Suicide Attempt Risk
6. A nurse is caring for a client who has been prescribed a monoamine oxidase
inhibitor (MAOI). Which food should the nurse instruct the cl ient to avoid?
A) Milk
B) Butter
C) Rice
D) Yogurt
Answer: D
Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 21-25
C HAPTER 21: A NTIDEPRESSANT D RUGS
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. The nurse is assessing a client for depression. Which sym ptom would the nurse
prioritize?
A) Drowsiness
B) Extreme sadness
C) Severe headache
D) Dilated pupils
Answer: B
Rationale: The nurse should monitor the client for extreme sadness
becausethis is a symptom of depression. Drowsiness is an adverse effect of
most antidepressants. Severe headache and dilated pupils are symptoms of
hypertensive crisis which can occur when MAOIs are combined with
tyramine, tryptophan, and meperidine.
Question Format: Multiple Choice
Chapter: 21
, Learning Objective: 1
Cognitive Level: Appl y
Client Needs: Psychosocial Integrit y
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 251, Introduction
2. A client with depression has been prescribed amitript yline. Which drug action
should the nurse integra te into the teaching session for the client?
A) Decreased reuptake of norepinephrine
B) Increased serotonin in the nervous system
C) Increased endogenous norepinephrine
D) Increased endogenous epinephrine
Answer: A
Rationale: The nurse should identify decrease d reuptake of norepinephrine as
the effect of the tricyclic antidepressant on the client's body. Increased
serotonin in the nervous system, increased endogenous norepinephrine, and
increased endogenous epinephrine are effects of monoamine oxidase
inhibitors.
Question Format: Multiple Choice
Chapter: 21
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 255, T ricyclic Antidepressants
3. A nurse is caring for an older adult client who has been prescribed amoxapine
for depression accompanied by anxiet y. After administration of the drug, the
nurse observes muscle rigidit y and sweating. Which action should the nurse
prioritize?
A) Suggest the client engage in exercise.
B) Get the client to drink a glass of cold water.
C) Encourage the client to breathe deepl y.
, D) Stop the drug and contact the health care provider.
Answer: D
Rationale: The nurse should identify these as s ymptoms of neuroleptic
malignant syndrome and discontinue the drug administration and contact the
health care provider. Exercising, drinking cold water, and encouraging deep
breaths will not help the client with these symptoms.
Question Format: Multiple C hoice
Chapter: 21
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 255, Tricyclic Antidepressants
4. A nurse is preparing to teach a client and caregiver about the antidepressant
therapy which will be continued at home. Which precaution should the nurse
suggest if the client experiences dizziness when getting out of bed?
A) Strictl y avoid movements if dizziness occurs.
B) Rise slowl y when getting out of bed.
C) Have breakfast before getting out of bed.
D) Have a glass of water to overcome dizziness.
Answer: B
Rationale: The nurse should instruct the client to rise slowl y when getting
out of bed. Strictl y avoiding m ovements will restrict the client's mobilit y,
which is unadvisable. Having breakfast or a glass of water before getting out
of bed will not help the client to overcome dizziness because the dizziness is
not due to lack of nourishment.
Question Format: Mul tiple Choice
Chapter: 21
Learning Objective: 6
, Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Potential
Integrated Process: Teaching/Learning
Reference: p. 261, Educating the Client and Famil y
5. A nurse is caring for a client with suicidal tendencies. Which action would be
most important for the nurse to do after administering the drug orall y?
A) Inspect the oral cavity to ensure that the drug is swallowed.
B) Monitor body temperature for changes.
C) Monitor blood pressure f or unusual changes.
D) Inspect pulse rate for unusual changes.
Answer: A
Rationale: The immediate nursing intervention is to inspect the oral cavit y to
ensure that the client swallowed the drug. Assessment for changes in body
temperature, blood pressure, and pulse rate should be completed once the
nurse ensures that the client has swallowed the drug.
Question Format: Multiple Choice
Chapter: 21
Learning Objective: 6
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Poten tial
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 260, Suicide Attempt Risk
6. A nurse is caring for a client who has been prescribed a monoamine oxidase
inhibitor (MAOI). Which food should the nurse instruct the cl ient to avoid?
A) Milk
B) Butter
C) Rice
D) Yogurt
Answer: D
