Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 46-50
C HAPTER : 46: U RINARY T RACT A NTI -
I NFECTIVES AND O THER U RINARY D RUGS
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. The nursing instructor is teaching a session explaining the various drugs used to
treat urinary tract infections. The instructor determines the session is successful
when the students correctl y choose which organ as most often affected by
infections?
A) Bladder
B) Kidney
C) Urethra
D) Ureters
Answer: A
Rationale: The urinary tract consists of the following anatomic structures:
kidneys, ureters, bladder, prostate gland, and urethra. UTIs most commonl y
affect the bladder.
, Question format: Multiple Choice
Chapter: 46
Learning Objective: 1
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Physiological Adaptation
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 624, Figure 46.1 Routes of infection in the urinary tract
2. A client with a UTI is experiencing dysuria. The nurse would expect which drug
to be prescribed?
A) Nitrofurantoin
B) Oxybut ynin
C) Sulfamethoxazole/trimethoprim
D) Phenazopyridine
Answer: D
Rationale: Phenazopyridine is a urinary tract analgesic that is useful in
treating dysuria caused by a UTI. Sulfamethoxazole/trimethoprim is a
combination urinary anti -infective drug. Nitrofurantoin is an anti -infective
drug used for UTIs. Oxybut ynin is an antispasmodic drug used for overactive
bladder.
Question format: Multiple Choice
Chapter: 46
Learning Objective: one
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 624, Actions and Uses
3. A nurse caring for a client taking warfarin develops a UTI. The nurse should
monitor the client for increased risk of bleeding if which anti -infective is
prescribed?
A) Fosfom ycin
, B) Methenamine
C) Sulfamethoxazole
D) Nitrofurantoin
Answer: C
Rationale: Sulfamethoxazole, when administered concomitantly with
warfarin, can increase a client's risk for bleeding. This interaction is not
associated with fosfomycin, methenamine, or nitrofurantoin. Nitrofurantoin
should be used cautiousl y with magnesium trisilicate or magaldrate, and
anticholinergics due to potential adverse reactions. Methenamine should not
be used with antacids containing sodium bicarbonate or cosium carbonate due
to potential adverse reactions. Fosfom ycin should be used cautiousl y with
metoclopramide due to adverse reactions.
Question format: Multiple Choice
Chapter: 46
Learning Objective: 1
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Potential
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 625, Anti-Infectives
4. A nurse has administered amoxicillin to a client for a UTI. The nurse will
prioritize which assessment finding on the ongoing assessment?
A) Abdominal cramps
B) Vaginitis
C) Bladder irritation
D) Stomatitis
Answer: D
Rationale: The nurse should monitor for stomatitis in the client, which is an
adverse reaction to amoxicillin, an anti -infective drug. Vaginitis is an
adverse reaction to an anti - infective drug called fosfom ycin. Abdominal
cramps and bladder irritation are adverse reacti ons to the anti -infective drug
methenamine.
, Question format: Multiple Choice
Chapter: 46
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 628, Summary Drug Table
5. A nurse is preparing to administer methenamine to a client for UTI. The nurse
will question this order if the client is noted to be allergic to which substance?
A) Sulfa
B) Tartrazine
C) Shellfish
D) Penicillin
Answer: B
Rationale: Clients who are allergic to tartrazine, a food dye, should not
receive methenamine. Allergies to sulfa drugs, penicillins, or shellfish are
not noted to interact adversel y with methenamine.
Question format: Multiple Choice
Chapter: 46
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 625, Contraindications and Precautions
6. A nurse is teaching a client how to properly administer fosfomycin. The nurse
determines the session is successful when the client correctl y points out they
will administer the drug in which manner?
A) Administer the drug every 3 hours.
B) Dissolve the drug in 90–120 m L of hot water.
C) Ingest the drug immediatel y after mixing with water.