Clinical Pharmacology 12th
Edition by Susan M Ford
Chapter 41-45
C HAPTER 41: P ITUITARY AND
A DRENOCORTICAL H ORMONES
Ford: Introductory Clinical Pharmacology 12th Edition
Multiple Choice
1. The nurse has administered gonadotropin to a client. Which assessment finding
should the nurse prioritize?
A) Abdominal pain
B) Visual disturbances
C) Auditory disturbances
D) Ascites
Answer: B
Rationale: If the client reports visual disturbances, the drug therapy is
discontinued and the primary hea lth care provider notified. An examination
by an ophthalmologist is usuall y indicated. Abdominal pain and ascites are
adverse reactions that may or may not require discontinuation of the drug.
Auditory disturbances are not associated with this drug.
, Question Format: Multiple Choice
Chapter: 41
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Potential
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 553, Client R eceiving a Gonadotropin
2. The nurse is teaching a client about the ACTH which has been prescribed. The
nurse determines the session is successful when the client correctl y points out
they will need to avoid which medication?
A) Live vaccines
B) Thyroid hormones
C) NSAIDs
D) Cold preparations
Answer: A
Rationale: Clients taking ACTH should avoid any vaccination with live virus
as it may increase any adverse reaction to the vaccine, and decrease the
client's antibody response to the vaccine. Clients with hypothyr oidism should
use glucocorticoids cautiousl y. The use of NSAIDs and cold preparations are
not contraindicated with the use of ACTH; however, the nurse should
evaluate each client individuall y to ensure there are no other reasons to avoid
these medications.
Question Format: Multiple Choice
Chapter: 41
Learning Objective: 5
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Reduction of Risk Potential
Integrated Process: Teaching/Learning
Reference: p. 557, Uses
,3. A client with nocturnal enu resis is prescribed desmopressin acetate. Which
assessment finding should the nurse prioritize for this client?
A) Nasal congestion
B) Breast tenderness
C) Fluid retention
D) Gynecomastia
Answer: A
Rationale: The nurse should monitor for nasal congestion, abdo minal cramps,
headache, and nausea in the client as the adverse reactions to desmopressin
acetate. When the client is administered gonadotropin, the nurse needs to
monitor for fluid retention and gynecomastia as the adverse reactions to the
drug. When choriogonadotropin alfa is administered to the client, the nurse
should monitor for breast tenderness, ovarian overstimulation, and vasomotor
flushes as the adverse reactions to the drug.
Question Format: Multiple Choice
Chapter: 41
Learning Objective: 2
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 563, Summary Drug Table
4. A health care provider has prescribed vasopressin to th e client. Which
assessment should the nurse perform on the ongoing assessment?
A) Observe for and report any evidence of edema, such as dyspnea.
B) Measure and record the client's abdominal girth every hour.
C) Observe the client for blanching of the skin, abdom inal cramps, and
nausea.
D) Weigh the client every day to obtain a baseline weight.
Answer: C
Rationale: After vasopressin is administered to the client, the nurse should
observe the client every 10 to 15 minutes for signs of an excessive dosage,
, which include blanching of the skin, abdominal cramps, and nausea.
Aftercorticotropin is administered to the client, the nurse needs to observe
for and report any evidence of edema, such as weight gain, rales, increased
pulse or dyspnea, or swollen extremities. I f the client is receiving
vasopressin for abdominal distention, the nurse needs to auscultate the
abdomen every 15 to 30 minutes and measure abdominal girth hourl y. The
nurse needs to weigh the client to obtain a baseline weight for future
comparison befor e administering vasopressin to the client.
Question Format: Multiple Choice
Chapter: 41
Learning Objective: 3
Cognitive Level: Appl y
Client Needs: Physiological Integrit y: Pharmacological Therapies
Integrated Process: Clinical Problem -solving Process (Nursing Process)
Reference: p. 550, Client Receiving Vasopressin
5. A nurse is preparing to administer gonadotropin to a client. The nurse would
question this order if which disorder is documented in the client's medical
history?
A) Sensitivit y to benz yl a lcohol
B) Epiphyseal closure
C) Adrenal dysfunction
D) Epilepsy
Answer: C
Rationale: Gonadotropins are contraindicated in clients with adrenal
dysfunction, high gonadotropin levels, thyroid dysfunction, liver disease,
abnormal bleeding, ovarian cysts, sex -hormone-dependent tumors, or organic
intracranial lesions (pituitary tumors). Gonadotropins should be used
cautiousl y in clients with epilepsy. Somatropin growth hormones are
contraindicated in clients with sensitivit y to benz yl alcohol, epiphyseal
closure, and underl ying cranial lesions.
Question Format: Multiple Choice
Chapter: 41
Learning Objective: 2