BLD 430 EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS VERIFIED GRADED A++
Diploid is what?
Us
Haploid is what?
Gametes
Can have lots of variations with what chromosomes?
X and Y
An allele is a what?
Gene
A loci is what?
Where on the chromosome you can find the gene
The further two genes are apart, the more likely you will get what?
recombination
What is gene linkage?
The closer two genes are together on the chromosome, the more likely they are to be
inherited together and move as a block
What is linkage disequilibrium?
When you see a difference in gene frequency that you wouldn't expect normally due to
linkage
What is the magic number for a Iod score?
,3
If you increase your Iod score, you get a what in linkage?
increase
What are the hardy weinburg equilibrium assumptions about normal distribution?
There's no selection advantage, a large population, and random mating. Also the
disease can't affect fertility (the ability to live long enough to mate)
Eye color is what type of trait?
mutagenic
What is epistasis?
More than just the gene influences phenotype
How does the birth order go in a pedigree?
Oldest are to the left, youngest to the right
Purines have how many rings?
2
Pyrimidines have how many rings?
1
What is the central dogma?
DNA--transcription-->RNA---translation-->Proteins
Are exons or introns spliced out?
Introns are spliced out
What is the initiator for DNA?
ATG
What codon is to start and what amino acid is that?
, AUG, Met - the only start codon
What are the stop codons?
UAG, UAA, UGA
How is DNA read?
5' to 3'
How is anti-sense read?
3'-5'
How can DNA have secondary structure?
hairpin loops, tRNA
What are oligonucleotides?
A string of bases
What is the Tm equation?
2(AT)+4(GC)
What is a missense mutation?
point mutation that codes for a different amino acid
What is a framshift mutation?
An insertion or deletion that changes the reading frame
What is a nonsense mutation?
Point mutation that results in a stop codon
If you are doing genotyping in an assay, you need what?
DNA
If you are doing a gene expression assay, you need what?
RNA
COMPLETE SOLUTIONS VERIFIED GRADED A++
Diploid is what?
Us
Haploid is what?
Gametes
Can have lots of variations with what chromosomes?
X and Y
An allele is a what?
Gene
A loci is what?
Where on the chromosome you can find the gene
The further two genes are apart, the more likely you will get what?
recombination
What is gene linkage?
The closer two genes are together on the chromosome, the more likely they are to be
inherited together and move as a block
What is linkage disequilibrium?
When you see a difference in gene frequency that you wouldn't expect normally due to
linkage
What is the magic number for a Iod score?
,3
If you increase your Iod score, you get a what in linkage?
increase
What are the hardy weinburg equilibrium assumptions about normal distribution?
There's no selection advantage, a large population, and random mating. Also the
disease can't affect fertility (the ability to live long enough to mate)
Eye color is what type of trait?
mutagenic
What is epistasis?
More than just the gene influences phenotype
How does the birth order go in a pedigree?
Oldest are to the left, youngest to the right
Purines have how many rings?
2
Pyrimidines have how many rings?
1
What is the central dogma?
DNA--transcription-->RNA---translation-->Proteins
Are exons or introns spliced out?
Introns are spliced out
What is the initiator for DNA?
ATG
What codon is to start and what amino acid is that?
, AUG, Met - the only start codon
What are the stop codons?
UAG, UAA, UGA
How is DNA read?
5' to 3'
How is anti-sense read?
3'-5'
How can DNA have secondary structure?
hairpin loops, tRNA
What are oligonucleotides?
A string of bases
What is the Tm equation?
2(AT)+4(GC)
What is a missense mutation?
point mutation that codes for a different amino acid
What is a framshift mutation?
An insertion or deletion that changes the reading frame
What is a nonsense mutation?
Point mutation that results in a stop codon
If you are doing genotyping in an assay, you need what?
DNA
If you are doing a gene expression assay, you need what?
RNA
