COMPLETE SOLUTIONS VERIFIED GRADED A++
The steps of working through an unexpected antibody are:
Detection, Identification, Confirmation
The panel cells used to make a presumptive identification of an unexpected
antibody come from different donors who are what type
Group O
Panel cells used to make a presumptive ID of an unexpected antibody are antigen
typed for the more common antigens we encounter antibodies against and the
"+"'s and "0"'s we see on the antigen profile sheet reflect their antigen make up.
(true or false)
True
We review how our patient reacts with the cells in the panel and try to match our
pattern of reactivity with the reactivity pattern of the cells when they were typed
at the manufacturer, in other words, we look to see if our patient serum reactions
are negative where the antigen is lacking and positive where the antigen is
present. (True or false)
True
The panel cells that our patient does not react with can be used to "cross out"
antigens that are present on that cell and therefore thought not to be the
specificity of the antibody present. (True or false)
, True
The underlying assumption of "crossing out" is that since we know we have
given the antibody the opportunity to react with the antigens present on that cell,
we make the assumption if the cell is negative with our patient's serum, that the
specificity of the antibody in our patient is not on that cell. (True or false)
True
Once a presumptive identification is made, we must confirm by:
1. antigen typing the patient to confirm they are antigen negative and therefore
they could make that antibody.
2. run a select cell panel that is made up of 3 cells positive for the presumed
antigen and 3 cells negative, the patient pattern must match the antigen profile of
the six cells being positive when the antigen is present and negative when the
antigen is absent.
(True or False)
True
If the patient's antigen type reveals that they are positive for what you thought the
specificity of the unexpected antibody was, you would check the patient's cells in
an autocontrol to see if it was positive or negative. (true or false)
True
One assumes that a patient will not make an antibody against an antigen they
have. (True or false)
True