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Bipolar one disorder DSM five criteria - correct answer Manic episode: 1+ week of a colon
elevated, expansive or irritable mood and increase energy. 3+ symptoms from B: distractibility,
indiscretion, irresponsible, grandiosity, flight of ideas, activity(Increase goal-orient), decreased
need for sleep, talkativeness or pressured speech.
Bipolar two DSM five criteria - correct answer Hypo mania and major depressive disorder: hypo
mania same as mania with decreased severity and duration and no functional impairment for
episode of four or more days and no psychosis
Mixed episodes (bipolar) - correct answer Manic and depressive symptoms time by side usually
with comorbid substance abuse increased risk of suicide and psychosis
rapid cycling - correct answer Four or more cycles per year no greater than a week well period
Cyclothymia DSM-V Criteria - correct answer Two or more years of mood cycling with
dysthymia and hypo mania decreased intensity than bipolar disorder meets criteria for hypo
mania but does not meet criteria for major depressive disorder
Dysthymia DSM five criteria - correct answer HE'S 2 SAD depressive symptoms lasting two or
more years that is subsydromal characterized by hopelessness decreased energy, decrease self-
esteem for two years, abnormal sleep, abnormal appetite impaired decision-making.
MAOÍ Mechanism of action generally - correct answer Catalyzes the deamination of
monoamines intracellularly and MAO transport Reuptake extracellular monoamines
MAO-A Mechanism of action - correct answer MAO-A Oxidizes serotonin norepinephrine and
epinephrine
MAO-B Mechanism of action - correct answer Oxidizes phenylalanine
MAO-A and MAO-B mechanism of action - correct answer Oxidizes dopamine non-
preferentially
MAOs Neumonic -2 - correct answer Date with Tyra banks with wine and cheese in Maui— can
cause hypertensive crisis related to tyramine from aged food.
MAWIs= my arms weight increased= effective for atypical depression
MAOs adverse effects-6 - correct answer Hypertensive crisis, diet restriction, avoid meds, five
week after Prozac, two week after other antidepressants, no other medications for two weeks
after discontinuing
MAOs diet restriction-4 compounds - correct answer Tyrosine, high tyramine, tryptophan,
phenylalanine
, NURS 663 Exam 1 MOSTLY TESTED COMPLETE QUESTIONS WITH ANSWERS 100% VERIFIED 100%
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Tyrosine foods-10 - correct answer Aged cheese, aged wine, fava or broad bean pods,
sauerkraut, soy sauce, tap or draft beer, overripe fruit, cured meat, spoiled food
MAOs drugs to avoid- 6 - correct answer Antidepressants, Dextromethorphan, stimulants,
sympathomimetics, meperidine, disulfiram
MAOs side effects 11 - correct answer Increased weight, drowsy, dizzy, orthostatic
hypotension, tremor, headache, dry mouth, constipation, change in sexual drive, peripheral
Edema, sweating
Tricyclic mechanism of action - correct answer Inhibit 5HT2, norepinephrine, dopamine and
reuptake slows. Amino group interferes with ASP - 98 in HSERT. Causing down regulation of
receptors.
Tricyclic side effects - correct answer Anticholinergic effects (dry mouth, blurred vision,
constipation, urine retention, impotence). Histamine effects (sedation, increased weight).
Adrenergic alpha receptor (postural hypotension). Direct membrane effects (decrease seizure
threshold and arrhythmias). 5HT2 receptor (increase weight and decrease anxiety).
Amitriptyline dosing/Class - correct answer Start at 25 to 50 mg per day, titrate 25 to 50 mg per
day per week, Max dose is 300 mg per day/TCA
Names of tricyclics 10 - correct answer Amitriptyline, nortriptyline, clomipramine, imipramine,
protriptyline, doxepin, amoxapine, desipramine, mapratiline, tripramine
Tricyclics are useful-2 - correct answer Pain, migraine
Tricyclics adverse effects-2 - correct answer Overdoses are cardiotoxic, high potency increases
the risk of mania
Nortriptyline mnemonic - correct answer No-triptyline equals less sedation and hypotension
Tricyclics mnemonic-2 - correct answer Think car goes over tricycle to remember that an
overdose is cardiotoxic. Do you remember mechanism think trans =serotonin and
norepinephrine Chans= Na+ and Ca+ Ans= ACH and histamine
Clomipramine mnemonic/class - correct answer TCA- think comipramine for obsessive
compulsive disorder
Imipramine- pneumonic and class - correct answer I'm peeingamine- nocturnal enuresis
Unilateral electrode in ECT indications - correct answer Typically first line because it has less
cognitive side effects but has less efficacy
What is ECT? - correct answer The use of electrical shock current delivered to the brain to
induce a seizure that treats depression. Goal is to reverse atrophy.