NSG 552 PsychPharm Quiz 1 with verified answers
____ is a mild-mod CYP-450 inhibitor Ans✓✓✓ depakoe
--- has been shown to be more effective than placebo for MDD w/ atypical
features, MDD w/ psychotic features and social phobia. Ans✓✓✓ Phenelzine
2nd line treatment for depression Ans✓✓✓ TCAs-tricyclic antidepressants
3 C's of TCAs Ans✓✓✓ cadiotoxic, convulsions, coma
Activating Antidepress Ans✓✓✓ good for patients who want to avoid
medications that cause tiredness - e.g. Fluoxetine - Sertraline ---Escitalopram -
Effexor ( symptoms restlessness, agitation, anxiety)
acts on alpha adrenergic receptors Ans✓✓✓ trazadone
for MDD, anxiety, insombia
acute dystonia Ans✓✓✓ Sudden onset• Fixed/Sustained painful contraction of
the neck muscles(torticollis), tongue, eyes(oculogyric crisis)• Can be life
threatening if it affects airway
Agitation is a psychiatric emergency T/F Ans✓✓✓ True
Akasthesia Ans✓✓✓ Internal and external restlessness• Subjective anxiety,
restlessness, inability to remain still• Constant need to pace or walk
,Antidepressant tapering Ans✓✓✓ Gradual taper of medications
Least likely with Fluoxetine and Vortioxetine (Trintellix/Brintellix)- may consider
short trial to mitigate symptoms
Symptoms usually begin within 5 days of treatment cessation
Consider a 4-week taper (longer with Paxil and Effexor)
Antidepressant Withdrawal / Discontinuation Syndrome "FINISH" Ans✓✓✓ F= Flu
like symptoms (aches, pains, chills)
I= Insomnia
N= Nausea
I= Imbalance
S= Sensory disturbance (tremors, sensation of electrical shock)
H= Hyperarousal
Antipsychotics can take up to - weeks for response Ans✓✓✓ 6-8 weeks
Antipsychotics must occupy more than ---% of D2 receptors to cause EPS
Ans✓✓✓ 80%
baselines to monitor with Metabolic Syndrome Ans✓✓✓ Monitor Baseline and
ongoing(i.e. 3 months etc.)
• Weight
• Waist circumference
, • BP
• HbA1c
• Fasting lipids
NOTE: For patients established on antipsychotic medications, yearly labs should
be considered.
blackbox warning for SSRIs Ans✓✓✓ increased SI in children, adolescents, young
adults
Bupropion (Wellbutrin) 150-450mg Ans✓✓✓ Used in ADHD and smoking
cessation d/t effects on DA
Weight neutral
Bupropion (Wellbutrin) CI for Ans✓✓✓ seizures, eating d/o
Can cause priapism (prolonged erection) Ans✓✓✓ trazadone
Can increase LFTs
Used for depression, neuropathic pain and in fibromyalgia
Hepatotoxicity (monitor LFTs) Ans✓✓✓ SNRI - e.g. Duloxetine (Cymbalta)
caution using ______ meds in bipolar pts; may trigger rapid switch in
polarity/mania Ans✓✓✓ antidepressants
Characteristics of metabolic syndrome Ans✓✓✓ Abdominal obesity• Elevated
triglycerides• Low HDL levels• BP higher than 135/85 mm Hg
____ is a mild-mod CYP-450 inhibitor Ans✓✓✓ depakoe
--- has been shown to be more effective than placebo for MDD w/ atypical
features, MDD w/ psychotic features and social phobia. Ans✓✓✓ Phenelzine
2nd line treatment for depression Ans✓✓✓ TCAs-tricyclic antidepressants
3 C's of TCAs Ans✓✓✓ cadiotoxic, convulsions, coma
Activating Antidepress Ans✓✓✓ good for patients who want to avoid
medications that cause tiredness - e.g. Fluoxetine - Sertraline ---Escitalopram -
Effexor ( symptoms restlessness, agitation, anxiety)
acts on alpha adrenergic receptors Ans✓✓✓ trazadone
for MDD, anxiety, insombia
acute dystonia Ans✓✓✓ Sudden onset• Fixed/Sustained painful contraction of
the neck muscles(torticollis), tongue, eyes(oculogyric crisis)• Can be life
threatening if it affects airway
Agitation is a psychiatric emergency T/F Ans✓✓✓ True
Akasthesia Ans✓✓✓ Internal and external restlessness• Subjective anxiety,
restlessness, inability to remain still• Constant need to pace or walk
,Antidepressant tapering Ans✓✓✓ Gradual taper of medications
Least likely with Fluoxetine and Vortioxetine (Trintellix/Brintellix)- may consider
short trial to mitigate symptoms
Symptoms usually begin within 5 days of treatment cessation
Consider a 4-week taper (longer with Paxil and Effexor)
Antidepressant Withdrawal / Discontinuation Syndrome "FINISH" Ans✓✓✓ F= Flu
like symptoms (aches, pains, chills)
I= Insomnia
N= Nausea
I= Imbalance
S= Sensory disturbance (tremors, sensation of electrical shock)
H= Hyperarousal
Antipsychotics can take up to - weeks for response Ans✓✓✓ 6-8 weeks
Antipsychotics must occupy more than ---% of D2 receptors to cause EPS
Ans✓✓✓ 80%
baselines to monitor with Metabolic Syndrome Ans✓✓✓ Monitor Baseline and
ongoing(i.e. 3 months etc.)
• Weight
• Waist circumference
, • BP
• HbA1c
• Fasting lipids
NOTE: For patients established on antipsychotic medications, yearly labs should
be considered.
blackbox warning for SSRIs Ans✓✓✓ increased SI in children, adolescents, young
adults
Bupropion (Wellbutrin) 150-450mg Ans✓✓✓ Used in ADHD and smoking
cessation d/t effects on DA
Weight neutral
Bupropion (Wellbutrin) CI for Ans✓✓✓ seizures, eating d/o
Can cause priapism (prolonged erection) Ans✓✓✓ trazadone
Can increase LFTs
Used for depression, neuropathic pain and in fibromyalgia
Hepatotoxicity (monitor LFTs) Ans✓✓✓ SNRI - e.g. Duloxetine (Cymbalta)
caution using ______ meds in bipolar pts; may trigger rapid switch in
polarity/mania Ans✓✓✓ antidepressants
Characteristics of metabolic syndrome Ans✓✓✓ Abdominal obesity• Elevated
triglycerides• Low HDL levels• BP higher than 135/85 mm Hg
