Addison's disease is a deficency of what substances Ans✓✓✓ -cortistol and
mineralocorticoid from destruction of adrenal cortex
benefits of metformin Ans✓✓✓ -improves fasting and postprandial
hyperglycemia and hypertriglycemia in obese patients
-no wt gain
calculate lantus dose based on weight Ans✓✓✓ -young adult (<25):
0.35units/kg/day
-older adults= 0.35 units/kg/day
cushings with elevated ACTH causes Ans✓✓✓ -most caused by a benign ACTH
secreting pituitary adenoma
-small amount due to non-pit ACTH secreting neuroendocrine neoplasm
cushings with low ACTH levels causes Ans✓✓✓ -excessive secretion of cortisol by
adrenal glands
-most causes due to unilateral adrenal tumor
-ACTH dependent adrenal hyperplasia
describe labs in subclinical hypothyroidism Ans✓✓✓ -normal serum FT4 w/ a TSH
> reference range
DIAGNOSTIC criteria of DM Ans✓✓✓ -fasting BG > 126 on 2 occasions
- NON-FBG >200 and sx of DM
, -OGTT with a 2hr value of >200
-HgA1c > 6.5%
example of sick days for diabetics Ans✓✓✓ -feeling ill
-fever > 2 days with no improvement
-vomiting or diarrhea > 6hours
Grave's disease is characterized by Ans✓✓✓ increased synthesis and release of
thyroid hormones; autoantibodies (TSI) or TSH receptor antibodies bind to the
TSH receptor in thyroid membranes and stimulate the gland
HHS symptoms Ans✓✓✓ polydipsia/uria, wt loss, wkns
focal neuro def, seizures, aphasia, hallucinations
sx of extracellular fluid depletion (dehydration)
normothermia or hypothermia despite sx of infxn
How to calculate anion gap Ans✓✓✓ NA- (Cl + HCO3)
how to calculate corrected sodium Ans✓✓✓ measured NA +
1.6(glucose-100)/100
how to calculate serum osmolality Ans✓✓✓ 2(Na) + glucose/18
How to Diagnose DKA Ans✓✓✓ -Serum BGL > 250
-PH < 7.3