Pharmacology CNS Drugs EXAM 2025 EXAM
QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+
what is the core activity/function of the CNS? - Answer-neurotransmission
/.Name the two main neurotransmitters of the PNS - Answer-ACh and norepinephrine
/.norepinephrine is a neurotransmitter that is the major regulator of the
_________________ system, this system controls the body under stressful conditions -
Answer-sympathetic
/.Nearly all CNS drugs produce their effect by modifying certain _____________
_______ ______________ - Answer-steps in neurotransmission
/.ACh is the primary neurotransmitter in the ___________ system, which is the system
that controls the body function under normal conditions - Answer-parasympathetic
/.true or false, a single neuron can only synthesize 1 type of neurotransmitter - Answer-
true
/.action potential triggers the release of ? - Answer-neurotransmitters
/.neurotransmission can occur at action potential within the __________
______________ ___________ - Answer-same presynaptic neuron
/.true or false, neurotransmission can occur between the pre and post synaptic neuron -
Answer-true
/.major pathway for neurotransmitter release:
through synaptic vesicles being triggered by ? - Answer-action potential
/.what are the two reasons neurotransmitters are stored in synaptic vesicles - Answer-
protection and release
/.where do neurotransmitters get synthesized at? - Answer-inside neuron
/.Sodium and Calcium channels always ___________ in regards to their flow of ions -
Answer-influx
/.Potassium always ___________ in regard to their flow of ions - Answer-eflux
, /.in _________________, the neurons are not responsive to any stimulus and therefore
cannot fire - Answer-hyperpolarization
/.what is the major excitatory neurotransmitter in the CNS? - Answer-glutamate
/.about 50% of synapses in the CNS occur due to what neurotransmitter? - Answer-
glutamate
/.what is the major inhibitory neurotransmitter in the CNS? - Answer-GABA
/.about 1/3 of all synapses in the CNS are what neurotransmitter? - Answer-GABA
/.GABA works with Glutamate to maintain ? - Answer-homeostasis
/.glutamate synthesis
occurs in glutamatergic nerve terminals, ____________________ is converted into
glutamate by ____________ - Answer-a-ketoglutarate, GABA-T
/.Glutamate is stored in synaptic vessicles via _____________/H+-ATPase - Answer-
VGLUT
/.what is the specific marker for glutamate neurons? - Answer-VGLUT
/.Glutamate storage
H+-ATPase pumps H+ into the vesicle generating a _________ ___________, then
VGLUT uses this as an ____________ ___________ to transport glutamate molecules
into vesicles - Answer-proton gradient, energy source
/.VGLUT is a ______________ (antiporter/symporter) - Answer-antiporter
/.Glutamate release
in response to an action potential (depolarization), ____________ channels influx and
______________ occurs - Answer-calcium, exocytosis
/.Glutamate Deactivation
Reuptake into ______________ ___________ _________ or uptake into ___________
_________ - Answer-presynaptic nerve terminals, glial cells
/.Glutamate Deactivation
QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) |ALREADY GRADED A+
what is the core activity/function of the CNS? - Answer-neurotransmission
/.Name the two main neurotransmitters of the PNS - Answer-ACh and norepinephrine
/.norepinephrine is a neurotransmitter that is the major regulator of the
_________________ system, this system controls the body under stressful conditions -
Answer-sympathetic
/.Nearly all CNS drugs produce their effect by modifying certain _____________
_______ ______________ - Answer-steps in neurotransmission
/.ACh is the primary neurotransmitter in the ___________ system, which is the system
that controls the body function under normal conditions - Answer-parasympathetic
/.true or false, a single neuron can only synthesize 1 type of neurotransmitter - Answer-
true
/.action potential triggers the release of ? - Answer-neurotransmitters
/.neurotransmission can occur at action potential within the __________
______________ ___________ - Answer-same presynaptic neuron
/.true or false, neurotransmission can occur between the pre and post synaptic neuron -
Answer-true
/.major pathway for neurotransmitter release:
through synaptic vesicles being triggered by ? - Answer-action potential
/.what are the two reasons neurotransmitters are stored in synaptic vesicles - Answer-
protection and release
/.where do neurotransmitters get synthesized at? - Answer-inside neuron
/.Sodium and Calcium channels always ___________ in regards to their flow of ions -
Answer-influx
/.Potassium always ___________ in regard to their flow of ions - Answer-eflux
, /.in _________________, the neurons are not responsive to any stimulus and therefore
cannot fire - Answer-hyperpolarization
/.what is the major excitatory neurotransmitter in the CNS? - Answer-glutamate
/.about 50% of synapses in the CNS occur due to what neurotransmitter? - Answer-
glutamate
/.what is the major inhibitory neurotransmitter in the CNS? - Answer-GABA
/.about 1/3 of all synapses in the CNS are what neurotransmitter? - Answer-GABA
/.GABA works with Glutamate to maintain ? - Answer-homeostasis
/.glutamate synthesis
occurs in glutamatergic nerve terminals, ____________________ is converted into
glutamate by ____________ - Answer-a-ketoglutarate, GABA-T
/.Glutamate is stored in synaptic vessicles via _____________/H+-ATPase - Answer-
VGLUT
/.what is the specific marker for glutamate neurons? - Answer-VGLUT
/.Glutamate storage
H+-ATPase pumps H+ into the vesicle generating a _________ ___________, then
VGLUT uses this as an ____________ ___________ to transport glutamate molecules
into vesicles - Answer-proton gradient, energy source
/.VGLUT is a ______________ (antiporter/symporter) - Answer-antiporter
/.Glutamate release
in response to an action potential (depolarization), ____________ channels influx and
______________ occurs - Answer-calcium, exocytosis
/.Glutamate Deactivation
Reuptake into ______________ ___________ _________ or uptake into ___________
_________ - Answer-presynaptic nerve terminals, glial cells
/.Glutamate Deactivation
