Answers
_______rreductionrpotentialrmeansrthermoleculerhasrarhigherraffinityrforrelectrons,rthisrisrarg
oodr_____ragent.r-rCORRECTrrANSWER-Higher,roxidizing.
________randr_______rarerneededrtorreverserpyruvaterkinase.r-rCORRECTrrANSWER-
Pyruvatercarboxylase,rPEPrcarboxykinaser(PEPCK).
________risrresponsiblerforrproducingrglucoserwhenrbloodrglucoserisr____.r-
rCORRECTrrANSWER-Gluconeogenesis,rlow.
_____________risrusedrtorreverserPFKrinrthercytoplasm.r-rCORRECTrrANSWER-
Fructoser1,6rbisphosphatase.
(T/F)rMostrenzymesrinrgluconeogenesisrareralsorglycolysisrenzymes.r-
rCORRECTrrANSWER-True.
Armoleculesraffinityrforrelectronsrisrdescribedrbyritsr_____r_______r______.r-
rCORRECTrrANSWER-Standardrreductionrpotential.
Arredoxrreactionrinrwhichrelectronsrfromrther_____ragentrisrtransferredrtorther______ragent.r
-rCORRECTrrANSWER-Reducing,roxidizing.
AlthoughranimalsrcannotrgeneraterglucoserfromracetylrCoA,rplantsrandrmicro-
organismsrcanrproducerglucoserusingracetyl-CoArthroughrther______rcycle.r-
rCORRECTrrANSWER-glyoxylate
Anapleuroticrreaction:r-rCORRECTrrANSWER-
"Replenishrreactions".r(Conversionrofrpyruvatertoroxaloacetaterisrarmajorranapleuroticrreac
tion)
ATPrsynthaserisrregulatedrentirelyrbyrtheravailabilityrofr_______.r-rCORRECTrrANSWER-
ADP.r(Acceptorrcontrol).
ATPaserisrembeddedrinrtherinnerrmitochondrialrmembranerandrcontainsrtworparts:r-
rCORRECTrrANSWER-F0randrF1.
, AccessoryrproteinsrconnectrF0randrF1rinrsuchrarwayrsorthatrwhenrtherc-
ringrrotates,ralpha/betarsubunitsrdornot.
CACrisrcontrolledrbyrenergyrcharge:r-rCORRECTrrANSWER-
bothrenzymesr(Isocitraterdehydrogenaser&ralpha-
ketoglutaraterdehydrogenase)rarerinhibitedrbyrATPrandrNADHrwhilerADPrcanralsoractivateri
socitraterdehydrogenase.
ComplexrI:r-rCORRECTrrANSWER-
ElectronsrfromrNADHrarerusedrtorreducerubiquinoner(Q)rtorubiquinolr(QH2).rInrtherprocess,r
protonsrarerdirectlyrtransferredrfromrmatrixrintortherintermembranerspace.rItralsorconributesr
tortherprotonrgradientrbyrremovingrprotonsrfromrthermatrixrduringrtherreductionrofrubiquinon
e.
ComplexrII:r-rCORRECTrrANSWER-
TransfersrelectronsrfromrFADH2rtorubiquinone.rDoesrnotrcontributertortherestablishmentrofrt
herprotonrgradient.
ComplexrIII:r-rCORRECTrrANSWER-
transfersrelectronsrfromrubiquinolr(QH2)rtorcytochromerC.rTherQrcyclerofrcomplexrIIIrisrcentr
alrtoritsrfunction.rThertworQrbindingrsitesrofrcomplexrIIIrmakesrtherQrcyclerpossiblerandrallow
srcomplexrIIIrtortransferrelectronsrfromrQH2,rwhichrmustrtransferrbothrelectronsrsimultaneou
sly,rtorcytochromerC,rwhichrcanronlyracceptronerelectron.rTormakerthisrpossible,rcomplexrIIIr
bindsrQH2rinrsiterQ0randrQrinrsiterQi.rComplexrIIIrthenrpassesronerofrtherelectronsrfromrQH2r
tortheroxidizedrQrmoleculerinrsiterQi,rcreatingrarsemi-
quinone,randrtherotherronertorcytochromerC.rThersemi-
quinonerisrconvertedrtorQH2rwhenranotherrmoleculerofrQH2rbindsrtorQ0randrgivesritsrelectr
onsrtoranotherrmoleculerofrcytochromerCrandrthersemiquinone.rComplexrIIIrcontributesrtorth
erprotonrgradientrbecauseroxidizedrQH2rreleaseritsrprotonsrintortherintermembranerspacer
whilerreducedrQrtakerupritsrprotonsrfromrthermatrix.rNordirectrtransferrofrprotonsracrossrther
membranerisrcarriedrout.
ComplexrIV:r-rCORRECTrrANSWER-
transfersrcytochromerCrelectronsrtorO2,rproducingrwater.rInrtherprocess,rprotonsrarerdirectl
yrtransferredrintortherintermembranerspace.rProtonsrareralsorremovedrfromrthermatrixrtorfor
mrwater,rfurtherrincreasingrtherprotonrgradientracrossrtherinnerrmembrane.
Conversionrofrpyruvatertoracetyl-
CoArtakesrplacerinr______,rprecedesrther_____r______r_____,randronlyrtakesrplacerinrther
presencerofr_____.r-rCORRECTrrANSWER-Mitochondria,rcitricracidrcycle,rO2.
Covalentrmodification:r-rCORRECTrrANSWER-
PDHrkinaserphosphorylatesrtherenzymertordeactivaterE1.rPDHrphosphataserremovesrtherp
hosphate,rthusrreactivatingrit.