March 25
Nrsg265 Exam Complete Questions and Correct Detailed
Answers (Verified Answers)
Biguanides
Ans: Increases insulin sensitivity by increasing peripheral glucose uptake
Sulphonylureas
Ans: Increases insulin secretion
Pancreatic alpha cells produce
Ans: Glucagon when bgl is low
Pancreatic beta cells release
Ans: Insulin when bgl is high
Stored glucose (liver/muscle)
Ans: Glycogen
Insulin does what?
pg. 1
, March 25
Ans: Binds to insulin dependent cells so glut4 can open the cell and let in glucose
Triggers storage of excess glucose in the liver, as glycogen
Stimulates protein production & synthesis
Stimulates glucose to be stored as triglycerides
Normal fasting BGL
Ans: 4-6mmol
Insulin independent cells
Ans: Brain, rbcs,kidney,lens of the eye
What is Diabetes Mellitus?
Ans: Hyperglycaemia due to issues with insulin secretion, action or both
Type 1?
Ans: Beta cell destruction, severe or absolute insulin deficiency, caused by
autoimmune, genetics, environmental factors, viral infection
Type 2 Diabetes?
Ans: Insulin resistance and insulin deficiency - lifestyle causes, genetics/family hx,
obesity, sedentary
pg. 2
, March 25
Signs and symptoms of T1DM (early)
Ans: Polyphagia (hunger)
Polydipsia (thirst)
Polyuria (due to osmotic pull, too much urination)
Weight loss
Confusion
Fatigue
Late s&s T1DM
Ans: N+V
Abdo pain
Blurred vision
Tachycardia
Tachypnoea
Ketonic breath
Metabolic acidosis
Seizure
Coma
Treatment options for T1DM
Ans: Insulin is the only option
Mechanism of action Insulin
pg. 3
Nrsg265 Exam Complete Questions and Correct Detailed
Answers (Verified Answers)
Biguanides
Ans: Increases insulin sensitivity by increasing peripheral glucose uptake
Sulphonylureas
Ans: Increases insulin secretion
Pancreatic alpha cells produce
Ans: Glucagon when bgl is low
Pancreatic beta cells release
Ans: Insulin when bgl is high
Stored glucose (liver/muscle)
Ans: Glycogen
Insulin does what?
pg. 1
, March 25
Ans: Binds to insulin dependent cells so glut4 can open the cell and let in glucose
Triggers storage of excess glucose in the liver, as glycogen
Stimulates protein production & synthesis
Stimulates glucose to be stored as triglycerides
Normal fasting BGL
Ans: 4-6mmol
Insulin independent cells
Ans: Brain, rbcs,kidney,lens of the eye
What is Diabetes Mellitus?
Ans: Hyperglycaemia due to issues with insulin secretion, action or both
Type 1?
Ans: Beta cell destruction, severe or absolute insulin deficiency, caused by
autoimmune, genetics, environmental factors, viral infection
Type 2 Diabetes?
Ans: Insulin resistance and insulin deficiency - lifestyle causes, genetics/family hx,
obesity, sedentary
pg. 2
, March 25
Signs and symptoms of T1DM (early)
Ans: Polyphagia (hunger)
Polydipsia (thirst)
Polyuria (due to osmotic pull, too much urination)
Weight loss
Confusion
Fatigue
Late s&s T1DM
Ans: N+V
Abdo pain
Blurred vision
Tachycardia
Tachypnoea
Ketonic breath
Metabolic acidosis
Seizure
Coma
Treatment options for T1DM
Ans: Insulin is the only option
Mechanism of action Insulin
pg. 3
