The University of Nottingham
SCHOOL OF PHARMACY
A LEVEL 2 MODULE, SPRING SEMESTER 2021-2022
Asthma, Allergy and Immune Diseases
Mock exam
Answer BOTH questions
Answer each question fully; the marks for each section are clearly indicated. Marks will
also be awarded for written expression and ability to convey key points clearly.
Question 1
A novel β-adrenoceptor antagonist (Compound Y) was tested in segments of
airways from lungs, which have previously been shown to only contain the β2-
adrenoceptor subtype. Increasing concentrations of the β-adrenoceptor
agonist isoprenaline were added to the tissues in a cumulative manner.
Relaxation responses to isoprenaline were recorded in the absence or presence
-9
of the novel β-adrenoceptor antagonist Compound Y (1x10 M). Data are
expressed as percentage relaxation. (Figure 1).
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