Answers - Latest Edition.
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Prepare for success on the National Board of Medical Examiners (NBME)
Comprehensive Basic Science Examination (CBSE) with our comprehensive
resource: "NBME CBSE Real Exam 400 Questions and Answers - Latest
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concepts essential for your medical education.
Each question is crafted to reflect the structure and complexity of actual CBSE
exam questions, ensuring that you are well-prepared for the challenges you will
face. The latest edition incorporates recent updates in medical guidelines and
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,1. A 70-year-old male dies in a motor vehicle collision and was undergoing evaluation
for occult blood in the stool. What is the likely diagnosis based on a photo of the
transverse colon?
Answer: Tubular adenoma.
2. A 38-year-old male presents with a 1-week history of watery, itchy eyes and a runny
nose. Physical examination reveals inflamed nasal mucosa with no congestion in the
lower lung. What is the appropriate pharmacotherapy?
Answer: Loratadine.
3. A 42-year-old female has a 3-year history of an intermittent facial rash including the
forehead, eyelids, nose, and cheeks. The rash worsens since moving from New York
to Florida and is exacerbated by spicy foods. What is the diagnosis based on physical
examination?
Answer: Rosacea.
4. A 66-year-old male with stage IV colon cancer presents with a 3-day history of severe
diarrhea after receiving chemotherapy. What opioid antidiarrheal agent can be
prescribed that has no CNS effects?
Answer: Loperamide.
5. A 59-year-old female presents with a gradual onset of lack of muscle control in her
left arm and leg. Neurological examination shows ataxia of the left extremities. In
, which location is the metastatic tumor likely found?
Answer: Cerebellum.
6. A newborn delivered at 38 weeks weighs 1800 g and shows petechial rash,
microcephaly, and hepatosplenomegaly. Serologic testing indicates IgG positive in
both the mother and newborn, with IgM negative in the mother and positive in the
newborn. What does this indicate?
Answer: Congenital cytomegalovirus infection.
7. A 64-year-old male presents to the emergency department with shortness of breath
and extreme fatigue. The ECG shows atrial fibrillation, and he has ischemic heart
disease. What medication is likely administered intravenously?
Answer: Ibutilide.
8. A 65-year-old female with a 20-year history of osteoarthritis now has pain radiating
down her thigh, knee, and medial leg. What intervertebral foramina is likely affected
due to bony outgrowth compressing the spinal nerve?
Answer: L3 to L4.
9. A 38-year-old male with type 2 diabetes has an HbA1c of 10%. He is advised to start
insulin injections but expresses concern due to family history. What stage of change is
he in?
Answer: Contemplation.
, 10. A 24-year-old male with a 2-day history of an itchy rash shows edematous,
erythematous areas with linear vesicles. What cell types are activated in this response?
Answer: T lymphocytes.
11. A study evaluates the association between exposure to aniline dyes and bladder
cancer. If the odds ratio is calculated from the data provided in the study, what would
it be?
Answer: 3.
12. A 24-year-old male who uses intravenous drugs is unresponsive after injecting
himself with a substance 6 hours prior. Assuming first-order kinetics, what quantity of
drug did he inject if the half-life is 2 hours and volume of distribution is 200 L?
Answer: 480 mg.
13. A newborn has male genital ducts but female external genitalia. What type of study is
indicated based on the scenario?
Answer: Randomized clinical trial.
14. A 12-year-old boy immerses himself in 60°F water for 20 minutes. What
physiological changes occur in response to this?
Answer: Central blood volume increased, ADH decreased, Atrial Natriuretic Peptide
increased.