2025/2026
Somatic mutation - Correct Answer Extends only the life of the organism affected and all
daughter cells of that mutant cell. Only autosomal (body cells) are affected -> mitosis.
Germ line mutations - Correct Answer A heritable mutation, affects gametes
Indeles - Correct Answer Leads to frameshift mutations (collectively insertions and deletions)
Transition mutations - Correct Answer purine to purine or pyrimidine to pyrimidine. There are
4 possibilities
Transvertion mutation - Correct Answer a purine to pyrimidine mutation or vice versa. There
are 8 possibilities
Anticipation and fragile X - Correct Answer hair pin loop allows more and more repeats to be
made (fragile x is an example of anticipation)
Forward mutation - Correct Answer a change from WT to mutant
reversion mutation - Correct Answer change from mutants to WT (there are two kinds)
Partial reversion - Correct Answer restores protein function, but not exact WT sequence
Complete reversion - Correct Answer Restores WT protein coding sequence
Suppressor mutations - Correct Answer suppresses effect of an earlier mutation (two kinds)