Tietz Fundamentals Of
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CLINICAL CHEMISTRY AND
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MOLECULAR DIAGNOSTICS g
7th Edition By Carl A. Burtis
g g g g g
TEST BANK g
,TietzgFundamentalsgofgClinicalgChemistrygandgMoleculargDiagnosticsg7thg EditiongTestgBank
Tablegofgcontents:
I.gPrinciplesgOfgLaboratorygMedicine
Chapterg1.gClinicalgChemistry,gMoleculargDiagnostics,gandgLaboratorygMedicine
Chapterg2.gSelectiongandgAnalyticalgEvaluationgofgMethodsg—gWithgStatisticalgTechniques
Chapterg3.gClinicalgEvaluationgofgMethods
Chapterg4.gEvidence-BasedgLaboratorygMedicine
Chapterg5.gEstablishmentgandgUsegofgReferencegValues
Chapterg6.gSpecimengCollection,gProcessing,gandgOthergPreanalyticalgVariables
Chapterg7.gQualitygManagement
II.gAnalyticalgTechniquesgAndgInstrumentation
Chapterg8.gPrinciplesgofgBasicgTechniquesgandgLaboratorygSafety
Chapterg9.gOpticalgTechniques
Chapterg10.gElectrochemistrygandgChemicalgSensors
Chapterg11.gElectrophoresis
Chapterg12.gChromatography
Chapterg13.gMassgSpectrometry
Chapterg14.gEnzymegandgRategAnalyses
Chapterg15.gImmunochemicalgTechniques
Chapterg16gAutomation
Chapterg17.gPoint-of-CaregInstrumentation
III.g Analytes
Chapterg18.gAminogAcids,gPeptides,gandgProteins
Chapterg19.gSerumgEnzymes
Chapterg20.gTumorgMarkersgandgCancergGenes
Chapterg21.gKidneygFunctiongTestsg—gCreatinine,gGFR,gUrea,gandgUricgAcid
Chapterg22.gCarbohydrates
Chapterg23.gLipids,gLipoproteins,gApolipoproteins,gandgOthergCardiacgRiskgFactors
Chapterg24.gElectrolytesgandgBloodgGases
Chapterg25.gHormones
Chapterg26.g CatecholaminesgandgSerotonin
Chapterg27.g Vitamins,gTracegElements,gNutritionalgAssessment
Chapterg28.gHemoglobin,gIron,gandgBilirubin
Chapterg29.gPorphyrinsgandgPorphyrias
Chapterg30.gTherapeuticgDrugsgandgTheirgManagement
Chapterg31.gClinicalgToxicology
Chapterg32.g ToxicgMetals
IV.g Pathophysiology
Chapterg33.gDiabetes
,Chapterg34.g CardiovasculargDisease
Chapterg35.gKidneygDisease
Chapterg36.g PhysiologygandgDisordersgofgWater,gElectrolyte,gandgAcid-BasegMetabolism
Chapterg37.g LivergDisease
Chapterg38.g GastrointestinalgandgPancreaticgDiseases
Chapterg39.g DisordersgofgBonegandgMineralgMetabolism
Chapterg40.g DisordersgofgthegPituitarygGland
Chapterg41.g DisordersgofgthegAdrenalgCortex
Chapterg42.g ThyroidgDisorders
Chapterg43.g Reproduction-RelatedgDisorders
Chapterg44.g PregnancygandgPrenatalgTesting
Chapterg45.g NewborngScreeninggandg InborngErrorsgofgMetabolism
Chapterg46.gPharmacogenetics
V.g MoleculargDiagnostics
Chapterg47.gPrinciplesgofgMoleculargBiology
Chapterg48.gNucleicgAcidgTechniquesgandgApplications
Chapterg49.gGenomesgandgNucleicgAcidgAlterations
, TietzgFundamentalsgofgClinicalgChemistrygandgMolecularDiagnostics,g7egBurtisgTestgBank
Chapterg01:gClinicalgChemistry,gMoleculargDiagnostics,gandgLaboratorygMedicineTestgBa
nk
MULTIPLEgCHOICE
1. Angindividualgworkinggingagclinicalgchemistryglaboratorygisgmarriedgtogagsalesgrepresentative
gwhogworksgforgagcompanygthatgsellsgchemistryglaboratorygsupplies.gWhengtheglaboratorygm
anagergrequestsgaglistgofgneededgsupplies,gcostgofgsupplies,gandgvendors,gthisgindividualgonlyg
recommendsgthegspouse’sgcompanygasgthegvendor.gThisgisgconsideredgtogbega(n):
a. accountinggissue.
b. possiblegconflictgofginterest.
c. maintenancegofgconfidentialitygissue.
d. problemgwithgresourcegallocation.
ANS:g B
Concernghasgbeengraisedgovergtheginterrelationshipsgbetweengpractitionersgingthegmedicalgfieldg
andgcommercialgsuppliersgofgdrugs,gdevices,gequipment,getc.,gtogthegmedicalgprofession.
Similarly,grelationshipsghavegbeengscrutinizedgbetweengclinicalglaboratoriansgandgmanufacture
rsgandgprovidersgofgdiagnosticgequipmentgandgsupplies.gThesegconcernsgledgthegNationalgInstit
utesgofgHealthg(NIH)ging1995gtogrequiregofficialginstitutionalgreviewgofgfinancialgdisclosuregby
gresearchersgandgmanagementgofgsituationsgingwhichgdisclosuregindicatesgpotentialgconflictsgof
ginterest.
DIF: 1 REF:g Pageg4-5 OBJ:g 6g|g7
2. Agpatientgvisitsghergphysiciangstatinggthatghergprescribedgpainkillergisgnotgworkinggtogreduc
egthegpaingfollowingghergrecentgsurgery.gAgfriendgofgthegpatientgclaimsgthatgthegsamegpainki
llerg“workedgwonders”gtogreduceghergpaingaftergthegsamegsurgery.gThegphysiciangstatesgtha
tgthegdifferencegingthegeffectgofgthegdruggmightgbegcausedgby
,gwhichgisgstudiedgingpharmacog
enetics.
a. epidemiology
b. anginheritedgdisease
c. agconflictgofginterest
d. aggeneticgvariationgingdrug-metabolizinggenzymes
ANS:g D
Pharmacogeneticsgisgthegstudygofgtheggeneticgvariationgofgdruggmetabolismgbetweengindivi
duals.
DIF: 1 REF:g g Pageg3 OBJ:g 1
3. Johngworksgingagmoleculargdiagnosticsglaboratorygandgreceivesgagbloodgsamplegthatghasgth
egnamegofgagclosegfriendgprintedgongthegbar-
codedglabel.gTheggeneticgtestgthatgisgorderedgongthegfriend’sgsamplegwouldgprovidegdiagnos
ticginformationgaboutgagdisordergthatghasgagpoorgprognosis,gandgthegtestgisgusuallygperforme
dgbygJohn.gHegasksgagfellowgemployeegtoganalyzegthegsamplegforghimgandgnotgdivulgegthegr
esults.gThisgethicalgissuegconcerns:
a. confidentialitygofgpatientggeneticgandgmedicalginformation.
b. agconflictgofginterest.
c. resourcegallocation.
d. diagnosticgaccuracy.