PHAR 100 Final Exam 2024

PHAR 100 Final Exam 2024 Path of drug from when it enters to exits the body - Answer -1. Absorption 2. Distribution 3. Metabolism 4. Excretion Absorption - Answer -the movement of the drug from the site of administration into the bloodstream Distribution - Answer -the movement of a drug from the blood to the site of action and other tissues Metabolism - Answer -the conversion of a drug to a different chemical compound. Excretion - Answer -moving of the drug and its metabolites out of the body Routes of drug administration - Answer -1. Topical - On the skin -Transdermal -Inhalation 2. Enteral -Oral -Suppository -Buccal 3.Parenteral -IV -IM -SubcutaneousWhy and how do adverse drug reactions occur? - Answer -Example: a receptor is activated in a blood vessel by a drug designed to treat hypertension. The rector is activated by the ligand that is bound to it, and the blood pressure is lowered. However, this receptor may located in other areas of the body. The subsequent activation of this receptor in other areas of the body is an example of an adverse effect. Adverse effects - Answer -1. Extension of therapeutic effect 2. Unrelated to main drug action 3. Allergic reaction 4. Dependence and addiction 5. Teratogenesis