Test Bank For Basic & Applied Concepts of Blood Banking and Transfusion Practices 5th Edition by Paula R. Howard ISBN NO10,0323697399 ISBN NO 13,978-0323697392 All Chapters A+, Guide.

,DOWNLOADgTHEgTestgBankgforgBasicgandgAppliedgConceptsgofgBloodgBankinggandgT
ransfusiongPracticesg4thgEditiongHoward
Chapterg02:gImmunology:gBasicgPrinciplesgandgApplicationsgingthegBloodgBankgHowar
d:gBasicg&gAppliedgConceptsgofgBloodgBankinggandgTransfusiongPractices,g4thgEdition


MULTIPLEgCHOICE

1. Selectgthegcellginvolvedginghumoralgimmunity.
a. Neutrophils
b. Tglymphocytes
c. Bglymphocytes
d. Monocytes
ANS:g C
Bglymphocytesghavegthegabilitygtogtransformgintogplasmagcellsgtogproducegantibodies,gwhichgi
sgconsideredgaghumoralgresponse.

DIF: Levelg2 REF:g g p.g23

2. Whatgprocessgisgdescribedgbygopsonization?
a. Lysisgofgcells
b. Bindinggtogcellsgorgantigens
c. Ingestiongofgcells
d. Phagocytosis
ANS:g B
Opsonizationgpromotesgphagocytosisgbygbindinggtogcellsgorgantigens.

DIF: Levelg1 REF:g g p.g35

3. Selectgthegtermgthatgdescribesgcellsgorgtissuegfromgaggeneticallygdifferentgindividualgwithingth
egsamegspecies.
a. Allogeneic
b. Autologous
c. Xenogeneic
d. Autograft
ANS:g A
Allogeneicgcellsgorgtissuegcomegfromgaggeneticallygdifferentgindividualgwithingthegsamegspeci
es.

DIF: Levelg1 REF:g g p.g33

4. Selectgthegsubstancegthatgregulatesgthegactivitygofgothergcellsgbygbindinggtogspecificgreceptors.
a. Cytokines
b. Complement
c. Immunoglobulins
d. Anaphylatoxin
ANS:g A
Cytokinesgaregproteinsgsecretedgbygcellsgthatgregulategthegactivitygofgothergcellsgbygbindinggtog
specificgreceptors.




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,DOWNLOADgTHEgTestgBankgforgBasicgandgAppliedgConceptsgofgBloodgBankinggandgT
ransfusiongPracticesg4thgEditiongHoward
DIF: Levelg1 REF:g g p.g23

5. Whichgofgthegfollowinggisgresponsiblegforgthegactivationgofgthegclassicgpathwayg
ofgcomplement?
a. Bacteria
b. Foreigngproteins
c. Virus
d. Antibodygboundgtogantigen
ANS:g D
Angantigen-
antibodygcomplexgactivatesgthegclassicalgcomplementgcascade,gwhereasgbacterialgmembranesg
activategthegalternativegpathway.

DIF: Levelg1 REF:g g p.g33

6. Whatgbiologicalgmoleculesgaregconsideredgthegmostgimmunogenic?
a. Carbohydrates
b. Lipids
c. Proteins
d. Enzymes
ANS:g C
Proteingmoleculesgaregthegmostgimmunogenic,gfollowedgbygcarbohydratesgandglipids,gwhichgte
ndgtogbegimmunologicallyginert.

DIF: Levelg2 REF:g g p.g24

7. Whatgpartgofgthegimmunoglobulingmoleculegdistinguishesgthegisotype?
a. Lightgchain
b. Heavygchain
c. Kappagchain
d. Lambdagchain
ANS:g B
Thegfivegdistinctivegheavy-
chaingmoleculesgdistinguishgthegclassgorgisotype.gEachgheavygchaingimpartsgcharacteristicgfeat
ures,gwhichgpermitgthemgtoghaveguniquegbiologicalgfunctions.

DIF: Levelg2 REF:g g p.g24

8. Selectgthegimmunoglobulingclassgproducedgfirstgingthegprimarygimmunegresponse.
a. IgG
b. IgE
c. IgA
d. IgM
ANS:g D
IgMgantibodiesgaregproducedgfirst,gfollowedgbygthegproductiongofgIgGgantibodies.

DIF: Levelg1 REF:g g p.g28

9. Ingagserologicgtest,gthegtermgprozonegisgalsogknowngas:


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, DOWNLOADgTHEgTestgBankgforgBasicgandgAppliedgConceptsgofgBloodgBankinggandgT
ransfusiongPracticesg4thgEditiongHoward
a. equivalence.
b. antigengexcess.
c. antibodygexcess.
d. serum-to-cellgratio.
ANS:g C
Antibodygexcessgisgtermedgprozone,goftengleadinggtogagfalse-negativegreaction.

DIF: Levelg1 REF:g g p.g38

10. Whatgisgthegpotentialgeffectgingagtubegagglutinationgtestgifgagredgcellgsuspensiongwith
a concentrationggreatergthang5%gisgused?
g g
a. Falsegnegatives
b. Falsegpositives
c. Hemolysis
d. Nogeffect
ANS:g A
Antigengexcessgisgtermedgpostzonegandgwillglessengthegreaction,gcausinggagfalse-negative.

DIF: Levelg3 REF:g g p.g38

11. Aftergaddinggantigengandgantibodygtogagtestgtube,goneglargegagglutinategwasgobserved.gHo
wgshouldgthisgreactiongbeggraded?
a. 2+
b. 3+
c. 4+
d. 0
ANS:g C
Oneglargegagglutinategisggradedgag4+greaction.

DIF: Levelg2 REF:g g p.g39

12. Selectgthegportiongofgthegantibodygmoleculegthatgimpartsgthegantibody’sguniquegclassgfunction.
a. Constantgregiongofgthegheavygchain
b. Constantgregiongofgtheglightgchain
c. Variablegregiongofgthegheavygchain
d. Variablegregiongofgtheglightgchain
ANS:g A
Thegheavy-chaingconstantgregionghasgthegfunctiongofgthegclass.

DIF: Levelg1 REF:g g p.g26

13. Whatgportiongofgthegantibodygmoleculegbindsgtogreceptorsgongmacrophagesgandgassistsgingth
egremovalgofgantibodygboundgtogredgcells?
a. Fabgfragment
b. Hingegregion
c. Fcgfragment
d. Jgchain

ANS:g C



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