Test Bank for Basic and Clinical Pharmacology 4th Edition,(Katzung, 2017), Chapter 1-66 All Chapters

TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY FO
g g g g g g


R NURSES 19th EDITION BY MICHELLE WILLIHNGANZ CH
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APTER 1-48 g




Chapterg01:gDruggDefinitions,gStandards,gandgInformationgSourcesgWillihnganz:gClayton’sgBa
sicgPharmacologygforgNurses,g19thgEdition



MULTIPLEgCHOICE

1. WhichgnamegidentifiesgagdrugglistedgbygthegUSgFoodgand
DruggAdministrationg(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:g C
Thegofficialgnamegisgthe
namegundergwhichgagdruggisglisted
gbygthegFDA.gThegbrandgname,gorgtrademark,gisgthegnameggi

vengtogagdruggbygitsgmanufacturer.gThegnonproprietary,gorgg
eneric,gnameg isg providedg bygtheg Unitedg Statesg Adoptedg
NamesgCouncil.
DIF:gCognitivegLevel:gKnowledge REF:gp.g9
OBJ:g1NAT:gNCLEXgClientgNeedsgCategory:gSafe,gEffectivegCaregEnvironme
ntgTOP:gNursinggProcessgStep:gAssessment CON:
PatientgEducation

2. Whichgsourcegcontainsginformationgspecificgtognutritionalgsupplements?
a. USPgDictionarygofgUSANg&gInternationalgDruggNames
b. NaturalgMedicinesgComprehensivegDatabase
c. UnitedgStatesgPharmacopoeia/NationalgFormularyg(USPgNF)
d. DruggInteractiongFacts
ANS:gC
UnitedgStatesgPharmacopoeia/NationalgFormularygcontainsginformationgspecificgtog nutrition
algsupplements.gUSPgDictionarygofgUSANg&gInternationalgDruggNamesgisgagcompilationgofg
druggnames,gpronunciationgguide,gandgpossiblegfuturegFDAgapprovedgdrugs;gitgdoesgnotginclu
degnutritionalgsupplements.gNaturalgMedicinesgComprehensivegDatabasegcontainsgevidence-
basedginformationgongherbalgmedicinesgandgherbalgcombinationgproducts;gitgdoesgnotgincludeg
informationgspecificgtognutritionalgsupplements.gDruggInteractiongFactsgcontainsgcomprehen
siveginformationgongdrugginteractiongfacts;gitgdoesgnotgincludegnutritionalgsupplements.

DIF:gCognitivegLevel:gKnowledge REF:gp.g4
OBJ:g3gNAT:gNCLEXgClie
ntgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gAssessment CON:gNutritiong|gPatientgEducation

,TestgBankgForgClayton’sgBasicgPharmacologygforgNursesg19thgEditio 2
n 3. Whichgdruggreferencegcontainsgdruggmonographsgthatgdescribegallgdrugsgingagtherapeuticgclass?
a. DruggFactsgandgComparisons
b. DruggInteractiongFacts
c. HandbookgongInjectablegDrugs
d. Martindale—ThegCompletegDruggReference
ANS:gA
DruggFactsgandgComparisonsgcontainsgdruggmonographsgthatgdescribegallgdrugsging
agtherapeuticgclass.gMonographsgaregformattedgasgtablesgtogallowgcomparisongofgsimi
largproducts,gbrandgnames,gmanufacturers,gcostgindices,gandgavailablegdosagegforms
gOnlinegversiongisgavailable.



DIF:gCognitivegLevel:gKnowledge REF:gp.g4gTableg1.2
OBJ:g g 3 NAT:gNCLEXgClientgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gAssessment CON:gSafetyg|gPatientgEducationg|gClinicalgJudgment

4. Whichgdruggreferencegcontainsgmonographsgaboutgvirtuallygeverygsingle-
entitygdruggavailablegingthegUnitedgStatesgandgdescribesgtherapeuticgusesgofgdrugs,gincludin
ggapprovedgandgunapprovedguses?
a. Martindale:gThegCompletegDruggReference
b. AHFSgDruggInformation
c. DruggReference
d. DruggFactsgandgComparisons
ANS:gB
AHFSgDruggInformationgcontainsgmonographsgaboutgvirtuallygeverygsingle-
entitygdruggavailablegingthegUnitedgStatesgandgdescribesgtherapeuticgusesgofgdrugs,gincludingg
approvedgandgunapprovedguses.

DIF:gCognitivegLevel:gKnowledge REF:gp.g4gTableg1.2
OBJ:g g 3 NAT:gNCLEXgClientgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gPlanning CON:gSafetyg|gPatientgEducationg|gClinicalgJudgment

5. Whichg onlineg drugg referenceg makesg availableg tog healthcareg providersg andg theg publicg
agstandard,gcomprehensive,gup-to-
dateglookgupgandgdownloadablegresourcegaboutgmedicines?
a. AmericangDruggIndex
b. AmericangHospitalgFormulary
c. DailyMed
d. DruggReference
ANS:gC
DailyMedgmakesgavailablegtoghealthcaregprovidersgandgthegpublicgagstandard,gcomprehensiv
e,gup-to-
dateglookgupgandgdownloadablegresourcegaboutgmedicines.gThegAmericangDruggIndexgisgnotg
appropriategforgpatientguse.gThegAmericangHospitalgFormularygisgnotgappropriategforgpatient
guse.gThegdruggreferencegisgnotgappropriategforgpatientguse.



DIF:gCognitivegLevel:gKnowledge REF:gp.g3g|gp.g4
OBJ:g3gNAT:gNCLEXgClien
tgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gImplementation
CON:gSafetyg|gPatientgEducationg|gClinicalgJudgment

6. WhichglegislationgauthorizesgthegFDAgtogdeterminegthegsafetygofgagdruggbeforegitsgmarketing?
a. FederalgFood,gDrug,gandgCosmeticgActg(1938)

,TestgBankgForgClayton’sgBasicgPharmacologygforgNursesg19thgEditio 3
n b. DurhamgHumphreygAmendmentg(1952)
c. ControlledgSubstancesgActg(1970)
d. KefauvergHarrisgDruggAmendmentg(1962)
ANS:gA
ThegFederalgFood,gDrug,gandgCosmeticgActgofg1938gauthorizedgthegFDAgtogdeterminegthegsa
fetygofgallgdrugsgbeforegmarketing.gLatergamendmentsgandgactsghelpedgtightengFDAgcontrolg
andgensuregdruggsafety.gThegDurhamgHumphreygAmendmentgdefinesgthegkindsgofgdrugsgthat
gcannotgbegusedgsafelygwithoutgmedicalgsupervisiongandgrestrictsgtheirgsalegtogprescriptiongby

gaglicensedgpractitioner.gThegControlledgSubstancesgActgaddressesgonlygcontrolledgsubstance

sgandgtheirgcategorization.gThegKefauvergHarrisgDruggAmendmentgensuresgdruggefficacygand
ggreatergdruggsafety.gDruggmanufacturersgaregrequiredgtogprovegtogthegFDAgthegeffectivenessg

ofgtheirgproductsgbeforegmarketinggthem.

DIF:gCognitivegLevel:gKnowledge REF:g p.g5gTablegl.3
OBJ:g5
NAT:gNCLEXgClientgNeedsgCategory:gPhysiologicalgIntegrit
ygTOP:gNursinggProcessgStep:gAssessment
CON:gSafetyg|gPatientgEducationg|gEvidenceg|gHealthgCaregLaw

7. Whichgclassificationgdoesgmeperidineg(Demerol)gfallgunder?ga.
I
b. II
c. III
d. IV
ANS:gB
Meperidineg(Demerol)gisgagSchedulegIIgdrug;gitghasgaghighgpotentialgforgabusegandgmaygleadgt
ogseveregpsychologicalgandgphysicalgdependence.gSchedulegIgdrugsghaveghighgpotentialgforga
busegandgnogrecognizedgmedicalguse.gSchedulegIIIgdrugsghavegsomegpotentialgforgabuse.gUse
gmaygleadgtoglowgtogmoderategphysicalgdependencegorghighgpsychological gdependence.

SchedulegIVgdrugsghaveglowgpotentialgforgabuse.gUsegmaygleadgtoglimitedgphysicalgorgpsycho
logicalgdependence.

DIF:gCognitivegLevel:gKnowledge REF:gp.g10
OBJ:g2gNAT:gNCLEXgClien
tgNeedsgCategory:gSafe,gEffectivegCaregEnvironment
TOP:gNursinggProcessgStep:gAssessment CON:gPatientgEducationg|gAddictiong|gPain

8. WhichgactiongwouldgthegFDAgtakegtogexpeditegdruggdevelopmentgandgapprovalgforgangoutbrea
kgofgsmallpox?
a. Listgsmallpoxgasgaghealthgorphangdisease.
b. Omitgthegpreclinicalgresearchgphase.
c. Extendgthegclinicalgresearchgphase.
d. Fastgtrackgtheginvestigationalgdrug.
ANS:gD
OncegthegInvestigationalgNewgDruggApplicationghasgbeengapproved,gthegdruggcangreceiveghi
ghestgprioritygwithingthegagency,gwhichgisgcalledgfastgtracking.gAgsmallpoxgoutbreakgwouldgb
ecomegagprioritygconcerngingthegworld.gOrphangdiseasesgaregnotgresearchedgingagprioritygman
ner.gPreclinicalgresearchgisgnotgomitted.gExtendingganygphasegofgthegresearchgwouldgmeangagl
ongergtimegtogdevelopgagvaccine.gThegFDAgmustgensuregthatgallgphasesgofgthegpreclinicalgan
dgclinicalgresearchgphaseghavegbeengcompletedgingagsafegmanner.

DIF:gCognitivegLevel:gKnowledge REF:gp.g7 OBJ:g5

, TestgBankgForgClayton’sgBasicgPharmacologygforgNursesg19thgEditio 4
n NAT:gNCLEXgClientgNeedsgCategory:gSafe,gEffectivegCaregEnvironment
gTOP:gNursinggProcessgStep:gAssessment
CON:gHealthgCaregLawg|gHealthgCaregPolicyg|gInfectiong|gCaregCoordination

9. Whichgstatementgisgtruegaboutgover-the-counterg(OTC)gdrugs?
a. TheygaregnotglistedgingthegUSPgNF.
b. Agprescriptiongfromgaghealthcaregprovidergisgneeded.
c. Theygaregsoldgwithoutgagprescription.
d. Theygaregknowngonlygbygtheirgbrandgnames.
ANS:gC
OTCgmedicationsgdognotgrequiregagprescription.gAgvarietygofgnames,gbothggenericgandgtrade,g
cangbegusedgforgindividualgdrugsgsoldgOTC.gOTCgdrugsgareglistedgingthegUSPgNF.gPrescriptio
ngdrugsgrequiregangordergbygaghealthgprofessionalgwhogisglicensedgtogprescribe,gsuchgasgagphy
sician,gnursegpractitioner,gphysiciangassistant,gorgdentist.

DIF:gCognitivegLevel:gComprehension REF:gp.g2
OBJ:g2gNAT:gNCLEXgClie
ntgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gPlanning CON:gPatientgEducation

10. Whichgisgthegmostgauthoritativegreferencegforgmedicationsgthatgareginjected?
a. Martindale:gThegComplete
b. HandbookgongInjectablegDrugs
c. DailyMed
d. HandbookgofgNonprescriptiongDrugs
ANS:gB
ThegHandbookgongInjectablegDrugsgisgthegmostgcomprehensivegreferencegavailablegongthegt
opicgofgcompatibilitygofginjectablegdrugs.gItgisgagcollectiongofgmonographsgforgmoregthang30
0ginjectablegdrugsgthatgareglistedgalphabeticallygbyggenericgname.

DIF:gCognitivegLevel:gKnowledge REF:gp.g4
OBJ:g3gNAT:gNCLEXgClie
ntgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gAssessment CON:gClinicalgJudgmentg|gSafety

11. WhichgstatementgisgtruegaboutgLomotil?
a. Abusegpotentialgforgthisgdruggisglow.
b. Psychologicalgdependencygisglikely.
c. Theregisgaghighgpotentialgforgabuse.
d. Thisgdruggisgnotgagcontrolledgsubstance.
ANS:gA
Lomotil,gagSchedulegVgdrug,ghasgangabusegpotentialgofglimitedgphysicalgorgpsychologicalgdep
endencegliabilitygcomparedgwithgdrugsgingSchedulegIV.gBecausegabusegpotentialgisglowgwithg
agSchedulegVgdrug,gagprescriptiongmaygnotgbegrequired.gPsychologicalgdependencygisgnotglik
elygwithgagSchedulegVgdrug.gSchedulegVgdrugsgaregclassifiedgasgcontrolledgsubstances.

DIF:gCognitivegLevel:gKnowledge REF:gp.g5gBoxg1.1
OBJ:g2gNAT:gNCLEXgClie
ntgNeedsgCategory:gPhysiologicalgIntegrity
TOP:gNursinggProcessgStep:gAssessment CON:gClinicalgJudgmentg|gSafetyg|gPatientgEducation
12. Whichgmedicationgorderedgforgagpatientgwithgagsubstancegabuseghistoryghasgtheggreate
stgriskgforgabuse?
a. Lomotil