Test Bank for Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378 All Chapters 1-20

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Chapterg1ggAgCasegforgEvolutionarygThinking:gUnderstandinggHIV
1) IngwhichgofgthegfollowinggregionsghasgAIDSgkilledgtheglargestgnumbergofgindividuals?
A) India
B) Sub-SaharangAfrica
C) UnitedgStates
D) China
E) UnitedgKingdomgAnswer:gBgSection:g1.1
Skill:gKnowledge/Comprehension
2) ThegHIVgvirusgcontainsgallgofgthegfollowinggcomponentsgexceptg .
A) integrase
B) double-strandedgRNA
C) single-strandedgRNA
D) reversegtranscriptase
E) proteasegAnswer:gBgSection:g1.1
Skill:gKnowledge/Comprehension


3) ThegacronymgHIVgstandsgforgwhichgofgthegfollowing?
A) humangintercellulargvirus
B) humangimmunegvirus
C) humangimmunodeficiencygvirus
D) humangimmunitygvirus
E) humangimmunodeficiencygvectorgAnswer:gC
Section:g1.1
Skill:gKnowledge/Comprehension


4) WhichgofgthegfollowinggenzymesgisgresponsiblegforgtranscribinggviralgRNAgintogDNA?

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A) RNAgpolymerase
B) reversegtranscriptase
C) DNAgpolymerase
D) reversegintegrase
E) RNAgduplicasegAnswer:gBgSection:g1.1
Skill:gKnowledge/Comprehension
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5)
ThegproteinsgthatgenablegthegHIVgvirusgtogbindgtogcellsgaregtypicallygCD4gandgCCR5.gOn
whatgtypegofgcellsgaregthesegproteinsgtypicallygobserved?
g

A) plasmagcells
B) dendriticgcells
C) effectorghelpergTgcells
D) memoryghelpergTgcells
E) bothgCgandgDgAnswer:gEgSection:g1.1
Skill:gKnowledge/Comprehension


6)
ThegAIDSgphasegofgHIVginfectiongbeginsgwhengthegconcentrationgofgCD4gTgcellsgingtheg
bloodgdropsgbelowgwhatgconcentration?
A) 2,000gcellsgpergcubicgmillimeter
B) 1,000gcellsgpergcubicgmillimeter
C) 500gcellsgpergcubicgmillimeter
D) 200gcellsgpergcubicgmillimeter
E) NogCD4gTgcellsgaregobserved.gAnswer:gD
Section:g1.1
Skill:gKnowledge/Comprehension


7) WhichgofgthegfollowinggdruggcategoriesgaregusedgtogtreatgHIVginfections?
A) integraseginhibitors
B) proteaseginhibitors
C) reversegtranscriptaseginhibitors
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D) DNAseginhibitors
E) fusionginhibitorsgAnswer:gDgSection:g1.2
Skill:gKnowledge/Comprehension


8) CoreceptorginhibitorsgblockgHIVginfectiongbygpreventinggwhichgofgthegfollowing?
A) bindinggofgthegHIVgviriongontogthegplasmagmembrane
B) bindinggofgthegHIVgviriongontogthegCCR5greceptor
C) bindinggofgthegHIVgviriongontogtheggp120gprotein
D) degradinggthegcoreceptorgsogthegviriongcannotgattach
E) bindinggofgthegHIVgviriongontogthegCD4greceptorgAnswer:gB
Section:g1.2
Skill:gApplication/Analysis
9) Whatgisgthegeffectgofgtheg∆32gallelegofgCCR5gongHIVgbinding?
A)
appearsgongthegsurfacegofgCD4gTgcells,gbutgthegHIVgviriongisgunablegtoginfectgtheghostgcel
l
B) doesgnotgappeargongthegsurfacegofgCD4gTgcells
C) appearsgongthegsurfacegofgthegCD4gTgcellsgandginactivatesgthegviriongupongbinding
D) interferesgwithgbindinggofgthegviriongtogthegCD4greceptorgprotein
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E)
appearsgongthegsurfacegofgthegCD4gTgcellsgandgcausesgthegviriongtoglysegupongbindinggAn
swer:gB
Section:g1.3
Skill:gApplication/Analysis
10)
Theg∆32gallelegofgCCR5gisgfoundgatgtheghighestgfrequencygingwhichgofgthegfollowinggpop
ulations?
A) Africans
B) Japanese
C) NorthgAmericans
D) Europeans
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E) SouthgAmericansgAnswer:gDgSection:g1.3
Skill:gKnowledge/Comprehension


11) HIV-
1gisgbelievedgtoghavegbeengtransmittedgtoghumansgfromgwhichgofgthegfollowinggorganisms?
A) gorillas
B) sootygmangabeys
C) Africanggreengmonkeys
D) chimpanzees
E) baboonsgAnswer:gDgSection:g1.4
Skill:gKnowledge/Comprehension
12) HIV-
1gGroupgMgisgresponsiblegforg95%gofghumanginfections.gWhengisgitgestimatedgthatgHIV-
1gGroupgMgwasgtransferredgtoghumans?
A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer:gCgSection:g1.4
Skill:gKnowledge/Comprehension


13) AntibodiesgandgkillergTgcellsgrecognizegHIVgorgHIV-
infectedgcellsgbygbindinggtogshortgpiecesgofgviralgproteinsgdisplayedgongthegvirusgorgtheginfectedg
hostgcell.gThesegshortgpiecesgofgviralgproteinsgaregcalledg .
A) coatgproteins
B) virosomes
C) proteosomes
D) epitopes
E) episomesgAnswer:gD
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Section:g1.5
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