URATE SOLUTIONS b
A 1 year-
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old Thoroughbred stallion is presented with difficulty walking for the past week.
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Examination reveals ataxia in the pelvic limbs and there is a tendency for him to over
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reach in all four limbs when ambulating.
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Which one of the following choices is the most common cause of these signs in the ho
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rse? b
A - Tetanus
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B - Botulism
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C - Cervical vertebral malformation/malarticulation
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D - Lead toxicity
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E - Occipitoatlantoaxial malformation/malarticulation - Precise Answer ✔✔...
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A 1-
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year old female spayed Doberman Pinscher has presented after being hit by a car. Init
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ial chest radiographs show mild contusions, and the patient appears to be otherwise st
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able. A right mid-
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shaft long oblique femoral fracture has been identified. Routine pre-
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operative blood work is unremarkable. A buccal mucosal bleeding test (BMBT) is el
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evated at 6 minutes. What will you administer prior to surgery?
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Whole blood transfusion b b
Vitamin K b
,Desmopressin acetate b
1,25 dihydrocholecalciferol -
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bPrecise Answer ✔✔The correct answer is desmopressin acetate (DDAVP). Adminis
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tration of desmopressin results in release of von Willebrand factor, which will help th
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is patient with clotting. Given this dog's breed and elevated BMBT there is a very stro
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ng likelihood she is afflicted with von Willebrand's disease. In Dobermans this result
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s in an inability to form a clot. This can be life threatening if the dog is taken to surger
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y. b
A whole blood transfusion does not provide an adequate source of von Willebrand fa
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ctor but may be necessary if the patient's bleeding cannot be controlled despite appro
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priate pre- b
operative measures. 1,25 dihydrocholecalciferol is the active form of vitamin D whic
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h aids intestinal resorption of calcium. The BMBT does not assess factors 2, 7, 9, or 1
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0 and therefore vitamin K is not indicated.
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A 10- b
year old Golden Retriever has presented for a progressive onset of exercise intoleranc
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e and voice change. On physical exam the patient is noted to have a 7/9 body conditio
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n score. Mucous membranes are pink. Capillary refill time is less than 2 seconds. Lun
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g sounds are clear bilaterally. Stridorous breathing is noted on inspiration. Laryngeal
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paralysis is suspected and a sedated laryngeal exam has been recommended. The ow
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ner agrees to routine blood work, chest radiographs, and a laryngeal examination. W
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hich of the following medications will help assist in evaluation of laryngeal function?
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Propofol
Dopamine
Ketamine
Doxapram
Diphenhydramine - b
bPrecise Answer ✔✔Doxapram is a central nervous stimulant that has effects on respi
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ratory centers. It is thought that it may work by stimulating the reflex activation of car
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otid and aortic chemoreceptors. At one point, it was used in critical care patients duri
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,ng resuscitation efforts; however, this has fallen out of favor since doxapram results i
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n increased work associated with respiration without an increased amount of arterial
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oxygenation. When performing a laryngeal exam, the goal is to have the patient just d
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eep enough so you can perform a laryngeal exam. Injectable anesthetics such as thiop
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ental or propofol are used. Overzealous administration of these can result in a false di
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agnosis of laryngeal paralysis and it is therefore recommended to administer Doxapr
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am to help stimulate respiration and definitively confirm your diagnosis.
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Ketamine is an NMDA antagonist and can result in increased jaw tone as well as over
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all muscle tone. Although its cardiopulmonary effects are minimal, it does not stimul
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ate respiration.b b
Dopamine is a precursor to norepinephrine and acts on alpha and beta-
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1 receptors. It is typically used in critical care settings to help increase blood pressure
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. b
Diphenhydramine is the antihistamine also known as Benadryl. It competitively inhi b b b b b b b b b b
bits histamine at H1 receptors. Along with its antihistamine properties, it has sedative
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and anti-tussive effects.
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Propofol is a rapid acting injectable anesthetic which can result in hypotension, brady
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cardia, and apnea. b b
A 10- b
year old male castrated domestic short hair presents for lethargy. A blood smear sho
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ws Heinz bodies in the erythrocytes, and the blood is grossly brown in color. Which o
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f the following is responsible for causing these changes in the blood of this cat?
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Chocolate toxicity b
Lily ingestion b
Aspirin administration b
, Acetaminophen administration b
Rodenticide toxicity - Precise Answer ✔✔Explanation - b b b b b b
bThe correct answer is acetaminophen administration. The cat has signs of methemog
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lobinemia, which is caused by oxidative damage to the hemoglobin. Heinz bodies are
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busually present in animals with methemoglobinemia. Acetaminophen causes oxidati
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ve damage to cat blood due to the cat's inability to metabolize the drug efficiently.
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A 13- b
year old male castrated domestic long hair presents for polyphagia, weight loss, and v
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omiting. The owner notes that the cat appears restless, more active, and more aggress
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ive than before. Which test would diagnose the most likely cause for these signs?
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Liver panel b
Gastroduodenoscopy and biopsy b b
Abdominal ultrasound b
Renal panel and urinalysis b b b
Serum T4 - Precise Answer ✔✔Serum T4b b b b b b
Explanation - b
bThe correct answer is serum T4. This cat is most likely hyperthyroid. Polyphagia, we
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ight loss, and hyperactivity are classical clinical signs in a cat with hyperthyroidism.
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Other signs might include a dull haircoat, PU/PD, vomiting, diarrhea, and aggression
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. Lethargy, anorexia, and weakness are uncommon but can occur in a condition apath
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etic hypothyroidism.b
A 2 year old male castrated Boxer presents for exercise intolerance and syncopal epis
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odes. Cardiac auscultation reveals a 4/6 left systolic murmur heard best at the base of
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the heart. Thoracic radiographs show a mildly enlarged left ventricle and left atrium,
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and segmental enlargement of the ascending aorta. What is the most likely diagnosis?
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Boxer cardiomyopathy b