VERIFIED CORRECT ANSWERS
Codeine elixir - ---Answers----it is not self preserving,
sodium benzoate is an anti microbial preservative NOT citric
acid, propylene glycol is NOT a viscosity agent and saccharin
sodium is not an antioxidant
Non-sterile formulation for power for suspension - ---
Answers----for alcoholic aqueous liquids, the final volume
should be read by measuring at eye level from the bottom of
the meniscus, since the final volume is greater than 1.5mL a
syringe may be used to draw it up, but the precisions of the
final volume is NOT limited by interval size of the graduations
on the cylinder
extemporaneous communition and mixing powders - ---
Answers----finer end product can be achieved using a mortar
and pestle, only pharm or tech can perform this, this is non-
sterile compounding
surfactants - ---Answers----amphiphiles
cohesive force> adhesive force - ---Answers----tends to be
no mixing
Surfactants spontaneously concentrating at interface results
in what - ---Answers----decrease in interfacial tension
,Micelles are formed below CMS of surfactants - ---Answers--
--FALSE
Nonionic surfactants can be mixed with cationic or anionic
surfactants without affecting their properties - ---Answers---
-TRUE
Higher HLB - ---Answers----more hydrophilic, NOT
hydrophobic
Cationic surfactants - ---Answers----are strong antimicrobial
agents but poor surfactants
anionic surfactants - ---Answers----irritate the GI tract and
are not stable at pH<10
HLB value - ---Answers----determines how a surfactant may
be used in pharmaceutical formulations
W/O emulsion droplets - ---Answers----will sediment not
cream
O/W emulsions - ---Answers----can be made with hydrophilic
colloids and can be used to administer oil soluble drugs. They
are not made with hydrophobic emulsifying agents
, If a surfactant is used to make an O/W emulsions for oral
administration - ---Answers----a nonionic surfactant will
most likely be used because they are most widely used
Fine zinc powder can be used as an emulsifying agent because
it can reduce interfacial tension - ---Answers----FALSE it
cannot reduce interfacial tension at all
Cracking of emulsions - ---Answers----irreversible process
due to loss of function of emulsifying agents
Type of emulsify can be changed by addition of electrolytes or
water - ---Answers----TRUE
The velocity of sedimentation of droplets in an emulsion can be
reduced how? - ---Answers----by adding a viscosity agent
NOT a wetting agent
Cracking - ---Answers----aggregation and coalescence of
droplets to form separate phases
creaming - ---Answers----instability of emulsions
Suspensions are products resulting from what - ---Answers-
---incorporating insoluble drugs and additives into a liquid
medium