NR 507 EDAPT Week 6 Alterations in the
Endocrine System
,Alterations in the Endocrine System
ENDOCRENE
The pineal gland is responsible for regulating the sleep-wake cycle.
It must be bound to a protein and it bind to receptors on the cell membrane rather than inside
the cell membrane.
The anterior lobe of the pituitary produces its own hormones.
The endocrine cell can also secrete hormones that target cells directly close it. When this
occurs, this type of secretion is known as paracrine signaling.
This statement is true. Lipid-derived hormones cross the cell membrane and bind to receptors
in the cell’s cytoplasm.
Aldosterone promotes sodium reabsorption and potassium excretion in the kidneys.
They are located on the posterior lobes of the thyroid gland.
The posterior pituitary receives its hormones (oxytocin and ADH) from the hypothalamus. The
anterior pituitary produces its own hormones.
ADH is the only hormone listed that is produced by the hypothalamus.
The only steroid hormone listed is testosterone.
,Alterations in the Endocrine System
Overview of the Endocrine System
The purpose of the endocrine system is to maintain the body’s homeostasis using hormones.
Hormones are signaling molecules. Although a wide variety of hormones function within the
body, they share certain general characteristics:
1. Hormones have specific rates and rhythms of secretion. Three basic secretion patterns are:
(1) circadian or diurnal patterns, (2) pulsatile and cyclic patterns, and (3) patterns that
depend on levels of circulating substrates (e.g., calcium, sodium, potassium, or the
hormones themselves).
2. Hormones operate within feedback systems, either positive or negative, to maintain an
optimal internal environment.
3. Hormones affect only cells with specific receptors and then act on those cells to initiate
specific cell functions or activities.
When an endocrine cell receives a stimulus or command, this stimulates the endocrine cell to
secrete hormones into the blood stream. The hormones will then target and bind onto a
specific receptor on a target cell. This will cause the target cell to initiate a response as shown in
the diagram below:
, Alterations in the Endocrine System
Signaling Hormones