NU641 NU 641 MIDTERM EXAM (NEW UPDATE) ADVANCED CLINICAL PHARMACOLOGY QS & AS GRADE A 100% CORRECT (VERIFIED ANSWERS)

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NU641/ NU 641 MIDTERM EXAM: (NEW 2024/ 2
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025 UPDATE) ADVANCED CLINICAL PHARMACOLOGY
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| QS & AS| GRADE A| 100% CORRECT (VERIFIED AN
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SWERS)




first line drug for strep throat - ANS ✓penicillin v potassium PO x10 days
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if allergic to PCN, give amoxicillin
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before prescribing antiHTN meds to newly diagnosed pt -
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ANS ✓EKG & blood work
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thiazide diuretics - ANS ✓-cause ED
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-first line of tx for uncomplicated stage I HTN
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PCN allergy - ANS ✓use macrolides instead
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amoxicillin - ANS ✓avoid in mono patients
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complication of quinolones - ANS ✓-Achilles tendon rupture
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-do not use in children under 18 because of growing cartilage
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Benadryl - ANS ✓avoid in elderly
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use Claritin instead
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spironolactone - ANS ✓-potassium sparing diureticu u u u u




-caution w/ ACE: watch for hyperkalemia
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warfarin/coumadin - ANS ✓-do not take garlic, St. john's wart u u u u u u u u u




-increases bleeding time u u




sat john's wart - ANS ✓-used for depression, menopausal symptoms
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decreases effectiveness of digoxin & birth control (causes breakthrough bleeding
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)

-do not use with celexa
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antiplatelet meds - ANS ✓- u u u u




garlic can exaggerate effects & inhibit action of platelets in the body
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-ex: indomethacin, dipyridamole, Plavix, aspirin
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blood thinners - ANS ✓-aspirin & warfarin
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-avoid garlic: can increase risk of bleeding
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protease inhibitors - ANS ✓- u u u u




garlic may reduce blood levels of protease inhibitors
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-used to treat HIV u u u




-ex: indinavir, ritinavir, saquinavir
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SSRI - ANS ✓-zoloft
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-do not take st. john's wart, ginseng, ginko biloba
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risk of serotonin syndrome when using citalopram (celexa) with tramadol (ultra
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m) or elavil
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-if 10 weeks of therapy is ineffective, change drug within the SAME class.
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side effects of diuretics - ANS ✓-hyperuricemia
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-hyperglycemia

-hypokalemia

-ED



disulfuram reaction - ANS ✓-changes the way your body breaks down alcohol
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-alcohol with disulfiram causes nausea/vomiting, headache
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-avoid alcohol 1 day before, during therapy, and 72 hours after
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