PATHOPHYSIOLOGY EXAM 1 2023-2024 m m m
QUESTIONS AND ANSWERS. m m
An ordered photographic display of a set of chromosomes
m m m m m m m m
from a single cell is a(n):
m m m m m
A) metaphase spread. m
B) autosomal spread. m
C) karyotype.
D) anaphase spread. - ANSWER -c
m m m m
An error in which homologous chromosomes fail to separate
m m m m m m m m
during meiosis is termed:
m m m
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
,D) anaplasia. - ANSWER -b m m m
A somatic cell that does not contain a multiple of 23
m m m m m m m m m m
chromosomes is called: m m
A) an aneuploid cell.
m m
B) a euploid cell.
m m
C) a polyploidy cell.
m m
D) a haploid cell. - ANSWER -a
m m m m m
A 20-year-old pregnant female gives birth to a stillborn child.
m m m m m m m m m
Autopsy reveals that the fetus has 92 chromosomes. Which
m m m m m m m m
of the following describes this condition?
m m m m m
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSWER -c m m m
If a person is a chromosomal mosaic, the person may:
m m m m m m m m m
,A) be a carrier of the genetic disease.
m m m m m m
B) have a mild form of the genetic disease.
m m m m m m m
C) have two genetic diseases.
m m m
D) be sterile as a result of the genetic disease. - ANSWER -b
m m m m m m m m m m m
The most common cause of Down syndrome is:
m m m m m m m
A) paternal nondisjunction.
m
B) maternal translocations.
m
C) maternal nondisjunction.
m
D) paternal translocations. - ANSWER -c
m m m m
Risk factors for Down syndrome include:
m m m m m
A) fetal exposure to mutagens in the uterus.
m m m m m m
B) increased paternal age. m m
C) family history of Down syndrome.
m m m m
D) pregnancy in women over age 35. - ANSWER -d
m m m m m m m m
, A 13-year-old girl has a karyotype that reveals an absent
m m m m m m m m m
homologous X chromosome with only a single X
m m m m m m m
chromosome present. Her condition is called:
m m m m m
A) Down syndrome. m
B) Cri du chat syndrome.
m m m
C) Turner syndrome. m
D) Edward syndrome - ANSWER -c
m m m m
A child is diagnosed with cystic fibrosis. History reveals that
m m m m m m m m m
the child's parents are first cousins. Cystic fibrosis was most
m m m m m m m m m
likely the result of:
m m m
A) X inactivation.
m
B) genomic imprinting. m
C) consanguinity.
D) obligate carriers. - ANSWER -c
m m m m
Joey, age 9, is admitted to a pediatric unit with Duchenne
m m m m m m m m m m
muscular dystrophy. He inherited this condition through a:
m m m m m m m
QUESTIONS AND ANSWERS. m m
An ordered photographic display of a set of chromosomes
m m m m m m m m
from a single cell is a(n):
m m m m m
A) metaphase spread. m
B) autosomal spread. m
C) karyotype.
D) anaphase spread. - ANSWER -c
m m m m
An error in which homologous chromosomes fail to separate
m m m m m m m m
during meiosis is termed:
m m m
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
,D) anaplasia. - ANSWER -b m m m
A somatic cell that does not contain a multiple of 23
m m m m m m m m m m
chromosomes is called: m m
A) an aneuploid cell.
m m
B) a euploid cell.
m m
C) a polyploidy cell.
m m
D) a haploid cell. - ANSWER -a
m m m m m
A 20-year-old pregnant female gives birth to a stillborn child.
m m m m m m m m m
Autopsy reveals that the fetus has 92 chromosomes. Which
m m m m m m m m
of the following describes this condition?
m m m m m
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSWER -c m m m
If a person is a chromosomal mosaic, the person may:
m m m m m m m m m
,A) be a carrier of the genetic disease.
m m m m m m
B) have a mild form of the genetic disease.
m m m m m m m
C) have two genetic diseases.
m m m
D) be sterile as a result of the genetic disease. - ANSWER -b
m m m m m m m m m m m
The most common cause of Down syndrome is:
m m m m m m m
A) paternal nondisjunction.
m
B) maternal translocations.
m
C) maternal nondisjunction.
m
D) paternal translocations. - ANSWER -c
m m m m
Risk factors for Down syndrome include:
m m m m m
A) fetal exposure to mutagens in the uterus.
m m m m m m
B) increased paternal age. m m
C) family history of Down syndrome.
m m m m
D) pregnancy in women over age 35. - ANSWER -d
m m m m m m m m
, A 13-year-old girl has a karyotype that reveals an absent
m m m m m m m m m
homologous X chromosome with only a single X
m m m m m m m
chromosome present. Her condition is called:
m m m m m
A) Down syndrome. m
B) Cri du chat syndrome.
m m m
C) Turner syndrome. m
D) Edward syndrome - ANSWER -c
m m m m
A child is diagnosed with cystic fibrosis. History reveals that
m m m m m m m m m
the child's parents are first cousins. Cystic fibrosis was most
m m m m m m m m m
likely the result of:
m m m
A) X inactivation.
m
B) genomic imprinting. m
C) consanguinity.
D) obligate carriers. - ANSWER -c
m m m m
Joey, age 9, is admitted to a pediatric unit with Duchenne
m m m m m m m m m m
muscular dystrophy. He inherited this condition through a:
m m m m m m m
