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how do we know if a patient is healthy or unhealthy? - 🧠ANSWER
✔✔clinical exams, blood tests, rad investigations
normal values vary based on age, gender, genetics, environment, activity
level
the study of functional or structural changes due to disease - 🧠ANSWER
✔✔pathophysiology
describe pathphysiology - 🧠ANSWER ✔✔-uses knowledge of basic
anatomy and physiology
- studies cause and effect relationship of a disease
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,- explains clinical manifestations = signs and symptoms from a specific
disease
course of the disease from onset to end - 🧠ANSWER ✔✔pathogenesis
gross level vs microscopic level - 🧠ANSWER ✔✔gross level - organ
changes = heart hypertrophy with HTN
microscopic level - cellular level = liver fibrosis in cirrhosis
biopsy vs autopsy - 🧠ANSWER ✔✔biopsy = excision of small amounts of
living tissue
autopsy = exam of body and organs after death
identification of a disease is a ________
what is this based on? - 🧠ANSWER ✔✔diagnosis
based on history, eval of signs/symptoms, lab tests
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,symptoms vs signs - 🧠ANSWER ✔✔symptoms = patients complains,
cannot be measured (e.g. nausea, HA)
signs = can be measured or seen (e.g. temp, BP)
prognosis vs differential diagnosis - 🧠ANSWER ✔✔prognosis = outcome of
a particular disease
differential diagnosis = distinguishing diseases that may produce similar
signs and symptoms
causative factors in a disease - 🧠ANSWER ✔✔etiology
example of etiology - 🧠ANSWER ✔✔the flu virus is the etiological agent for
the flu
etiological factors can be: - 🧠ANSWER ✔✔1. congenital defects = defects
at birth
2. genetic disorders e.g. sickle cell
2. microorganisms = bacteria, virus, fungi, etc
3. immunologic dysfunctions e.g. autoimmune = SLE
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, 4. degenerative changes e.g. osteoarthritis
5. malignancy = cancers
6. metabolic, nutritional problems e.g. vitamin deficiency
7. trauma, burns, environ factors (heat, cold, pressure)
idiopathic vs iatrogenic - 🧠ANSWER ✔✔idiopathic - cause of disease is
unknown
iatrogenic - error/treatment/procedure may cause disease
what are predisposing factors/risk factors? - 🧠ANSWER ✔✔age, gender,
inherited factors, lifestyle environment, etc
e.g. smoking is a risk factor for heart disease and lung cancer
sudden/acute vs insidious onset of disease - 🧠ANSWER ✔✔sudden/acute
= e.g. MI, CVA (stroke)
insidious = gradual, vague, or mild signs e.g. flu
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