NBME PATHOLOGY FINAL EXAM 3 TESTBANK ACTUAL EXAM COMPLETE 300 QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) NEWEST UPDATED VERSION ALREADY GRADED A+

NBME PATHOLOGY FINAL EXAM TEST
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BANK | NEWEST ACTUAL EXAM COMPR
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EHENSIVE QUESTIONS AND VERIFIED AN
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SWERS GRADED A+ | 100% PASS | 2025 U
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Exceptionsgtogthegrulegofghowgcarcinomasgspread:g-
g ✔✔✔gCorrectgAnswerg >g Renalgcellgcarcinomag(spreadsgviaginvasiongof


grenalgvein)ghepatocellulargcarcinomag(invadesghepaticgvein),gfolliculargca


rcinomagofgthegthyroid,gchoriocarcinoma,gwhichgbothgspreadghematogen
ouslygalso.


Agbenigngtumorgofgthegepitheliumgisga:g-g ✔✔✔gCorrectg Answerg >
adenoma,gpapilloma


Necrosis:g-
g ✔✔✔gCorrectg Answerg >g Exogenousginjurygcausesgenzymaticgdegrada


tiongandgproteingdenaturationgofgagcell.gICgcomponentsgextravasate.g**T
here'sganginflammatorygprocessgunlikegapoptosis**


Coagulativegnecrosisgoccursgingthe:g-
g ✔✔✔gCorrectgAnswerg>g Causedgbygischemiagorginfarctiongtypically.gh


eart,gliver,gkidney.gOccursgingtissuesgsuppliedgbygendgarteries.gHighgcytop
lasmicgbindinggofgacidophilicgdye.
Proteinsgdenaturegfirstgfollowedgbygenzymaticgdegradation.

,Liquefactivegnecrosisgoccursgingthe:g-
g ✔✔✔gCorrectg Answerg >g brain,gbacterialgabscessgandgpleuralgeffusio


n.gOccursgingCNSgbecausegofghighgfatgcontentgthere.gUnlikegcoaggnecrosis
,genzymaticgdegradationgduegtogreleasegofglysosomalgenzymesgoccursgfir
st.


Agmalignantgtumorgofgepitheliumgis:g-g ✔✔✔gCorrectg Answerg >
adenocarcinoma,gpapillarygcarcinoma


Agbenigngtumorgofgthegbloodgvessels:g-g ✔✔✔gCorrectg Answerg >
hemangioma


Basicgcharacteristicsgofgagbenigngtumor:g-
g ✔✔✔gCorrectg Answerg >gwell-


differentiated,gnognecrosis,gwellgdemarcated,gnogmetastases,glowgmito
ticgactivity


Basicgcharacteristicsgofgagmalignantgtumor:g-
g ✔✔✔gCorrectg Answerg >gmaygbegpoorlygdifferentiated,gerraticggrowth,


glocallyginvasiveg/gdiffuse,gmaygmetastasize,glowgapoptosis




What'sgthegmechanismgbehindglowgapoptosisgingmalignancies?g-
g ✔✔✔gCorrectg Answerg>g upregulationgofgtelomerasegpreventsgshort


eninggofgthegtelomeresgandgthusgcellgdeath.

,Cachexia:g-
g✔✔✔gCorrectgAnswerg>g weightgloss,gmusclegatrophygandgfatiguegtha


tgoccurgingthegsettinggofgchronicgdiseaseg(AIDS,gcancer,gheartgfailure,gTB)
.gMediatedgbygTNF-alphag(calledgcachectin)gIFN-gammagandgIL-6.


DISEASEg--
gCANCERgAssociations:gAcanthosisgnigricansg(hyperpigmentationgandgep


ithelialgthickening)g-
g ✔✔✔gCorrectgAnswerg >g visceralgmalignanyg(espgstomach)




Agmalignantgtumorgofgbloodgvessels:g-g ✔✔✔gCorrectg Answerg >
angiosarcoma


CEA:g-
g ✔✔✔gCorrectg Answerg >g CarcinoEmbryonicgAntigen.gVerygnonspecifi


cgbutgproducedgbyg70%gofgcolorectalgandgpancreaticgcancers;galsogproduc
edgbyggastric,gbreastgandgmedullarygthyroidgcarcinomas


PSA:g-g ✔✔✔gCorrectg Answerg >g prostate-
specificgantigen.gUsedgtogfollowgprostategadenocarcinoma.gCangalsogbegel
evatedgingBPHg(benigngprostaticghyperplasia)gandgprostatitis.gQuestionab
legriskg/gbenefitgforgscreening.


S-100:g-
g ✔✔✔gCorrectg Answerg >g neuralgcrestgorigin,giegmelanomas,gneuralgtu


mors,gschwannomas,glangerhan'sgcellghistiocytosis.

, TRAP:g-g ✔✔✔gCorrectg Answerg >g Tatrate-
resistantgacidgphosphatase.gHairygcellgleukemia--agBgcellgneoplasm.


Agmalignantgtumorgofgblood:g-
g ✔✔✔gCorrectg Answerg >g leukemia,glymphoma




Agbenigngtumorgofgsmoothgmuscle:g-g ✔✔✔gCorrectg Answerg >
Leiomyoma


Agmalignantgtumorgofgsmoothgmuscle:g-g ✔✔✔gCorrectg Answerg >
leiomyosarcoma


Agbenigngtumorgofgstriatedgmuscle:g-g ✔✔✔gCorrectg Answerg >
rhabdomyoma


Agmalignantgtumorgofgstriatedgmuscle:g-g ✔✔✔gCorrectg Answerg >
rhabdomyosarcoma


Agbenigngtumorgofgconnectivegtissue:g-g ✔✔✔gCorrectg Answerg >
fibroma


Agmalignantgtumorgofgconnectivegtissue:g-g ✔✔✔gCorrectg Answerg >
fibrosarcoma