aWhat layer do neural crest cells develop from? - -Ectoderm
-At what embryonic age does the dental lamina begin to develop? - -6 weeks
-What are the three components of the tooth bud? - -Enamel Organ
Dental papilla
Dental sac
-What are the three morphologic stages of a developing tooth bud? - -Bud stage
Cap stage
Bell stage
-During the bell stage invagination of the epithelium occurs, which layer is essential
for enamel production? - -Stratum intermedium
-Which cells does the stellate reticulum support and protect? - -Ameloblasts
-What do remnants of Hertwig's epithelial root sheath persist as? - -Rests of
Malassez
-What is the origin of the dental papilla? - -Neural crest cells
-What does the dental papilla differentiate in to? - -Dentin and primordium of pulp
-What are enamel pearls? - -Cells of epithelial root sheath that remain attached to
dentin. Differentiate into ameloblasts and produce enamel
-What are the 7 steps (in order) of histophyisological differentiation of a tooth bud?
- -Initiation
Proliferation
Histodifferentiation
Morphodifferentiation
Apposition
Mineralization
Maturation
-During which stage of tooth development may problems that lead to anomalies of
tooth number occur? - -Initiation
-Which three stages of tooth development encompasses the bud, cap, early bell
and late bell? - -Proliferation
Histodifferentiation
Morphodifferentiation
-Disruptions of proliferation may result in what type of tooth anomalies? (4) - -Size
Proportion
Numbers
Twinning
, -Which stage of tooth development may lead to anomalies of the enamel, dentin,
and cementum? - -Morphodifferentiation
-What is the incidence of hyperdontia? Males vs females? - -0.3 - 3%
Males 2:1 females
-Is hyperdontia more common in maxilla or mandible? More common in primary
teeth or permanent teeth? - -Maxilla 90%
Permanent dentition 5x more common that primary
-Which permanent teeth are most frequently missing? List in order from most to
least common - -Third molars
Mandibular second pre molars
Maxillary lateral incisors
Maxillary second pre molars
-Name 9 syndromes that may be associated with supernumerary teeth - -Apert
Cleidocranial dysplasia
Gardner syndrome
Crouzon syndrome
Sturge Weber syndrome
Orofacialdigital Syndrome I
Hallermann-Strieff Syndrome - A
Cleft lip and palate
Down syndrome
-Which syndrome is associated with shovel shaped incisors?
A. Sturge Weber Syndrome
B. Cleidocranial dysplasia
C. Apert syndrome
D. Hallermann Strieff Syndrome-A - -C. Apert Syndrome
Narrow high palate
Cleft of soft palate
Delayed or ectopic eruption
Shovel shaped incisors
Hypoplastic midface
-Which syndrome is associated with osteomas of the jaw?
A. Orofiaciodigital Syndrome I
B. Apert Syndrome
C. Crouzon Syndrome
D. Gardner Syndrome - -D. Gardner Syndrome
Delayed eruption
Supernum teeth
Osteomas of the jaw
, -Agensis of third molars is associated with agenesis of which permanent tooth? - -
Maxillary lateral - either one or both
-What is the inheritance pattern for non syndromic hypodontia? - -Autosomal
dominant
-Which teeth (from most to least) commonly present as microdontia? - -Lateral
incisors
Second pre molars
Third molars
-Which tooth anomaly is characterized by: abortive attempt by single tooth to
divide; bifid crown with single root and pulp chamber? - -Gemination
-Which tooth anomaly is characterized by: complete cleavage of single bud results
in supernum mirror image tooth? - -Twinning
-Which race is fusion of teeth most commonly seen? - -Japenese (5%)
-Which tooth anomaly is characterized by: dental union of 2 embryologically
developing teeth two separate pulp chambers; separate or fused canals appear as
large bifid crown with one chamber; dentin is always confluent? - -Fusion
-Which tooth anomaly is characterized by fusion after root formation is completed?
What is a common cause? - -Concresence
Etiology: trauma
-What class drug is chloral hydrate? - -Non-barbituate
Sedative hypnotic
-What is the dosing range for Chloral Hydrate? What is the max dose? - -25 - 50
mg/kg (typically with CCHMC triple, dose at 15 - 25 mg/kg)
Max 100 mg
-What is the other name for Meperidine? What dug class is Meperidine? - -Demerol
Opiod, narcotic
-What are the most common side effects of meperidine? - -Hypotension
Respiratory depression
Emesis
Dizziness
Neurotoxic metabolite
-What is the dosage (mg/kg) for meperidine? What is the max dose? - -0.5 - 2
mg/kg
Max: 50 mg
-At what embryonic age does the dental lamina begin to develop? - -6 weeks
-What are the three components of the tooth bud? - -Enamel Organ
Dental papilla
Dental sac
-What are the three morphologic stages of a developing tooth bud? - -Bud stage
Cap stage
Bell stage
-During the bell stage invagination of the epithelium occurs, which layer is essential
for enamel production? - -Stratum intermedium
-Which cells does the stellate reticulum support and protect? - -Ameloblasts
-What do remnants of Hertwig's epithelial root sheath persist as? - -Rests of
Malassez
-What is the origin of the dental papilla? - -Neural crest cells
-What does the dental papilla differentiate in to? - -Dentin and primordium of pulp
-What are enamel pearls? - -Cells of epithelial root sheath that remain attached to
dentin. Differentiate into ameloblasts and produce enamel
-What are the 7 steps (in order) of histophyisological differentiation of a tooth bud?
- -Initiation
Proliferation
Histodifferentiation
Morphodifferentiation
Apposition
Mineralization
Maturation
-During which stage of tooth development may problems that lead to anomalies of
tooth number occur? - -Initiation
-Which three stages of tooth development encompasses the bud, cap, early bell
and late bell? - -Proliferation
Histodifferentiation
Morphodifferentiation
-Disruptions of proliferation may result in what type of tooth anomalies? (4) - -Size
Proportion
Numbers
Twinning
, -Which stage of tooth development may lead to anomalies of the enamel, dentin,
and cementum? - -Morphodifferentiation
-What is the incidence of hyperdontia? Males vs females? - -0.3 - 3%
Males 2:1 females
-Is hyperdontia more common in maxilla or mandible? More common in primary
teeth or permanent teeth? - -Maxilla 90%
Permanent dentition 5x more common that primary
-Which permanent teeth are most frequently missing? List in order from most to
least common - -Third molars
Mandibular second pre molars
Maxillary lateral incisors
Maxillary second pre molars
-Name 9 syndromes that may be associated with supernumerary teeth - -Apert
Cleidocranial dysplasia
Gardner syndrome
Crouzon syndrome
Sturge Weber syndrome
Orofacialdigital Syndrome I
Hallermann-Strieff Syndrome - A
Cleft lip and palate
Down syndrome
-Which syndrome is associated with shovel shaped incisors?
A. Sturge Weber Syndrome
B. Cleidocranial dysplasia
C. Apert syndrome
D. Hallermann Strieff Syndrome-A - -C. Apert Syndrome
Narrow high palate
Cleft of soft palate
Delayed or ectopic eruption
Shovel shaped incisors
Hypoplastic midface
-Which syndrome is associated with osteomas of the jaw?
A. Orofiaciodigital Syndrome I
B. Apert Syndrome
C. Crouzon Syndrome
D. Gardner Syndrome - -D. Gardner Syndrome
Delayed eruption
Supernum teeth
Osteomas of the jaw
, -Agensis of third molars is associated with agenesis of which permanent tooth? - -
Maxillary lateral - either one or both
-What is the inheritance pattern for non syndromic hypodontia? - -Autosomal
dominant
-Which teeth (from most to least) commonly present as microdontia? - -Lateral
incisors
Second pre molars
Third molars
-Which tooth anomaly is characterized by: abortive attempt by single tooth to
divide; bifid crown with single root and pulp chamber? - -Gemination
-Which tooth anomaly is characterized by: complete cleavage of single bud results
in supernum mirror image tooth? - -Twinning
-Which race is fusion of teeth most commonly seen? - -Japenese (5%)
-Which tooth anomaly is characterized by: dental union of 2 embryologically
developing teeth two separate pulp chambers; separate or fused canals appear as
large bifid crown with one chamber; dentin is always confluent? - -Fusion
-Which tooth anomaly is characterized by fusion after root formation is completed?
What is a common cause? - -Concresence
Etiology: trauma
-What class drug is chloral hydrate? - -Non-barbituate
Sedative hypnotic
-What is the dosing range for Chloral Hydrate? What is the max dose? - -25 - 50
mg/kg (typically with CCHMC triple, dose at 15 - 25 mg/kg)
Max 100 mg
-What is the other name for Meperidine? What dug class is Meperidine? - -Demerol
Opiod, narcotic
-What are the most common side effects of meperidine? - -Hypotension
Respiratory depression
Emesis
Dizziness
Neurotoxic metabolite
-What is the dosage (mg/kg) for meperidine? What is the max dose? - -0.5 - 2
mg/kg
Max: 50 mg
